Prof. Dr. Pınar AKSOY SAĞIRLI

Yayın Ağı

Makaleler 24

1. Up to date: Endoplasmic reticulum stress-targeted colorectal cancer therap

Arcan G. G., Aksoy Sağırlı P.

İstanbul Journal of Pharmacy , cilt.55, sa.1, ss.119-130, 2025 (Hakemli Dergi)

2. Biological activities of Helleborus vesicarius: Cytotoxicity, induction of apoptosis and antioxidant potential

ALTIPARMAK ÜLBEGİ G., Ozsoy N., KÜLTÜR Ş., MELİKOĞLU G., AKSOY SAĞIRLI P.

Journal of Research in Pharmacy , cilt.29, sa.3, ss.1134-1144, 2025 (ESCI)

3. A new lectin from Amanita vaginata mushroom with potent anti-inflammatory activity

Seliman T. M. H., Ozsoy N., Altıparmak Ülbegi G., Alp-Kavlo H., Arcan G. G., Akev N., et al.

Natural Product Research , 2025 (SCI-Expanded)

4. Therapeutic Effects of Aqueous Infusion of Cotinus coggygria Scop Leaves on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice

ÖZTÜRK SEYHAN N., Ozgur S., Ozal-Coskun C., Arda P., Ozsoy N., AKSOY SAĞIRLI P., et al.

Chinese Journal of Integrative Medicine , 2025 (SCI-Expanded)

5. **Sesquiterpene Coumarins, Chromones, and Acetophenone Derivatives with Selective Cytotoxicities from the Roots of Ferula caspica M. Bieb. (Apiaceae)**

Kuran F. K., Altıparmak Ülbegi G., Arcan G. G., Eruçar F. M., Karavuş Ş. N., Aksoy Sağırlı P., et al.

PHARMACEUTICALS , cilt.17, sa.10, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

6. **Anti-inflammatory activity of a novel lectin isolated from Pleurotus eryngii var. ferulae mushroom**

Seliman T., Altiparmak Ülbegi G., Özsoy N., Kavlo H., Aksoy Sağırlı P.

ISTANBUL JOURNAL OF PHARMACY , sa.2, ss.195-204, 2024 (ESCI) Sürdürülebilir Kalkınma

7. Sesquiterpene Coumarin Ethers with Selective Cytotoxic Activities from the Roots of Ferula huber-morathii Pesmen (Apiaceae) and Unequivocal Determination of the Absolute Stereochemistry of Samarcandin

ERUÇAR F. M., KURAN F. K., Ulbegi G. A., ÖZBEY S., KARAVUŞ Ş. N., ARCAN G. G., et al.

PHARMACEUTICALS , cilt.16, sa.6, 2023 (SCI-Expanded, Scopus)

8. Novel Cytotoxic Sesquiterpene Ester Derivatives from the Roots of Ferula mervynii

Yazıcı Bektaş N., Altıparmak Ülbegi G., Aksoy Sağırlı P., Miski M.

Chemistry and Biodiversity , cilt.20, sa.3, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

9. Identification of AKT1/beta-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment

HASBAL ÇELİKOK G., Aksoy-Sagirli P., Altiparmak-Ulbegi G., Can A.

ONCOLOGY LETTERS , cilt.21, sa.3, 2021 (SCI-Expanded, Scopus)

10. Phenolic profile, antioxidant, antidiabetic, DNA protection, and cytotoxic activities of Allium kurtzianum

YILMAZ ÖZDEN T., HASBAL ÇELİKOK G., Aksoy-Sagirli P., Altiparmak-Ulbegi G., Kocyigit M., CAN A. A., et al.

INTERNATIONAL FOOD RESEARCH JOURNAL , cilt.27, sa.6, ss.1001-1009, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

11. Antioxidant, Anti-acetylcholinesterase, Anti-inflammatory and DNA Protection Activities of Glaucium grandiflorum var. grandiflorum

Ozsoy N., Yilmaz-Ozden T., Aksoy-Sagirli P., Şahin H., Sari A.

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH , cilt.17, ss.677-684, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

12. Association of Three Single Nucleotide Polymorphisms in MTR and MTRR Genes with Lung Cancer in a Turkish Population

Aksoy-Sagirli P., Erdenay A., Kaytan-Saglam E., Kizir A.

GENETIC TESTING AND MOLECULAR BIOMARKERS , cilt.21, ss.428-432, 2017 (SCI-Expanded) Sürdürülebilir Kalkınma

13. In vitro biological effects of Crataegus microphylla C. Koch

Aksoy-Sagirli P., Yilmaz-Ozden T., Ozsoy N., Çelik B., Kultur S., Melikoglu G.

INDIAN JOURNAL OF TRADITIONAL KNOWLEDGE , cilt.16, sa.2, ss.189-196, 2017 (SCI-Expanded)

14. In vitro antioxidant activity, cyclooxygenase-2, thioredoxin reductase inhibition and DNA protection properties of Teucrium sandrasicum L.

Aksoy-Sagirli P., Ozsoy N., Ecevit-Genc G., Melikoglu G.

Industrial Crops and Products , cilt.74, ss.545-550, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

15. HMG-CoA Reductase Inhibitors Decrease Hyperglycemia on Animal Model of Systemic Inflammatory Response Syndrome (SIRS)

AKSOY P., Brown M. J., Chini E. N.

J Anesthe Clinic Res , cilt.2, sa.9, 2011 (Hakemli Dergi)

16. Paraoxonase-1 192/55 Polymorphisms and the Risk of Lung Cancer in a Turkish Population

Aksoy-Sagirli P., Cakmakoglu B., Isbir T., Kaytan-Saglam E., Kizir A., Topuz E., et al.

ANTICANCER RESEARCH , cilt.31, sa.6, ss.2225-2229, 2011 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. Natriuretic peptide pharmacogenetics: Membrane metallo-endopeptidase (MME): Common gene sequence variation, functional characterization and degradation

Pereira N. L., Aksoy P., Moon I., Peng Y., Redfield M. M., Burnett J. C., et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY , cilt.49, sa.5, ss.864-874, 2010 (SCI-Expanded)

18. Natriuretic Peptide Pharmacogenomics: Common Gene Sequence Variation and Functional Characterization of Membrane Metallo-Endopeptidase (MME)

Pereira N. L., Aksoy P., Moon I., Redfield M., Burnett J., Weinshilboum R.

FASEB JOURNAL , cilt.24, 2010 (SCI-Expanded)

19. Cytosolic 5 '-nucleotidase III (NT5C3): gene sequence variation and functional genomics

Aksoy P., Zhu M. J., Kalari K. R., Moon I., Pelleymounter L. L., Eckloff B. W., et al.

PHARMACOGENETICS AND GENOMICS , cilt.19, sa.8, ss.567-576, 2009 (SCI-Expanded)

20. Apurinic/Apyrimidinic Endonuclease (APE1) Gene Polymorphisms and Lung Cancer Risk in Relation To Tobacco Smoking

Ağaçhan B., Kucukhuseyin O., Aksoy P., Turna A., Yaylim I., Görmüş U., et al.

ANTICANCER RESEARCH , cilt.29, sa.6, ss.2417-2420, 2009 (SCI-Expanded) Sürdürülebilir Kalkınma

21. Gemcitabine pharmacogenomics: Deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics

Kocabas N. A., Aksoy P., Pelleymounter L. L., Moon I., Ryu J., Gilbert J. A., et al.

DRUG METABOLISM AND DISPOSITION , cilt.36, sa.9, ss.1951-1959, 2008 (SCI-Expanded)

22. The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity

Barbosa M. T. P., Soares S. M., Novak C. M., Sinclair D., Levine J. A., AKSOY P., et al.

FASEB JOURNAL , cilt.21, sa.13, ss.3629-3639, 2007 (SCI-Expanded) Sürdürülebilir Kalkınma

23. Regulation of SIRT 1 mediated NAD dependent deacetylation: A novel role for the multifunctional enzyme CD38

AKSOY P., Escande C., White T. A., Thompson M., Soares S., Benech J. C., et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , cilt.349, sa.1, ss.353-359, 2006 (SCI-Expanded)

24. Regulation of intracellular levels of NAD: A novel role for CD38

AKSOY P., White T. A., Thompson M., Chini E. N.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , cilt.345, sa.4, ss.1386-1392, 2006 (SCI-Expanded)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 27

1. Role of the AKT1 and CTNNB1 mutations in paclitaxel resistance

Altıparmak Ülbegi G., Hasbal Çelikok G., Aksoy Sağırlı P.

The 49th FEBS Congress, İstanbul, Türkiye, 5 - 09 Temmuz 2025, ss.286, (Özet Bildiri)

2. Effects of Pro-Resolving Lipid Mediators on Nitric Oxide and Prostacyclin Pathways in Human Endothelial Cells

Aslan M. S., Çelik Z., Altıparmak Ülbegi G., Aksoy Sağırlı P., Topal Tanyılmaz G.

4th AtheroNET Meeting, Sarajevo, Bosna-Hersek, 14 - 16 Mayıs 2025, ss.58-60, (Özet Bildiri)

3. COMPARING THE CHEMICAL COMPOSITION AND CYTOTOXIC ACTIVITY PROFILES OF NEW FERULA PLANTS FROM MERWIA SECTION GROWING NATIVE IN TÜRKİYE'

Eruçar F. M., Altıparmak Ülbegi G., Senadeera S. P., Aksoy Sağırlı P., Beutler J. A., Miski M.

The 10th International Mediterranean Symposium on Medicinal and Aromatic Plants, İstanbul, Türkiye, 25 - 27 Nisan 2024, ss.68, (Özet Bildiri)

4. Cytotoxic Daucane Esters from the Dichloromethane Extract of the Roots of Endemic Ferula pisidica Akalın & Miski (Apiaceae)

Karavuş Ş. N., Arcan G. G., Aksoy Sağırlı P., Miski M.

ASP 2023 Annual Meeting, Maryland, Amerika Birleşik Devletleri, 22 - 26 Temmuz 2023, ss.54, (Özet Bildiri) Sürdürülebilir Kalkınma

5. Cyp1a1, Cyp2e1 Gene Polymorphisms, Smoking And Lung Cancer In Turkish Population.

AKSOY SAĞIRLI P., Kizir A., Topuz E., Özden İ., Berkkan H.

1st Congress of Molecular Medicine, İstanbul, Türkiye, ss.413, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

6. Investigation of MTHFR C677T gene polymorphism in patient with lung cancer.

Kurulgan E., Ergen A., Yılmaz H., AKSOY SAĞIRLI P., isbir T.

Third International congress of Molecular Medicine, İstanbul, Türkiye, ss.342, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

7. Identification of AKT1/CTNNB1 mutations conferring cetuximab and chemotherapeutic drugs resistance in colorectal cancer treatment

Hasbal G., Aksoy Sağırlı P., Can A.

2nd Eurosia Biochemical Approaches and Technologies Congress, Antalya, Türkiye, 26 - 29 Ekim 2019, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

8. The cytotoxic effects of Ornithogalum oligophyllum and Ornithogalum umbellatum extracts

Altıparmak Ülbegi G., Hasbal G., Aksoy Sağırlı P., Yılmaz Özden T., Koçyiğit Avcı M., Yanardağ R., et al.

2nd Eurasian Biochemical Approaches & Technologies (EBAT) Congress, Antalya, Türkiye, 26 - 29 Ekim 2019, ss.157, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

9. Antidiabetic, acetylcholinesterase inhibitor and cytotoxic activities of the root extracts of Ferula mervynii

YAZICI BEKTAŞ N., YILMAZ ÖZDEN T., AKSOY SAĞIRLI P., ALTIPARMAK ÜLBEGİ G., MİSKİ M.

Phytopharm 2019, St. Petersburg, Rusya, 1 - 03 Temmuz 2019, cilt.17, ss.78-79, (Özet Bildiri)

10. Antioxidant activities of Ornithogalum umbellatum

Yılmaz Özden T., Hasbal G., Koçyiğit Avcı M., Yanardağ R., Aksoy Sağırlı P., Altıparmak Ülbegi G., et al.

II. Eurasian Agriculture and Natural Sciences Congress, Baku, Azerbaycan, 11 - 15 Eylül 2018, ss.130, (Tam Metin Bildiri)

11. Antioxidant and in vitro enzyme inhibitory effects of Ornithogalum oligophyllum

Yılmaz Özden T., Hasbal G., Koçyiğit Avcı M., Yanardağ R., Aksoy Sağırlı P., Altıparmak Ülbegi G., et al.

2nd International Congress on Advances in Bioscience and Biotechnology (ICABB), Podgorica, Karadağ, 26 - 30 Haziran 2018, ss.41, (Tam Metin Bildiri)

12. Identification of the association between BHMT, CHDH and PEMT polymorphisms and rectal cancer in a Turkish population

Altıparmak Ülbegi G., Erdenay A., Kaytan Sağlam E., Yaylım İ., Aksoy Sağırlı P.

2nd International Congress on Advances in Bioscience and Biotechnology (ICABB), Podgorica, Karadağ, 26 - 30 Haziran 2018, ss.45, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

13. In vitro antioxidant, DNA protection capacities and cytotoxic activities of Allium kurtzianum extracts

Hasbal G., Yılmaz Özden T., Aksoy Sağırlı P., Altıparmak İlbegi G., Koçyiğit Avcı M., Can A., et al.

The 21th International Congress Phytopharm 2017 and 10th Anniversary of the TCM Research Center Graz, Graz, Avusturya, 2 - 05 Temmuz 2017, cilt.15, ss.71, (Tam Metin Bildiri)

14. Helleborus vesicarius Aucher Bitkisinin Antioksidan ve Antikanser Aktiviteleri

AKSOY SAĞIRLI P., ÖZSOY N., ANIL S., KÜLTÜR Ş., MELİKOĞLU G.

22. Bİtkisel İlaç Hammaddeleri Toplantısı, Trabzon, Türkiye, 31 Ağustos - 05 Eylül 2016, ss.142, (Tam Metin Bildiri)

15. Investigating into the mechanism of action of Xanthium strumarium extracts for its anticancer effects against different leukemic cell lines

BEYATLI A., Süleymanoğlu M., Çelik D. D., AKSOY SAĞIRLI P., VAROL B., KURUCA D. S.

9th CMAPSEEC, 26 - 29 Mayıs 2016, (Özet Bildiri)

16. Association of Polymorphisms in One Carbon Metabolism Genes with Lung Cancer in a Turkish Population

Erdenay A. E., Altıparmak G., Kaytan-Sağlam E., Kizir A., AKSOY SAĞIRLI P.

International Symposium on Advances in Predictive & Personalized Medicine, İstanbul, Türkiye, 2 - 03 Nisan 2015, ss.14, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

17. Investigation of association between paraoxonase-1 192/55 polymorphisms and serum paraoxonase activity in lung cancer

Aksoy P., Agachan B., İSBİR T., Kizir A., Topuz E., Berkkan H.

9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Türkiye, 4 - 08 Eylül 2010, cilt.42, ss.263, (Özet Bildiri) Sürdürülebilir Kalkınma

18. Degredation mechanisms responsible for decreased levels of a neutral endopeptidase (NEP) variant allozyme.

AKSOY SAĞIRLI P., Pereira N., Weinshilboum R.

49th American Society of Cell Biology Meeting,, San Diego, Amerika Birleşik Devletleri, 4 - 09 Aralık 2009, ss.1, (Tam Metin Bildiri)

19. Assocıatıon Of Apurınıc/Apyrımıdınıc Endonuclease (Ape1) Gene Polymorphısms Wıth Lung Cancer In Males.

AĞAÇHAN B., Küçükhüseyin Ö., Aksoy Sağırlı P., Yaylım Eraltan İ., Turna A., Görmüş U., et al.

III. International Congress of Molecular Medicine, İstanbul, Türkiye, 5 - 08 Mayıs 2009, cilt.61, sa.3, ss.330, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

20. Cytosolic, 5’-nucleotidase III (NT5C3) gene sequence variations and functional genomics

AKSOY SAĞIRLI P., Zhu M., Kalari K., Moon İ., pelleymounter L., Eckloff B., et al.

American Society of Clinical Pharmacology and Therapeutics Annual Meeting,, Washington, Amerika Birleşik Devletleri, 19 - 22 Mart 2009, ss.47, (Tam Metin Bildiri)

21. CYTOSOLIC 5 '-NUCLEOTIDASE III (NT5C3) GENE SEQUENCE VARIATION AND FUNCTIONAL GENOMICS: CYTOSINE ARABINOSIDE AND GEMCITABINE PHARMACOGENETICS

Aksoy P., Zhu M., Kalari K. R., Moon I., Pelleymounter L. L., Eckloff B. W., et al.

110th Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Maryland, Amerika Birleşik Devletleri, 18 - 21 Mart 2009, cilt.85

22. Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

AKSOY SAĞIRLI P., Aygün Kocabaş N., Gilbert J., Salavaggione O. E., Eckloff B., Wieben E., et al.

American Society of Clinical Pharmacology and Therapeutics Annual Meeting, Orlando, Amerika Birleşik Devletleri, 2 - 05 Nisan 2008, ss.18, (Tam Metin Bildiri)

23. Gemcitabine pharmacogenomics: Deoxycytidine kinase (DCK) and cytidine monophosphate kinase (CMPK) gene sequence variation and functional genomics.

Aksoy P., Kocabas N. A., Pelleymounter L. L., Gilbert J. A., Salavaggione O. E., Eckloff B. W., et al.

109th Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Florida, Amerika Birleşik Devletleri, 2 - 05 Nisan 2008, cilt.83, (Özet Bildiri)

Kitaplar 6

Metrikler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

840

H-İndeks (WoS)

Atıf (Scopus)

864

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler