Announcements & Documents
Moleküler Biyoloji ve Genetiğin Uygulamaları Ders Notu
Lecture Note
10/31/2017
Education Information
2003 - 2009
2003 - 2009Doctorate
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik, Turkey
1999 - 2003
1999 - 2003Postgraduate
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik, Turkey
1995 - 1999
1995 - 1999Undergraduate
Hacettepe University, Fen Fakültesi, Biyoloji Bölümü, Turkey
Dissertations
2009
2009Doctorate
Mayada Ağır metal stresine bağlı olarak anlatım yapan genlerin karakterizasyonu
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik
2003
2003Postgraduate
Schizosaccharomyces pombe Lindner Str. liquefaciens(Osterwalder)'de farklı ortam koşullarının bakır metabolizması üzerine etkileri
Istanbul University, Fen Bilimleri Enst., Molekküler Biyoloji Ve Genetik
Foreign Languages
C1 Advanced
C1 AdvancedEnglish
Research Areas
Life Sciences
Molecular Biology and Genetics
Genetic Engineering
Animal Molecular Genetics
Natural Sciences
Academic Titles / Tasks
2017 - Continues
2017 - ContinuesAssistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
2002 - Continues
2002 - ContinuesResearch Assistant PhD
Istanbul University, Faculty of Science, Depertment of Biology
Courses
Advising Theses
Continues
ContinuesPostgraduate
Ko-kültür Sistemiyle Antimikrobiyal Peptid Eldesi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
A.Yanık(Student)
Continues
ContinuesPostgraduate
Schizosaccharomyces pombe'de Metformin'in Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
C.Şeylan(Student)
2020
2020Postgraduate
Schizosaccharomyces pombe'de B-Hidroksibütirat Keton Cisimciğinin Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
H.ULUDAĞ(Student)
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota
Tarhan Ç.
EXPERIMENTAL PHYSIOLOGY
, vol.28, pp.1-14, 2024 (SCI-Expanded)
2023
2023Metformin extends the chronological lifespan of fission yeast by altering energy metabolism and stress resistance capacity.
Şeylan C., Tarhan Ç.
FEMS yeast research
, vol.23, 2023 (SCI-Expanded)
2021
2021Transcriptome sequencing and screening of genes related to glucose availability in Schizosaccharomyces pombe by RNA-seq analysis
Tarhan Ç., Çakır Ö.
GENETICS AND MOLECULAR BIOLOGY
, vol.44, no.3, 2021 (SCI-Expanded)
2019
2019A Genome-Wide Screen for Wortmannin-Resistant Mutants in Schizosaccharomyces pombe: The Phosphorylation-Impaired Mutants Are Resistant to Signaling Defect
Yilmazer M., Kartal B., Tarhan C., Ozarabaci I., Akcaalan S., Ozkan E., et al.
DNA AND CELL BIOLOGY
, vol.38, pp.1427-1436, 2019 (SCI-Expanded)
2019
2019Nutritional and health benefits of legumes and their distinctive genomic properties
Çakır Ö., Uçarlı C., Tarhan Ç., Pekmez M., Turgut Kara N.
Ciencia E Tecnologia De Alimentos
, vol.39, no.1, pp.1-12, 2019 (SCI-Expanded)
2016
2016EVRİMSEL DİNAMİKLERİN MEYDAN OKUYAN ÖZNESİ OLARAK HIV
TARHAN Ç.
Toplum ve Hekim
, vol.31, no.5, pp.371-375, 2016 (SCI-Expanded)
2012
2012Does copper stress lead to spindle misposition-dependent cell cycle arrest?
Tarhan C., Sarikaya A. T.
GENETICS AND MOLECULAR RESEARCH
, vol.11, no.4, pp.3824-3834, 2012 (SCI-Expanded)
2010
2010Expression of Human A4V Mutant Cu,Zn Superoxide Dismutase in Schizosaccharomyces pombe: Investigations of its Toxic Properties
Karaer S., Tarhan C., Pekmez M., HAMAD I., Arda N., Sarikaya A. T.
BIOCHEMICAL GENETICS
, vol.48, no.1-2, pp.113-124, 2010 (SCI-Expanded)
2007
2007The effect of superoxide dismutase deficiency on zinc toxicity in Schizosaccharomyces pombe
Tarhan C., Pekmez M., Karaer S., Arda N., Sarikaya A. T.
JOURNAL OF BASIC MICROBIOLOGY
, vol.47, no.6, pp.506-512, 2007 (SCI-Expanded)
2007
2007Fission yeast as a model for ALS disease
Karaer Uzuner S., Tarhan Ç., Hamad İ., Pekmez M., Arda E. Ş. N., Topal Sarıkaya A.
Journal Of Biotechnology , vol.2, no.131, pp.250, 2007 (SCI-Expanded)
Articles Published in Other Journals
2023
2023Functional Annotation of Uncharacterised Proteins Whose Expression Patterns Affect the Lifespan under Metformin Treatment in Fission Yeast
Tarhan Ç., Çalıcı Z., Özden B.
European Journal of Biology
, vol.82, no.2, pp.196-211, 2023 (Scopus)
2023
2023Evaluation of Proteins Released to Medium in Yeast-Bacteria Co-culture System
Yanık A., Tarhan Ç.
Journal of advanced research in natural and applied sciences (Online) , vol.9, no.2, pp.488-498, 2023 (Peer-Reviewed Journal)
2021
2021Effects of Scilla autumnalis Extracts on U87-MG Human Glioblastoma Cells
Pekmez M., Tarhan Ç., Zeytunluoğlu A., Turan M., Mete Ş. B., Köseler A.
Kafkas Tıp Bilimleri Dergisi , vol.11, no.2, pp.299-306, 2021 (Peer-Reviewed Journal)
2017
2017Palmiye yağı ve kanser gerçeği
Ertan H., Arı Ş., Günaydın K., Karagöz A., Turgut Kara N., Ay M., et al.
Herkese Bilim Teknoloji , vol.47, pp.6-7, 2017 (Non Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2023
2023Pioglitazone Increase Healthspan Possibly by Reducing Oxidative Stress in Fission Yeast
Çalıcı S. Z., Tarhan Ç., Özden B.
IX. International Congress of Molecular Medicine, İstanbul, Turkey, 18 - 20 December 2023, pp.16-17
2023
2023ANALYSIS OF UPREGULATED-UNCHARACTERIZED GENES INFLUENCING LIFESPAN UNDER METFORMIN TREATMENT IN FISSION YEAST
Tarhan Ç., Çalıcı Z., Özden B.
3rd INTERNATIONAL CONGRESS ON CONTEMPORARY SCIENTIFIC RESEARCH held on August 7-8, 2023 / Adana, Türkiye, Adana, Turkey, 7 - 08 August 2023, pp.54-55
2023
2023ANALYSIS OF UPREGULATED-UNCHARACTERIZED GENES INFLUENCING LIFESPAN UNDER METFORMIN TREATMENT IN FISSION YEAST
Tarhan Ç., Çalıcı S. Z., Özden B.
3. INTERNATIONAL CONGRESS ON CONTEMPORARY SCIENTIFIC RESEARCH, Adana, Turkey, 7 - 08 August 2023, pp.282
2022
2022Effects of The Active Ingredient of Green Tea Epigallocatechin gallate (EGCG) Polyphenol on Cell Metabolism and Aging
Tarhan Ç., Çetin B. N.
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Ankara, Turkey, 23 - 25 November 2022, pp.113
2019
2019Puccinellia distans - A potential plant to reveal boron toxicity and salt tolerance mechanisms
Hakki E. E., Pandey A., Khan M. K., Hamurcu M., Celik O., Gezgin S., et al.
European Biotechnology Congress, Valencia, Spain, 11 - 13 April 2019, vol.305
2019
2019A genome-wide screen for wortmann in and hydrogen peroxide resistant mutants in Schizosaccharomyces pombe
Yılmazer M., Kartal B., Tarhan Ç., Özarabacı İ., Akçaalan S., Özkan E., et al.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, vol.1, no.1, pp.163
2019
2019METFORMIN INCREASES LIFESPAN BY COMPLICATED MECHANISMS IN SCHIZOSACCHAROMYCES POMBE
ŞEYLAN C., KOÇ İ., TARHAN Ç.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, pp.18
2019
2019Effect of beta-hydroxybutyrate in aging process Schizosaccharomyces pombe
Uludağ H., TARHAN Ç., ÇAKIR Ö., Ataözü M.
7th international congress of The molecular Biology association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, pp.81
2015
2015Evrimde Moleküler Süreçler
TARHAN Ç.
V. Evrim Bilim ve Eğitim Sempozyumu 2015, İstanbul, Turkey, 19 - 20 December 2015, pp.1-2
2013
2013Absence of the Indy protein homolog prolongs the life span in the presence of high glucose levels in Schizosaccharomyces pombe
TARHAN Ç., TOPAL SARIKAYA A., Malcı A.
Pombe 2013, 7th International Fission Yeast Meeting 24 – 29 June 2013 | London, UK, United Kingdom, 1 - 04 June 2013, pp.151
2013
2013The effects of Astragalus chrysochlorus crude extract on cancer model of Schizosaccharomyces pombe cells
Karaer Uzuner S., Tarhan Ç., Arı Ş.
Pombe 2013, 7th International Fission Yeast Meeting, London, United Kingdom, 1 - 04 June 2013, pp.188
2013
2013Hydrocortisone effect on Schizosaccharomyces pombe's rad17+ gene expression.
TARHAN Ç., ŞATIR T. M., YILMAZER M., KARAER UZUNER S.
EMBO Conference Pombe 2013 7th International Fission Yeast Meeting, Londra, United Kingdom, 1 - 04 May 2013, no.185, pp.323
2011
2011The effect of copper stress on expression of the ace2 gene in Schizosaccharomyces pombe, another piece of puzzle
Tarhan Ç., Jafari Ghods F., PALABIYIK B., Çetinkaya B., Topal Sarıkaya A.
The 6th International Fission Yeast Meeting, United States Of America, 1 - 04 June 2011, vol.1, pp.225
2010
2010Does Copper Stress Affect the Organization of Microtubule in the Fission Yeast
TARHAN Ç., Topal SARIKAYA A.
Power of Microbes in Industry and Environment, Central European Symposium on Industrial Microbiology and Microbial Ecology, Croatia, 1 - 04 October 2010, pp.1-2
2009
2009Gene Expression Profiling of Copper Induced Responces in the Fission Yeast
TARHAN Ç., Topal SARIKAYA A.
The Fifth International Fission Yeast Meeting, Pombe 2009, Japan, 1 - 04 October 2009, pp.320
2008
2008Schizosaccharomyces pombe’de Bakır Stresine Bağlı Olarak Anlatım Yapan Genlerin Farklılık Gösterim Yöntemiyle Araştırılması
TARHAN Ç., Topal SARIKAYA A.
Ulusal Maya Moleküler Biyolojisi ve Biyoteknolojisi Sempozyumu, Bursa, Turkey, 1 - 04 May 2008, pp.12
2007
2007Fission yeast as a model for ALS disease
Karaer S., Tarhan C., Hamad I., Pekmez M., Arda N., Sarikaya A. T.
13th European Congress on Biotechnology (ECB 13), Barcelona, Spain, 16 - 19 September 2007, vol.131
2005
2005Studying on Zinc Toxicty and Antioxidant Defense Mechanism in Schizosaccharomyces pombe
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
The XXIInd International Conference on Yeast Genetics and Molecular Biiology, Slovakia, 1 - 04 September 2005, pp.36
2005
2005The cloning and expression of human ALS mutant Cu,Zn SOD into Schizosaccharomyces pombe
Karaer Uzuner S., TARHAN Ç., Topal SARIKAYA A.
The XXIInd International Conference on Yeast Genetics and Molecular Biiology, Slovakia, 1 - 04 September 2005, pp.236
2005
2005Çinko Toksisitesi ve Antioksidan Savunma Mekaniizmaları Üzerine Çlaışmalar
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
XIV. Ulusal Biyoteknoloji Kongresi, Eskişehir, Turkey, 1 - 04 September 2005, pp.322
2003
2003Mayada farklı ortam koşullarının süperoksit dismutaz aktivitesi üzerine etkileri.
TARHAN Ç., Topal SARIKAYA A.
XIII. Biyoteknoloji Kongresi, Çanakkale, Turkey, 1 - 04 August 2003, pp.294
2003
2003The Schizosaccharomyces pombe LYS7 gene is involved in copper metabolism.
Sarikaya A., TARHAN Ç.
21st International Conference on Yeast Genetics and Molecular Biology, Gothenburg, Sweden, 7 - 12 July 2003, vol.20
2002
2002Mayada hücre üremesi ve süperoksit dismutaz aktivitesi üzerine bakırın etkileri.
TARHAN Ç., Topal SARIKAYA A.
XVI. Ulusal Biyoloji Kongresi, Malatya, Turkey, 1 - 04 September 2002, pp.48
2001
2001Mayada ağır metal duyarlılığı üzerine pH’nın etkileri
AKMAN G., KIĞ C., TARHAN Ç., YAVUZ İ., Topal SARIKAYA A.
XII. Biyoteknoloji Kongresi, Balıkesir, Turkey, 1 - 04 September 2001, pp.132
Books & Book Chapters
2023
2023Yaşlanmanın Moleküler Temelleri
Tarhan Ç.
in: Geleceğin Yeni Sahipleri Yaşlılar, Ahmet AKGÜL Nur Elçin BOYACIOĞLU Sera YİĞİTER, Editor, İÜC Yayınevi, İstanbul, pp.13-20, 2023
2020
2020Virüslerin İnsan Evrimindeki Rolü
Tarhan Ç.
in: Pandemi ve Covid - 19, Selim Badur,Şadi Yenen, Editor, Ayrıntı Yayınları, İstanbul, pp.302-310, 2020
2016
2016Evrimsel Yeniliklerin Moleküler Temelleri
TARHAN Ç.
in: Evrimin Işığında, Altınışık N.E. ve Akış I., Editor, Yazılama, İstanbul, pp.58-70, 2016
2016
2016Epigenetics and Applications in Plants
TARHAN Ç., TURGUT KARA N.
in: Plant Omics: Trends and Applications, Hakeem, Khalid Rehman, Tombuloglu, Huseyin, Tombuloğlu, Güzin, Editor, Springer International Publishing, Zürich, pp.255-270, 2016
2013
2013Hayvanlar Ne İster (Hayvan Bilinci, Hayvan Refahı ve İnsanın Esenliği)
TARHAN Ç.
Alfa, İstanbul, 2013
2012
2012Derin Homoloji ve Evrimsel Yeniliklerin Ortaya Çıkışındaki Rolü
TARHAN Ç.
in: Evrim Sürüyor, Durmuş Z.Ö. ve Akış I., Editor, Yazılama, İstanbul, pp.103-113, 2012
Supported Projects
2022 - 2024
2022 - 2024NAA40 MUTASYONUNUN Schizosaccharomyces pombede HÜCRE YAŞLANMA MEKANİZMALARI ÜZERİNE ETKİLERİNİN İNCELENMESİ
Project Supported by Higher Education Institutions
TARHAN Ç. (Executive), ÇALICI S. Z., ÖZDEN B.
2022 - 2024
2022 - 2024NAA40 MUTASYONUNUN Schizosaccharomyces pombede HÜCRE YAŞLANMA MEKANİZMALARI ÜZERİNE ETKİLERİNİN İNCELENMESİ
Project Supported by Higher Education Institutions
Çalici S. Z., Özden B., Tarhan Ç. (Executive)
2022 - 2023
2022 - 2023Antidiyabetik İlaç Metforminin Schizosaccharomyces pombe'de Gen Anlatım Profili Üzerine Etkisi
Project Supported by Higher Education Institutions
TARHAN Ç. (Executive), MIRAJ H.
2020 - 2021
2020 - 2021Schizosaccharomyces pombe'de B-Hidroksibütirat Keton Cisimciğinin Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Project Supported by Higher Education Institutions
TARHAN Ç. (Executive), ULUDAĞ H.
2020 - 2021
2020 - 2021Schizosaccharomyces pombe'de Metformin'in Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Project Supported by Higher Education Institutions
TARHAN Ç. (Executive), ŞEYLAN C.
2016 - 2017
2016 - 2017Epigenetics and Applications in Plants
Project Supported by Higher Education Institutions
TARHAN Ç.
2016 - 2017
2016 - 2017GIDALARDA TATLANDIRICI OLARAK KULLANILAN FRUKTOZ ŞURUBUNUN HÜCRE YAŞLANMASI ÜZERİNE ETKİLERİ
Project Supported by Higher Education Institutions
KARAER UZUNER S. (Executive), ÇOBAN F., TARHAN Ç., ÖZDEMİR E.
2015 - 2017
2015 - 2017
İnsan hastalıklarının moleküler mekanizmalarının araştırılmasında Schizosaccharomyces pombe'nin model organizma olarak kullanılmasının optimizasyonu
Project Supported by Higher Education Institutions
PALABIYIK B. (Executive), YILMAZER M., TARHAN Ç., KARAER UZUNER S., ARICAN E., ÖZCAN F. G., et al.
2016 - 2016
2016 - 2016Schizosaccharomyces pombe'de Branched Chain Amico Acid Aminotransferase (Eca39) Geninin Yaşlanma Üzerindeki Etkisinin Araştırılması
Project Supported by Higher Education Institutions
KARAER UZUNER S. (Executive), ISENI T., YANIK A., TARHAN Ç.
2013 - 2016
2013 - 2016MOLEKÜLER BİYOTEKNOLOJİ LABORATUVARININ KURULMASI
Project Supported by Higher Education Institutions
ARDA E. Ş. N. (Executive), UÇARLI C., ARICAN E., ALBAYRAK G., GÜREL A. F., ARI Ş., et al.
Memberships / Tasks in Scientific Organizations
2008 - Continues
2008 - ContinuesTürk Mikrobiyoloji Derneği
Member
Congress and Symposium Activities
01 July 2009 - 01 July 2009
01 July 2009 - 01 July 2009Suna Kıraç Conferences on Neurodegeneration İstanbul Stem Cells, RNAi and Neurodegeneration
Attendee
İstanbul-Turkey
01 April 2008 - 01 April 2008
01 April 2008 - 01 April 2008New Frontiers in Understanding and Treating ALS
Attendee
İstanbul-Turkey
01 May 2004 - 01 May 2004
01 May 2004 - 01 May 2004I. Ulusal Klinik ve Pratikte Kök Hücre ve Gen Tedavisi Kongresi
Attendee
İstanbul-Turkey
Citations
Total Citations (WOS): 14
h-index (WOS): 2
Jury Memberships
July-2020
July 2020Doctoral Examination
Doctoral Examination - Bezmiâlem Vakıf Üniversitesi
September-2019
September 2019Committee Of Expert
Committee Of Expert - Istanbul University
May-2019
May 2019Doctoral Examination
Doctoral Examination - İstanbul Üniversitesi
January-2019
January 2019Post Graduate
Post Graduate - Hacettepe Üniversitesi
March-2018
March 2018