Doç. Dr. Ayşe Tarbın JANNUZZI

Yayın Ağı

Makaleler 37

1. HBV Infection Drives PSMB5-Dependent Proteasomal Activation in Humanized Mice and HBV-Associated HCC

Jannuzzı A. T., Sari G., Arslan-Eseryel S., Zeybel M., Yilmaz Y., Dayangac M., et al.

VIRUSES , cilt.17, sa.11, ss.1454, 2025 (Scopus)

2. Targeting Cancer Cell Proliferation Using Piperazine-Linked Quinolinequinones: Mechanism and Metabolic Profile

YILMAZ GÖLER A. M., JANNUZZI A. T., Biswas A., Mondal S., Basavanakatti V. N., Yildirim H., et al.

CHEMICAL BIOLOGY & DRUG DESIGN , sa.6, 2025 (SCI-Expanded)

3. Aminated Quinolinequinones With EDG(s) as a Prostate Cancer Inhibitor: Mechanistic Insights and Pharmacokinetic Limitations

JANNUZZI A. T., Yilmaz A. M., Biswas A., Mondal S., Basavanakatti V. N., YILDIRIM H., et al.

Chemistry and Biodiversity , 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

4. Prospects for Prostate Cancer Chemotherapy: Cytotoxic Evaluation and Mechanistic Insights of Quinolinequinones with ADME/PK Profile

JANNUZZI A. T., YILMAZ GÖLER A. M., Biswas A., Mondal S., Basavanakatti V. N., YILDIRIM H., et al.

Biomedicines , cilt.12, sa.6, 2024 (SCI-Expanded)

5. Synergistic role of thymoquinone and 5-fluorouracil in U-251MG glioblastoma cell line

Mutlu Altundag E., Jannuzzı A. T., Ozbilenler C., Usturk S., Altinoglu G.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.49, sa.1, ss.82-89, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

6. Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling

JANNUZZI A. T., YILMAZ GÖLER A. M., Shilkar D., Mondal S., Basavanakatti V. N., Yildirim H., et al.

CHEMICAL BIOLOGY & DRUG DESIGN , cilt.102, sa.5, ss.1133-1154, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

7. Analysis of Quinolinequinone Analogs with Promising Cytotoxic Activity against Breast Cancer

YILMAZ GÖLER A. M., Tarbin Jannuzzi A. T., Biswas A., Mondal S., Basavanakatti V. N., Jayaprakash Venkatesan R., et al.

CHEMISTRY & BIODIVERSITY , cilt.20, sa.9, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

8. Molecular Cardiotoxic Effects of Proteasome Inhibitors Carfilzomib and Ixazomib and Their Combination with Dexamethasone Involve Mitochondrial Dysregulation

Jannuzzı A. T., Korkmaz N. S., Günaydın Akyıldız A., Arslan Eseryel S., Karademir Yilmaz B., Alpertunga B.

Cardiovascular Toxicology , cilt.23, sa.3-4, ss.121-131, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

9. Ubiquitin proteasomal system is a potential target of the toxic effects of organophosphorus flame retardant triphenyl phosphate

JANNUZZI A. T., YILMAZ GÖLER A. M., Alpertunga B.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY , cilt.96, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

10. In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells

Goler A. M. Y., JANNUZZI A. T., Bayrak N., Yildiz M., Yildirim H., Otsuka M., et al.

ACS OMEGA , cilt.7, sa.34, ss.30250-30264, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

11. Zoledronic acid-induced oxidative damage and endoplasmic reticulum stress-mediated apoptosis in human embryonic kidney (HEK-293) cells

Kara M., Boran T., Öztaş E., Jannuzzi A. T., Özden S., Özhan G.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , cilt.36, sa.8, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

JANNUZZI A. T., Goler A. M. Y., Bayrak N., Yildiz M., Yildirim H., Yilmaz B. K., et al.

PHARMACEUTICALS , cilt.15, sa.7, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

13. Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

Yıldırım H., Yıldız M., Bayrak N., Mataracı-Kara E., Radwan M. O., Jannuzzi A. T., et al.

PHARMACEUTICALS , cilt.15, sa.5, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

14. Determination of the Phototoxicity Potential of Commercially Available Tattoo Inks Using the 3T3-neutral Red Uptake Phototoxicity Test

Utku Turk E. G., Jannuzzi A. T., Alpertunga B.

Turkish journal of pharmaceutical sciences , cilt.19, sa.1, ss.70-75, 2022 (ESCI)

15. Eugenol aggravates UVA-induced cytotoxic and genotoxic response in HaCaT human keratinocytes

JANNUZZI A. T.

Journal of Research in Pharmacy , cilt.26, sa.2, ss.354-361, 2022 (ESCI)

16. Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells

JANNUZZI A. T., Yildiz M., Bayrak N., Yildirim H., Shilkar D., Jayaprakash V., et al.

CHEMICO-BIOLOGICAL INTERACTIONS , cilt.349, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

17. Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib.

Akyildiz A. G., Boran T., Jannuzzi A. T., Alpertunga B.

Toxicology and applied pharmacology , cilt.423, ss.115577, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

18. Proteasomal System Related Stress Response in Different Cancer Cell Lines

Jannuzzi A. T., Arslan S., Alpertunga B., Yilmaz B. K.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES , cilt.11, sa.1, ss.28-33, 2021 (ESCI) Sürdürülebilir Kalkınma

19. Synergistic Induction of Apoptosis by Quercetin and Curcumin in Chronic Myeloid Leukemia (K562) Cells: II. Signal Transduction Pathways Involved.

Mutlu Altundağ E., Yılmaz A. M., Sert Serdar B., Jannuzzi A. T., Koçtürk S., Yalçın A. S.

Nutrition and cancer , cilt.73, ss.703-712, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

20. Extended regorafenib treatment can be linked with mitochondrial damage leading to cardiotoxicity.

Boran T., Akyildiz A., Jannuzzi A. T., Alpertunga B.

Toxicology letters , cilt.336, ss.39-49, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

21. Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

Can N. D., Basturk E., Kizilboga T., Akçay İ. M., Dingiloglu B., Tatli O., et al.

PLOS ONE , cilt.16, sa.8, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

22. In vitro assessment of the cytotoxic, genotoxic and oxidative stress effects of the synthetic cannabinoid JWH-018 in human SH-SY5Y neuronal cells.

Sezer Y., Jannuzzi A. T., Huestis M. A., Alpertunga B.

Toxicology research , cilt.9, ss.734-740, 2020 (SCI-Expanded)

23. Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib.

Jannuzzi A. T., Arslan S., Yilmaz A., Sari G., Beklen H., Méndez L., et al.

Redox biology , cilt.32, ss.101502, 2020 (SCI-Expanded)

24. Discovery of a new family of heterocyclic amine linked plastoquinone analogs for antimicrobial evaluation

Tuyun A. F., Yildiz M., Bayrak N., Yildirim H., Kara E., Jannuzzi A. T., et al.

DRUG DEVELOPMENT RESEARCH , cilt.80, sa.8, ss.1098-1109, 2019 (SCI-Expanded)

25. Celastrol pretreatment as a therapeutic option against cisplatin-induced nephrotoxicity

Boran T., Gunaydin A., Jannuzzi A. T., Ozcagli E., Alpertunga B.

TOXICOLOGY RESEARCH , cilt.8, sa.5, ss.723-730, 2019 (SCI-Expanded)

26. In-Vitro Investigation of the Cytotoxic and Genotoxic Effects of Benzimidazole Group Pesticides Benomyl and Carbendazim

KARA M., JANNUZZI A. T., Yön Ş.

HSOA Journal of Toxicology: Current Research , sa.3, ss.1-6, 2019 (Hakemli Dergi)

27. Investigation of Antimicrobial, Antibiofilm, and Cytotoxic Effects of Straight-Chained Sulfanyl Members of Arylamino-1,4-naphthoquinones as Potential Antimicrobial Agents

MATARACI KARA E., JANUZZI A. T., BAYRAK N., YILDIRIM H., YILDIZ M., TUYUN A. F., et al.

European Journal of Biology , cilt.78, sa.2, ss.117-123, 2019 (Scopus) Sürdürülebilir Kalkınma

28. Jannuzzi, A. T., Sari, G., Yilmaz, A. M., Karademir, B., & Alpertunga, B. (2018). Proteasomal Inhibition with Bortezomib Causes Selective Autophagy Upregulation and Perinuclear Clustering of Mitochondria in Human Neuronal Cells.

JANNUZZI A. T., Sarı G., Yılmaz A. M., Karademir B., ALPERTUNGA B.

MDPI Proceedings , cilt.2, sa.25, ss.1-5, 2018 (Hakemli Dergi)

29. Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Karademir B., Sari G., Jannuzzi A. T., Musunuri S., Wicher G., GRUNE T., et al.

SCIENTIFIC REPORTS , cilt.8, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

30. Celastrol ameliorates acetaminophen-induced oxidative stress and cytotoxicity in HepG2 cells

Jannuzzi A. T., Kara M., Alpertunga B.

HUMAN & EXPERIMENTAL TOXICOLOGY , cilt.37, sa.7, ss.742-751, 2018 (SCI-Expanded)

31. İlaçlar İle İndüklenen Fosfolipidozis ve Katyonik Amfifilik İlaçlar

BORAN T., JANNUZZI A. T., ALPERTUNGA B.

Hacettepe University Journal of the Faculty of Pharmacy , cilt.38, sa.2, ss.65-75, 2018 (Hakemli Dergi)

32. Evaluation of DNA damage and DNA repair capacity in occupationally lead-exposed workers

Jannuzzi A. T., Alpertunga B.

TOXICOLOGY AND INDUSTRIAL HEALTH , cilt.32, sa.11, ss.1859-1865, 2016 (SCI-Expanded)

33. Using Stem Cells in Toxicological Assessments

JANNUZZI A. T., ÖZÇAĞLI E., Kovatsi L., Goumenou M., Tsatsakis A. M.

Journal of Medical Toxicology and Clinical Forensic Medicine , cilt.2, sa.15, ss.1-2, 2016 (Hakemsiz Dergi)

34. Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer

Jannuzzi A. T., Karaman E., Oztas E., Yanar H. T., Ozhan G.

GENETIC TESTING AND MOLECULAR BIOMARKERS , cilt.19, sa.12, ss.692-697, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

35. Investigation on the toxic potential of Tribulus terrestris in vitro.

Abudayyak M. F., Jannuzzi A. T., Ozhan G., Alpertunga B.

Pharmaceutical biology , cilt.53, sa.4, ss.469-76, 2015 (SCI-Expanded, Scopus)

36. VEGF Gene Polymorphisms and Susceptibility to Colorectal Cancer

Jannuzzi A. T., Ozhan G., Yanar H. T., Alpertunga B.

GENETIC TESTING AND MOLECULAR BIOMARKERS , cilt.19, sa.3, ss.133-137, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

37. Oxidative stress mediated cardiac apoptosis

Kara M., Ozcagli E., Jannuzzi A. T., Alpertunga B.

ISTANBUL JOURNAL OF PHARMACY , cilt.45, sa.2, ss.217-232, 2015 (ESCI) Sürdürülebilir Kalkınma

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 26

1. REGULATION OF THE UBIQUITIN-PROTEASOME SYSTEM AND PROTEOSTASIS WITH MTOR INHIBITION IN CYTOCHROME C OXIDASE DEFICIENCY

JANNUZZI A. T., Giacchin G., Balmaceda V., Viscomi C.

Annual Meeting of the Society-for-Free-Radical-Research-Europe (SFRR-E), İstanbul, Türkiye, 5 - 07 Haziran 2024, ss.41, (Özet Bildiri)

2. Identification of Plastoquinone Analogs To Be Effective in Breast Cancer Treatment

Tuyun A. F., Bayrak N., Yıldız M., Yıldırım H., Jannuzzı A. T., Shilkar D., et al.

EFMC-ASMC International Symposium on Advances in Synthetic and Medicinal Chemistry, Zagreb, Hırvatistan, 3 - 07 Eylül 2023, ss.250, (Özet Bildiri)

3. Evaluation of cytotoxic activity of small aminated quinolinequinones in vitro as anti-cancer molecules

Jannuzzı A. T., Yılmaz Göler A. M., Tuyun A. F.

8th International Electronic Conference on Medicinal Chemistry , 1 - 30 Kasım 2022, ss.65803, (Özet Bildiri)

4. Thymoquinone and 5-fluorouracil combinational effect on cell viability and ROS production in glioblastoma cells

Mutlu Altundağ E., Jannuzzı A. T.

4th International Eurasian Conference on Biological and Chemical Sciences, İstanbul, Türkiye, 24 Kasım 2021 - 26 Şubat 2022, ss.81, (Özet Bildiri)

5. In vitro evaluation of toxic effecs of synthetic cannabinoid EG-018 in H9c2 cardiomyocytes

Jannuzzı A. T.

3rd International Industrial and Environmental Toxicology Congress, İstanbul, Türkiye, 4 - 10 Kasım 2021, ss.58, (Özet Bildiri)

6. Combinational effect of cisplatin and celastrol on the proliferation and apoptosis of A549 human lung adenocarcinoma cells

Jannuzzı A. T., Mutlu Altundağ E., Alpertunga B.

6. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi, Ankara, Türkiye, 10 - 11 Nisan 2021, ss.31, (Özet Bildiri)

7. Cardiotoxicity Induced by Tyrosine Kinase Inhibitors

Günaydın A., BORAN T., JANNUZZI A. T., ALPERTUNGA B.

10th International congress of the Turkish Society of Toxicology, Antalya, Türkiye, 16 - 19 Ekim 2019, ss.72, (Tam Metin Bildiri)

8. Mitochondrial Alterations May Play a Role in Cardiotoxicity of the Tyrosine Kinase Inhibitor Regorafenib

BORAN T., Günaydın A., JANNUZZI A. T., ALPERTUNGA B.

SOT 2019 58th Annual Meeting & ToxExpo, Baltimore, Amerika Birleşik Devletleri, 10 - 14 Mart 2019, ss.252, (Tam Metin Bildiri)

9. In vitro Investigation of the Antineoplastic Agent Lenvatinib Induced Cardiotoxicity in Terms of Mitochondrial Toxicity

Günaydın A., BORAN T., JANNUZZI A. T., ALPERTUNGA B.

SOT 2019 58th Annual Meeting & ToxExpo, Baltimore, Amerika Birleşik Devletleri, 10 - 14 Mart 2019, ss.252, (Tam Metin Bildiri)

10. Proteomic Analysis Links Proteasome Inhibitors Induced Peripheral Neuropathy to Mitochondrial Toxicity in a Human Neuronal Cell Model

JANNUZZI A. T., Sarı G., Yılmaz A. M., Fedorova M., Karademir B., ALPERTUNGA B.

SOT 58th Annual Meeting, Baltimore, Amerika Birleşik Devletleri, 10 - 14 Mart 2019, ss.81, (Tam Metin Bildiri)

11. Sağlık Kuruluşlarından Kaynaklanan Atıksuların Toksisite Açısından Değerlendirilmesi: Cerrahpaşa Tıp Fakültesi Örneği

Jannuzzı A. T., Özhan G.

4. Ulusal Sağlık Kuruluşlarında Çevre Yönetimi Sempozyumu, İstanbul, Türkiye, 24 - 25 Ekim 2018, (Tam Metin Bildiri)

12. Proteomic analysis of bortezomib or carfilzomib treated human neural cells for identification of potential pathways of neurotoxicity

JANNUZZI A. T., Sarı G., Fedorova M., Karademir B., ALPERTUNGA B.

FEBS 2018 Advanced Course-Redox-omic Technologies and their Application in Health and Disease, Spetses, Yunanistan, 17 - 23 Eylül 2018, (Tam Metin Bildiri)

13. Comparative effects of bortezomib and carfilzomib in co-culture of human neural progenitor cells and leukemia cells

Jannuzzi A. T., Arslan S., Yilmaz A. M., Alpertunga B., Karademir B.

19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI), Lisbon, Portekiz, 01 Ocak 2018, cilt.120, (Özet Bildiri)

14. Assessing the role of celastrole on cisplatin induced nephrotoxicity under in vitro conditions

Boran T., Gunaydin A., Jannuzzi A. T., Ozcagli E., Alpertunga B.

53rd Congress of the European-Societies-of-Toxicology (EUROTOX), Bratislava, Slovakya, 10 - 13 Eylül 2017, cilt.280, (Özet Bildiri)

15. Benzimidazol Grubu Pestisitlerden Benomil ve Metaboliti Karbendazim’in Sitotoksik ve Genotoksik Etkilerinin İnVitro Koşullarda Araştırılması

Yön Ş., KARA M., ÖZÇAĞLI E., JANNUZZI A. T., ALPERTUNGA B.

3. Uluslararası İlaç ve Eczacılık Kongresi, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.761, (Tam Metin Bildiri)

Kitaplar 1

1. Istanbul Üniversitesi Eczacılık Fakültesi Ögrenci Rehberi

Cevher E. (Editör), Özhan G. (Editör), Yılmaz Özden T. (Editör), Şen Utsukarçi B. (Editör), Gürdal Abamor M. B. (Editör), Mataracı Kara E. (Editör), et al.

Istanbul University, İstanbul, 2019

Metrikler

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Yayın (Scopus)

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309

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365

H-İndeks (Scopus)

Atıf (Sobiad)

H-İndeks (Sobiad)

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