Announcements & Documents
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Education
2001 - 2007
2001 - 2007Doctorate
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri, Turkey
1998 - 2001
1998 - 2001Postgraduate
Gazi University, Eczacılık Fakültesi, Farmasötik Toksikoloji Anabilim Dalı, Turkey
1994 - 1998
1994 - 1998Undergraduate
Ankara University, Eczacılık Fakültesi, Turkey
Dissertations
2007
2007Doctorate
Human papillomavirus (HPV) pozitif bireylerde DNA onarım kapasitesinin ve genotoksik etkinin araştırılması
Gazi University, Eczacılık Fakültesi, Farmasötik Toksikoloji Anabilim Dalı
2001
2001Postgraduate
Kurşuna maruz akü fabrikası işçilerinde genotoksik hasarın challenge tekniği ile araştırılması
Gazi University, Eczacılık Fakültesi, Farmasötik Toksikoloji Anabilim Dalı
Certificates, Courses and Trainings
2014
2014Pharmacovigilance Audits & Inspections
Education Management and Planning
Quality Academy
2013
2013EUROTOX Advanced Toxicology Course 2013
Education Management and Planning
EUROTOX
2013
2013Course in Cancer Risk Assessment
Education Management and Planning
Institute of Environmental Medicine, Karolinska Institutet
2013
2013Toksisite Test Sistemleri Eğitim Programı “Ames test, Umu-C test, MTT test, YES test”
Education Management and Planning
Istanbul Universitesi Eczacılık Fakültesi
2009
2009Introduction to Good Clinical Practice-Basics of GCP implementation in clinical trials”
Education Management and Planning
Vienna School of Clinical Research
2008
2008Pharmacovigilance and Medical Product Safety,Patient safety–a shared responsibility
Education Management and Planning
Vienna School of Clinical Research
2008
2008Farmakovijilans Eğitim ve Sertifikasyon kursu
Education Management and Planning
T.C. Sağlık Bakanlığı
2006
2006Genom Bilimi Kursu
Education Management and Planning
Ankara Üniversitesi Biyoteknoloji Enstitüsü
2006
2006Genom Bilimi Kursu
Education Management and Planning
Ankara Üniversitesi Biyoteknoloji Enstitüsü
2006
2006İleri Işık Mikroskopi Kursu
Education Management and Planning
Ankara Üniversitesi Biyoteknoloji Enstitüsü
2005
2005Proteom Analizleri ve Uygulama Alanları
Education Management and Planning
Ankara Üniversitesi Biyoteknoloji Enstitüsü
1999
1999"Principles of Risk Assessment"
Education Management and Planning
EUROTOX
Research Areas
Medicine
Health Sciences
Internal Medicine Sciences
Pharmacology and Clinical Pharmacology
Medical Pharmacology and Toxicology
Academic Positions
2017 - Present
2017 - PresentAssociate Professor
Istanbul University, Faculty of Pharmacy , Farmasötik Toksikoloji Anabilim Dalı
2016 - 2018
2016 - 2018Assistant Professor
Istanbul University, Faculty of Pharmacy , Department of Professional Pharmaceutical Sciences
2013 - 2016
2013 - 2016Lecturer PhD
Istanbul University, Faculty of Pharmacy , Department of Professional Pharmaceutical Sciences
1998 - 2007
1998 - 2007Research Assistant
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Non Academic Experience
2009 - 2013
2009 - 2013EU-Risk Management Plan Coordinator for Gastrointestinal Group Products (Global role))
Company, AstraZeneca Pharmaceuticals , EU-Risk Management Plan Coordinator for Gastrointestinal Group Products (Global role))
2009 - 2013
2009 - 2013Avrupa Birliği-Gastrointestinal Grup İlaçları Risk Yönetim Planı Koordinatörü
Astrazeneca Ilac Sanayi Ve Ticaret Ltd Sti, Avrupa Birliği-Gastrointestinal Grup İlaçları Risk Yönetim Planı Koordinatörü
2007 - 2013
2007 - 2013Drug Safety Manager
Company, AstraZeneca Pharmaceuticals , Drug Safety Manager
Supervised Theses
2019
2019Postgraduate
The effect of CYP2C19 gene Polymorphism and cost-result analysis in stroke events observed after clopidogrel use
Özçağlı E. (Advisor)
E.Aksan(Student)
Articles
2025
20251. Exploring the anti-inflammatory activity of boron compounds through the miR-21/PTEN/AKT pathway in cecal ligation and puncture-induced sepsis
Sevim Ç., ÖZKARACA M., KARA M., TAGHIZADEHGHALEHJOUGHI A., GENÇ S., Yeni Y., et al.
Molecular Medicine Reports
, vol.31, no.2, 2025 (SCI-Expanded)
2025
20252. What are the effects of whole blood storage conditions on comet assay in terms of DNA damage and repair?
ÖZÇAĞLI E., Yesilcimen E. S., OMURTAG G. Z.
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.902, 2025 (SCI-Expanded)
2024
20243. Investigation of the miRNA levels changes to acceptable daily intake dose pesticide mixture exposure on rat mesentery and pancreas
Sevim C., Tsatsakis A., TAGHIZADEHGHALEHJOUGHI A., ÖZKARACA M., KARA M., GENÇ S., et al.
Chemosphere
, vol.349, 2024 (SCI-Expanded)
2024
20244. Addressing chemically-induced obesogenic metabolic disruption: selection of chemicals for in vitro human PPARα, PPARγ transactivation, and adipogenesis test methods
Ozcagli E., Kubickova B., Jacobs M. N.
FRONTIERS IN ENDOCRINOLOGY
, vol.15, 2024 (SCI-Expanded)
2023
20235. DNA Damage Estimation after Chronic and Combined Exposure to Endocrine Disruptors: An In Vivo Real-Life Risk Simulation Approach
Karzi V., Ozcagli E., Tzatzarakis M. N., Vakonaki E., Fragkiadoulaki I., Kalliantasi A., et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
, no.12, 2023 (SCI-Expanded)
2023
20236. Human Biomonitoring of Trace Elements (Zn, Cu, Mn, Cd and As) Level in a Healthy Urban Population in Türkiye
Soylemez E., ÖZÇAĞLI E., Goktas E. F., Kurekci F., OMURTAG G. Z.
Journal of Research in Pharmacy
, vol.27, no.5, pp.2087-2094, 2023 (ESCI)
2022
20227. The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
Soylemez E., Ozcagli E., Korkmaz S., Tok O. E., Aydin M. S., Omurtag G. Z.
TOXICOLOGY AND INDUSTRIAL HEALTH
, vol.38, pp.70-79, 2022 (SCI-Expanded)
2021
20218. Determination of Genotype Distribution and Allele Frequencies of XRCC1 (Arg399Gln) and XRCC3 (Thr241Met) Polymorphisms in Turkish Population.
Söylemez E., Özçağlı E., Omurtag G. Z.
Ankara Üniversitesi Tıp Fakültesi Mecmuası , vol.74, no.Suppl. 1, pp.65-71, 2021 (Peer-Reviewed Journal)
2021
20219. Porphyridium purpureum microalga physiological and ultrastructural changes under copper intoxication
Markina Z., Orlova T. Y., Vasyanovich Y. A., Vardavas A., Stivaktakis P. D., Vardavas C., et al.
TOXICOLOGY REPORTS
, vol.8, pp.988-993, 2021 (ESCI)
2019
201910. Celastrol pretreatment as a therapeutic option against cisplatin-induced nephrotoxicity
Boran T., Gunaydin A., Jannuzzi A. T., Ozcagli E., Alpertunga B.
TOXICOLOGY RESEARCH
, vol.8, no.5, pp.723-730, 2019 (SCI-Expanded)
2019
201911. CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels
RAY B., Ozcagli E., Sadee W., Wang D.
PHARMACOGENETICS AND GENOMICS
, vol.29, no.2, pp.39-47, 2019 (SCI-Expanded)
2018
201812. Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging
Ozcagli E., Kara M., Kotil T., Fragkiadaki P., Tzatzarakis M. N., TSITSIMPIKOU C., et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
, vol.42, no.1, pp.405-413, 2018 (SCI-Expanded)
2018
201813. Effects of stanozolol on apoptosis mechanisms and oxidative stress in rat cardiac tissue
Kara M., Ozcagli E., Kotil T., Alpertunga B.
STEROIDS
, vol.134, pp.96-100, 2018 (SCI-Expanded)
2018
201814. How Does Infection with Human Papillomavirus 16 and 18 Impact on DNA Damage and Repair in Cervical Cells and Peripheral Blood?
Ozcagli E., Biri A., Dinc B., Sardas S.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, vol.22, no.5, pp.332-336, 2018 (SCI-Expanded)
2018
201815. The metabolism of imidacloprid by aldehyde oxidase contributes to its clastogenic effect in New Zealand rabbits
Vardavas A. I., Ozcagli E., Fragkiadaki P., Stivaktakis P. D., Tzatzarakis M. N., Alegakis A. K., et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
, vol.829, pp.26-32, 2018 (SCI-Expanded)
2017
201716. Worldwide legislative challenges related to psychoactive drugs
NEGREI C., GALATEANU B., STAN M., BALALAU C., DUMITRU M. L. B., Ozcagli E., et al.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.25, 2017 (SCI-Expanded)
2017
201717. A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective
WOJCIECHOWSKI V. V., CALINA D., TSAROUHAS K., PIVNIK A. V., SERGIEVICH A. A., KODINTSEV V. V., et al.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
, vol.25, 2017 (SCI-Expanded)
2017
201718. Determination of DNA damage and telomerase activity in stanozolol-treated rats
Kara M., Ozcagli E., Fragkiadaki P., Kotil T., Stivaktakis P. D., Spandidos D. A., et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
, vol.13, no.2, pp.614-618, 2017 (SCI-Expanded)
2016
201619. The role of oxidative DNA damage and GSTM1, GSTT1, and hOGG1 gene polymorphisms in coronary artery disease risk
Kadioglu E., Tacoy G., Ozcagli E., Okyay K., AKBOGA M. K., Cengel A., et al.
ANATOLIAN JOURNAL OF CARDIOLOGY
, vol.16, no.12, pp.931-938, 2016 (SCI-Expanded)
2016
201620. Using Stem Cells in Toxicological Assessments
JANNUZZI A. T., ÖZÇAĞLI E., Kovatsi L., Goumenou M., Tsatsakis A. M.
Journal of Medical Toxicology and Clinical Forensic Medicine , vol.2, no.15, pp.1-2, 2016 (Non Peer-Reviewed Journal)
2016
201621. Molecular biomarkers of oxidative stress and role of dietary factors in gasoline station attendants
Costa C., Ozcagli E., Gangemi S., Schembri F., Giambo F., Androutsopoulos V., et al.
FOOD AND CHEMICAL TOXICOLOGY
, vol.90, pp.30-35, 2016 (SCI-Expanded)
2016
201622. Long-term exposure of rabbits to imidaclorpid as quantified in blood induces genotoxic effect
Stivaktakis P. D., Kavvalakis M. P., Tzatzarakis M. N., Alegakis A. K., Panagiotakis M. N., Fragkiadaki P., et al.
CHEMOSPHERE
, vol.149, pp.108-113, 2016 (SCI-Expanded)
2016
201623. Effects of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites on DNA damage and repair under in vitro conditions
Ozcagli E., Alpertunga B., FENGA C., Berktas M., TSITSIMPIKOU C., Wilks M. F., et al.
FOOD AND CHEMICAL TOXICOLOGY
, vol.89, pp.1-7, 2016 (SCI-Expanded)
2016
201624. Cardiotoxicity in rabbits after long-term nandrolone decanoate administration
Vasilaki F., TSITSIMPIKOU C., TSAROUHAS K., GERMANAKIS I., Tzardi M., Kavvalakis M., et al.
TOXICOLOGY LETTERS
, vol.241, pp.143-151, 2016 (SCI-Expanded)
2015
201525. Antioxidant, Antimicrobial, Cytotoxic and Anticholinesterase Activities of Seven Mushroom Species with their Phenolic Acid Composition
DUNDAR A., OKUMUŞ V., OZDEMIR S., CELIK K. S., BOGA M., ÖZÇAĞLI E., et al.
Journal of Horticulture , vol.2, no.4, pp.1-7, 2015 (Peer-Reviewed Journal)
2015
201526. Biosimilar Drugs and Pharmacovigilance
ÖZÇAĞLI E., ALPERTUNGA B., Tsatsakis A. M.
Pharm Anal Acta , vol.6, no.416, pp.1, 2015 (Peer-Reviewed Journal)
2015
201527. Oxidative stress mediated cardiac apoptosis
Kara M., Ozcagli E., Jannuzzi A. T., Alpertunga B.
ISTANBUL JOURNAL OF PHARMACY
, vol.45, no.2, pp.217-232, 2015 (ESCI)
2015
201528. Risk assessment for children exposed to DDT residues in various milk types from the Greek market
TSAKIRIS I. N., GOUMENOU M., Tzatzarakis M. N., Alegakis A. K., TSITSIMPIKOU C., Ozcagli E., et al.
FOOD AND CHEMICAL TOXICOLOGY
, vol.75, pp.156-165, 2015 (SCI-Expanded)
2014
201429. Cd, Pb and Hg Biomonitoring in Fish of the Mediterranean Region and Risk Estimations on Fish Consumption
Renieri E. A., Alegakis A. K., Kiriakakis M., Vinceti M., Özçağlı E., Wilks M. F., et al.
TOXICS
, vol.2, no.3, pp.417-442, 2014 (ESCI)
2012
201230. Assessment of Individual Susceptibility to Baseline DNA and Cytogenetic Damage in a Healthy Turkish Population: Evaluation with Lifestyle Factors
Kadıoğlu E., Kocabas N. A., Demircigil G. C., Coskun E., ÖZÇAĞLI E., Durmaz E., et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS
, vol.16, no.10, pp.1157-1164, 2012 (SCI-Expanded)
2009
200931. Assessment of Genotoxic Damage in Nurses Occupationally Exposed to Anaesthetic Gases or Antineoplastic Drugs by the Comet Assay
İzdeş S., Şardaş S., Kadıoğlu E., Kaymak Ç., ÖZÇAĞLI E.
JOURNAL OF OCCUPATIONAL HEALTH
, vol.51, no.3, pp.283-286, 2009 (SCI-Expanded)
2008
200832. Oxidative DNA damage and total antioxidant status in rats during experimental gram-negative sepsis
Kaymak Ç., Kadıoğlu E., ÖZÇAĞLI E., Osmanoğlu G., İzdeş S., Ağalar C., et al.
HUMAN & EXPERIMENTAL TOXICOLOGY
, vol.27, no.6, pp.485-491, 2008 (SCI-Expanded)
2006
200633. Mercury exposure in dental practice
Ateşağaoğlu A., Omurlu H., Ozcagli E., Şardaş S., Ertaş N.
OPERATIVE DENTISTRY
, vol.31, no.6, pp.666-669, 2006 (SCI-Expanded)
2006
200634. The role of antioxidant supplementation in occupational exposure to waste anaesthetic gases
Sardas S., Izdes S., ÖZÇAĞLI E., Kanbak O., Kadioglu E.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
, vol.80, no.2, pp.154-159, 2006 (SCI-Expanded)
2005
200535. Assessment of DNA damage in postmenopausal women under hormone replacement therapy
Ozcagli E., Sardas S., Biri A.
MATURITAS
, vol.51, no.3, pp.280-285, 2005 (SCI-Expanded)
2005
200536. Assessment of abnormal DNA repair responses and genotoxic effects in lead exposed workers
Karakaya A. E., ÖZÇAĞLI E., Ertaş N., Şardaş S.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
, vol.47, no.4, pp.358-363, 2005 (SCI-Expanded)
2004
200437. Assessment of DNA damage in glue sniffers by use of the alkaline comet assay
Çok İ., Şardaş S., Kadıoğlu E., ÖZÇAĞLI E.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
, vol.557, no.2, pp.131-136, 2004 (SCI-Expanded)
2002
200238. Assessment of DNA damage in women using oral contraceptives
Biri A., CİVELEK E., Karahalil B., Şardaş S.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
, vol.521, pp.113-119, 2002 (SCI-Expanded)
2002
200239. Chromosomal aberrations under basal conditions and after treatment with X-ray in human lymphocytes as related to the GSTM1 genotype
Karahalil B., Şardaş S., Kocabas N., Alhayıroğlu E., Karakaya A., CİVELEK E.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
, vol.515, pp.135-140, 2002 (SCI-Expanded)
Papers Presented at Peer-Reviewed Scientific Conferences
2018
20181. A systematic Review of Assessment Approaches in Pharmacoeconomic Analyses in Turkey.
ÖZÇAĞLI E., Aksan E.
10th Congress of Toxicology in Developing Countires (CTDC10) and 12th Congress of the Serbian Society of Toxicology (12thSCT), Belgrad, Serbia And Montenegro, 18 - 21 April 2018, pp.169, (Full Text)
2017
20172. Assessing the role of celastrole on cisplatin induced nephrotoxicity under in vitro conditions
Boran T., Gunaydin A., Jannuzzi A. T., Ozcagli E., Alpertunga B.
53rd Congress of the European-Societies-of-Toxicology (EUROTOX), Bratislava, Slovakia, 10 - 13 September 2017, vol.280, (Summary Text)
2017
20173. Determination of Stanolozol's Effects on Apoptosis Mechanism via Oxidative Stress in Rat Cardiac Tissue
Kara M., Özçağlı E., Kotil T., Alpertunga B.
ATAVET 1.Uluslararası Katılımlı Öğrenci Kongresi, Erzurum, Turkey, 18 - 20 October 2017, pp.1, (Summary Text)
2017
20174. Evaluation of tumorogenic proteins in stanozolol treated rat kidney
Kotil T., Sevim Ç., Kara M., Özçağlı E., Alpertunga B.
13th Multinational Congress on Microscopy, Pula, Croatia, 24 - 29 September 2017, pp.387-389, (Summary Text)
2017
20175. Benzimidazol Grubu Pestisitlerden Benomil ve Metaboliti Karbendazim’in Sitotoksik ve Genotoksik Etkilerinin İnVitro Koşullarda Araştırılması
Yön Ş., KARA M., ÖZÇAĞLI E., JANNUZZI A. T., ALPERTUNGA B.
3. Uluslararası İlaç ve Eczacılık Kongresi, İstanbul, Turkey, 26 - 29 April 2017, pp.761, (Full Text)
2017
20176. Immunohistochemistry analysis and TERT- PTEN protein expressions in Stanozolol exposure.
Özçağlı E., Kara M., Kotil T., Alpertunga B.
The Society of Toxicology 56th Annual Meeting in Baltimore, Maryland, ABD., Maryland, United States Of America, 12 - 16 March 2017, pp.153, (Summary Text)
2016
20167. DNA damage after long-term exposure of rabbits to Imidacloprid and sodium tungstate
Vardavas A. I., Ozcagli E., Fragkiadaki P., Stivaktakis P. D., Tzatzarakis M. N., Kaloudis K., et al.
52nd Congress of the European-Societies-of-Toxicology (EUROTOX), Sevilla, Spain, 4 - 07 September 2016, vol.258, (Summary Text)
2016
20168. Effects of supraphysiological stanozolol administration on cardiac apoptosis
Kara M., Ozcagli E., Kotil T., Alpertunga B.
52nd Congress of the European-Societies-of-Toxicology (EUROTOX), Sevilla, Spain, 4 - 07 September 2016, vol.258, (Summary Text)
2016
20169. Pharmacovigilance activities in children
ÖZÇAĞLI E., ALPERTUNGA B.
The Society of Toxicology 55th Annual Meeting,, New Orleans, United States Of America, 13 - 17 March 2016, pp.150, (Full Text)
2015
201510. EFFECTS OF STANOZOLOL ON OXIDATIVE STRESS PARAMETERS
KARA M., ÖZÇAĞLI E., ALPERTUNGA B.
TURKHELTOX 2015, İzmir, Turkey, 21 - 24 October 2015, pp.1, (Full Text)
2015
201511. Web 2.0 platforms and their impact on pharmacovigilance
Vynias D., ÖZÇAĞLI E.
TURKHELTOX15, İzmir, Turkey, 21 - 24 October 2015, (Full Text)
2015
201512. Oxidative stress and telomerase activity in PBMCs after long term exposure of rabbits to cypermethrin and piperonyl butoxide
Vardavas A. I., Fragkiadaki P., Tsiaoussis J., Ozcagli E., Stagkos D., Kouretas D., et al.
51st Congress of the European-Societies-of-Toxicology (EUROTOX), Porto, Portugal, 13 - 16 September 2015, vol.238, (Summary Text)
2015
201513. Oxidative stress and telomerase activity in blood and heart tissue in long-term exposed rabbits to nandrolone decanoate
Vasilaki F., Tsitsimpikou C., Tsarouhas K., Fragkiadaki P., Kalogeraki A., Stagkos D., et al.
51st Congress of the European-Societies-of-Toxicology (EUROTOX), Porto, Portugal, 13 - 16 September 2015, vol.238, (Summary Text)
2015
201514. Past, present and future of pharmacovigilance: An update for current aspect
Ozcagli E.
51st Congress of the European-Societies-of-Toxicology (EUROTOX), Porto, Portugal, 13 - 16 September 2015, vol.238, (Summary Text)
2015
201515. Biosimilar drugs and pharmacovigilance
ÖZÇAĞLI E., ALPERTUNGA B.
International Symposium of Advances in Predictive & Personalized Medicine “Bridging the nations in Istanbul: Personalized & Predictive Medicine in Turkey, İstanbul, Turkey, 2 - 03 April 2015, pp.24, (Full Text)
2015
201516. Assessment of Risk Management Approaches in Orphan Drugs.
ÖZÇAĞLI E., TUT B. D., ALPERTUNGA B.
International Symposium of Advances in Predictive & Personalized Medicine “Bridging the nations in Istanbul: Personalized & Predictive Medicine in Turkey, İstanbul, Turkey, 2 - 03 April 2015, pp.25, (Full Text)
2014
201417. Evaluation of DNA damage in NRK 52E cells following in vitro treatment of 3-MCPD and its metabolites
Ozcagli E., Alpertunga B.
50th Congress of the European-Societies-of-Toxicology, Edinburgh, Saint Helena, 7 - 10 September 2014, vol.229, (Summary Text)
2014
201418. Biochemical markers in long-term exposed rabbits to nandrolone decanoate
Vasilaki F., Tsitsimpikou C., Tsarouhas K., ÖZÇAĞLI E., Fragkiadaki P., Heretis I., et al.
50th Congress of European Societies of Toxicology EUROTOX-2014, Edinburgh, United Kingdom, 7 - 10 September 2014, vol.229S, (Full Text)
2012
201219. Determination of DNA damage in women using Raloxifene.
ÖZÇAĞLI E., Şardaş S., Biri A., Çiftçi B., Korucuoğlu U., Gürsoy R.
6th International Congress of Turkish Society of Toxicology, Turkey, 1 - 04 November 2012, pp.1, (Full Text)
2008
200820. Baseline cytogenetic profiles of a healthy Turkish population by three test systems: Comparison between assays
Coskun E., KADIOĞLU E., Cakmak-Demircigil G., ÖZÇAĞLI E., Karahalil D. B., Burgaz S., et al.
45th Congress of the European-Societies-of-Toxicology, Rhodes, Greece, 5 - 08 October 2008, vol.180, (Summary Text)
2006
200621. Oxidative DNA damage and total antioxidant status evaluation in gram-negative sepsis rat model.
Kaymak Ç., Kadıoğlu E., ÖZÇAĞLI E., Osmanoğlu G., İzdeş S., Ağalar C., et al.
6th International Congress of Turkish Society of Toxicology, Turkey, 1 - 04 November 2006, pp.1, (Full Text)
2006
200622. Effects of using different kinds of smokeless tobacco on DNA damage; “Maras Powder”.
Çimen B., Karslı S., ÖZÇAĞLI E., Yurdun T., Şardaş S.
6th International Congress of Turkish Society of Toxicology., Turkey, 1 - 04 November 2006, pp.1
2006
200623. The role of antioxidant supplementation in occupational exposure to waste anaesthetic gases.
ÖZÇAĞLI E., Şardaş S., İzdeş S., Kanbak O., Kadıoğlu E.
8th International Symposium on Pharmaceutical Sciences (ISOPS-8), Turkey, 1 - 04 June 2006, pp.1
2005
200524. Detection of Human Papillomavirus Type 16 and 18 induced DNA damage.
ÖZÇAĞLI E., Biri A., Bozdayı G., Baltacı V., Şardaş S.
HPV and Cancer Conference, Germany, 1 - 04 October 2005, pp.1
2005
200525. Assessment of DNA damage in postmenopausal women under hormone replacement therapy.
ÖZÇAĞLI E., Şardaş S., Biri A.
42nd Congress of European Societies of Toxicology EUROTOX-2005, Poland, 1 - 04 September 2005, pp.1
2005
200526. Effects of Glutathione S-transferase (GST) polymorphisms on chromosomal aberrations and micronucleus frequencies in a Turkish population.
Aygün Kocabaş N., ÖZÇAĞLI E., Cakmak Demircigil G., Coskun E., Kadıoğlu E., Durmaz E., et al.
35th Annual Meeting of the European Environmental Mutagen Society, EEMS 2005., Greece, 1 - 04 July 2005, pp.1, (Full Text)
2005
200527. Assessment of DNA Damage in Glue Sniffers by use of the Alkaline Comet Assay.
Kadıoğlu E., ÖZÇAĞLI E., Çok İ., Şardaş S.
35th Annual Meeting of the European Environmental Mutagen Society, EEMS 2005., Greece, 1 - 04 July 2005, pp.1
2005
200528. Assessment of Genotoxic Damage by Alkaline Comet Assay in Nurses Occupationally Exposed to Anaesthetic Gases or Antineoplastic Drugs.
ÖZÇAĞLI E., Kadıoğlu E., İzdeş S., Kaymak Ç., Şardaş S.
35th Annual Meeting of the European Environmental Mutagen Society, EEMS 2005, Greece, 1 - 04 July 2005, pp.1, (Full Text)
2003
200329. Assessment of Genotoxic Damage by Alkaline Comet Assay in Nurses Occupationally Exposed to Anaesthetic Gases or Antineoplastic Drugs.
İzdeş S., Şardaş S., Alhayıroğlu E., Kaymak Ç., CİVELEK E.
5th International Congress of Turkish Society of Toxicology., Turkey, 1 - 04 November 2003, pp.1
2003
200330. Chromosomal Aberrations Under Basal Conditions and After Treatment with X-ray in Human Lymphocytes as Related to the GSTM1Genotype.
CİVELEK E., Şardaş S., Aygün Kocabaş N., Karahalil B., Alhayıroğlu E., Karakaya A. E.
5th International Congress of Turkish Society of Toxicology., Turkey, 1 - 04 November 2003, pp.1, (Full Text)
2003
200331. Assessment of DNA damage in women using oral contraceptives.
CİVELEK E., Şardaş S., Karahalil B., Biri A.
5th International Congress of Turkish Society of Toxicology, Turkey, 1 - 04 November 2003, pp.1
2003
200332. Assessment of DNA Damage in Nurses Occupationally Exposed to Anesthetic Gases And Protective Role of Antioxidant Supplementation.
Alhayıroğlu E., CİVELEK E., İzdeş S., Şardaş S.
7th International Symphosium on Pharmaceutical Sciences., Turkey, 1 - 04 June 2003, pp.1
2001
200133. The Evaluation of Relation to GSTM1 Genetic Polymorphism and Chromosomal Aberrations and Challenge Assay.
Karahalil B., Aygün Kocabaş N., CİVELEK E., Karakaya A. E., Şardaş S.
EUROTOX-2001,, Turkey, 1 - 04 September 2001, pp.1
2001
200134. Assessment of Genotoxic Damage in Lead Exposed Baterry Manufacturers by Challenge Assay.
CİVELEK E., Karakaya A. E., Ertaş N., Ilgıt E., Şardaş S.
EUROTOX-2001, Turkey, 1 - 04 September 2001, pp.1, (Full Text)
2000
200035. Determination of Genotoxic Damage by Alkaline Comet Assay in Glue Sniffers.
Çok İ., CİVELEK E., Arıkan G., Şardaş S.
EUROTOX-2000,, United Kingdom, 1 - 04 September 2000, pp.1, (Full Text)
2000
200036. Assessment of DNA Repair Capacity of Operating Room Personnel Exposed to Anaesthetic Gases by Comet Assay. Biomarkers of genetic and acquired susceptibility
CİVELEK E., Şardaş S., Cuhruk H., Karakaya A. E.
Center for Environmental Research and Technology-Epidemiology Dept Workshop on Challenge Assay, Germany, 1 - 04 September 2000, pp.1-2, (Full Text)
2000
200037. The Use of Challenge Assay in Determining DNA Repair Capacity of Operating Room Personnel Exposed to Anaesthetic Gases by Single Cell Gel Electrophoresis Technique
CİVELEK E., Şardaş S., Cuhruk H., Karakaya A. E.
6th International Symposium on Pharmaceutical Sciences ISOPS-6, Turkey, 1 - 04 June 2000, pp.1-2
2000
200038. Assessment of Possible DNA Damage in Glue Sniffers by Single Cell Gel Electrophoresis Technique.
Çok İ., CİVELEK E., Arıkan G., Şardaş S.
. 6th International Symposium on Pharmaceutical Sciences ISOPS-6, Turkey, 1 - 04 June 2000, pp.1-2
Books
2025
20251. Therapeutic Targeting of Telomerase.
Özçağlı E., Yesilcimen Soylemez E., Sevim Ç., Kara M., Tsatsakis A.
in: Telomeres, Aristidis Tsatsakis, Editor, Jenny Stanford Publ Pte Ltd, New York, pp.669-697, 2025
2021
20212. Chapter12: Health-based exposure limits and toxicology in the pharmaceutical industry
Özçağlı E., Tsatsakis A. M.
in: Toxicological Risk Assessment and Multi-System Health Impacts From Exposure, Aristidis M. Tsatsakis, Editor, Academic Press , London, pp.131-137, 2021
2020
20203. Chapter 40. Turkey
Coşkun E., Özçağlı E.
in: Information Resources in Toxicology 5th Edition, Philip Wexler, Editor, Academic Press , London, pp.557-565, 2020
2018
20184.
Özçağlı E.
in: , Mehmet Salih Gürel,Zeynep Solakoğlu, Editor, İstanbul Medikal Yayıncılık, İstanbul, pp.227-228, 2018
2017
20175. Food Toxicology
Özçağlı E.
in: Cassarett&Doull’s Essentials of Toxicology,, Sinan Süzen,Pınar Erkekoğlu,Ahmet Oğuz Ada,Onur Erdem,Gonca Çakmak Demircigil,Bulut,Demirel, Editor, Nobel Yayın Dağıtım, Ankara, pp.453-461, 2017
2014
20146. An Update on the Signifi cance of Pharmacovigilance in Patient Safety.
ÖZÇAĞLI E., Dionysios V., Alpertunga B., Tsatsakis A.
in: Toxicological problems, Dishovsky C., Radenkova-Saeva J., Editor, Military Publishing House, Sofia, pp.263-267, 2014
Funded Projects
2017 - 2019
2017 - 2019Klopidogrel Kullanımı Sonrasında Gözlenen İnme Olaylarında CYP2C19 Gen Polimorfizminin Etkisi ve Maliyet Sonuç Analizi
Project Supported by Higher Education Institutions , BAP MSc
ÖZÇAĞLI E. (Executive), AKSAN E.
2018 - 2018
2018 - 2018Toksik maddelerin etkilerinin in vitro kuşullarda araştırılması
Project Supported by Higher Education Institutions , BAP Other
KARA M. (Executive), ÖZÇAĞLI E., ALPERTUNGA B., KOTİL T.
2016 - 2018
2016 - 2018FUMONİSİN B1 VE AFLATOKSİN B1İN NÖRODEJENERATİF MEKANİZMALAR ÜZERİNE ETKİSİNİN İN-VİTRO KOŞULLARDA ARAŞTIRILMASI
Project Supported by Higher Education Institutions , BAP Other
KARA M. (Executive), JANNUZZI A. T., ÖZÇAĞLI E.
2017 - 2017
2017 - 2017Assessing the role of celastrole on cisplatin induced nephrotoxicity under in vitro conditions
Project Supported by Higher Education Institutions , BAP Other
ALPERTUNGA B. (Executive), ÖZÇAĞLI E., JANNUZZI A. T., BORAN T., GÜNAYDIN A.
2017 - 2017
2017 - 2017Risk assessment for children exposed to DDT residues in various milk types from the Greek market
Project Supported by Higher Education Institutions , BAP Other
ÖZÇAĞLI E. (Executive)
2017 - 2017
2017 - 2017Immunohistochemistry analysis and TERT PTEN protein expressions in Stanozolol exposure
Project Supported by Higher Education Institutions , BAP Other
ÖZÇAĞLI E. (Executive), KARA M., KOTİL T., ALPERTUNGA B.
2016 - 2017
2016 - 2017Stanozolole Maruziyetin Sıçan Lenfositleri Üzerinde DNA Hasarı Oluşturma Potansiyeli Açısından Araştırılması
Project Supported by Higher Education Institutions , BAP Other
ÖZÇAĞLI E. (Executive), ALPERTUNGA B., KARA M.
2015 - 2016
2015 - 2016Pharmacovigilance Activities in Children
Project Supported by Higher Education Institutions , BAP Other
ÖZÇAĞLI E. (Executive)
2013 - 2015
2013 - 20153-monokloropropan-1,2-diol (3-MCPD)?ün ve metabolitlerinin genotoksisitesinin ve DNA onarımı üzerine etkisinin NRK-52E hücreleri üzerinde araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
ÖZÇAĞLI E. (Executive)
2014 - 2014
2014 - 2014Evaluation of DNA damage in NRK 52E cells following in vitro treatment of 3-MCPD and its metabolites
Project Supported by Higher Education Institutions , BAP Other
ÖZÇAĞLI E. (Executive)
2003 - 2006
2003 - 2006İnsan periferal kanında genotoksik etki ile GSH düzeyi arasındaki ilişkinin belirlenmesi
Project Supported by Higher Education Institutions , BAP Research Project
Şardaş S.(Executive), Özçağlı E., Kadıoğlu E., Nakiboğlu H.
2003 - 2005
2003 - 2005
“Türk Popülasyonunda Gen Polimorfizmi ile Kanser Riski Arasındaki İlişkinin Sitogenetik ve Moleküler Biyoizlenimi”, Devlet Planlama Teşkilatı
CB Strateji ve Bütçe Başkanlığı (Kalkınma Bakanlığı) Projesi
ÖZÇAĞLI E.
Activities in Scientific Journals
2019 - Present
2019 - PresentToxicology Reports
Assistant Editor/Section Editor
2013 - 2017
2013 - 2017Committee Member
Peer Reviews in Scientific Publications
September 2015
September 2015Food And Chemical Toxicology
SCI Journal
February 2015
February 2015Food And Chemical Toxicology
SCI Journal
February 2015
February 2015İstanbul Üniversitesi Eczacılık Fakültesi Dergisi
National Scientific Refreed Journal
February 2015
February 2015Food And Chemical Toxicology
SCI Journal
February 2015
February 2015Food And Chemical Toxicology
SCI Journal
December 2014
December 2014Food And Chemical Toxicology
SCI Journal
December 2014
December 2014Food and Chemical Toxicology
SCI Journal
March 2014
March 2014Food and Chemical Toxicology
SCI Journal
February 2014
February 2014Food and Chemical Toxicology
SCI Journal
Scientific Project Refereeing
July 2015
July 2015Congress and Symposium Activities
30 October 2018 - 31 October 2018
30 October 2018 - 31 October 2018World HPAPI Congress
Invited Speaker
Basel-Switzerland
13 October 2017 - 17 October 2017
13 October 2017 - 17 October 20174. Ulusal Eczacılık Kongresi, ECKON
Invited Speaker
İstanbul-Turkey
21 December 2016 - 24 December 2016
21 December 2016 - 24 December 201613. Türkiye Eczacılık Kongresi
Invited Speaker
İstanbul-Turkey
13 September 2015 - 16 September 2015
13 September 2015 - 16 September 201551st Congress of European Societies of Toxicology EUROTOX 2015 Congress
Session Moderator
Porto-Portugal
13 September 2015 - 16 September 2015
13 September 2015 - 16 September 201551st Congress of European Societies of Toxicology EUROTOX 2015 Congress
Invited Speaker
Porto-Portugal
08 June 2015 - 08 June 2015
08 June 2015 - 08 June 2015ISPE
Invited Speaker
İstanbul-Turkey
01 January 2012 - 01 January 2012
01 January 2012 - 01 January 2012Farmakovijilans Toplantısı , “Vijilansa Stratejik Bakış: Tehditler ve Fırsatlar”
Attendee
İstanbul -Turkey
30 May 2009 - 01 June 2009
30 May 2009 - 01 June 2009