Lect. PhD ZELİHA EMRENCE


Aziz Sancar Institute of Experimental Medicine, Department of Genetics


WoS Research Areas: Life Sciences (Life), Molecular Biology & Genetics, Biology, Cell Biology


Scopus Research Areas: Molecular Biology, Cell Biology


Avesis Research Areas: Life Sciences, Molecular Biology and Genetics, Genetic Disorders, Moleculer Biology of Cancer, Natural Sciences

Email: zeliha.emrence@istanbul.edu.tr
Office Phone: +90 212 414 2000 Extension: 33316
Web: http://aves.istanbul.edu.tr/41878/
Office: İ.Ü.Aziz Sancar Deneysel Tıp Araştırma Enstitüsü, Genetik AD Kat:2

Metrics

Publication

76

Publication (WoS)

30

Publication (Scopus)

27

Citation (WoS)

1205

H-Index (WoS)

11

Citation (Scopus)

1320

H-Index (Scopus)

11

Citation (Scholar)

51

H-Index (Scholar)

1

Citation (Sobiad)

3

H-Index (Sobiad)

1

Project

21

Open Access

2
UN Sustainable Development Goals

Education

2010 - 2016

2010 - 2016

Doctorate

Istanbul University, Health Sciences Institute, Genetik, Turkey

2008 - 2010

2008 - 2010

Postgraduate

Istanbul University, Health Sciences Institute, Genetik, Turkey

2006 - 2008

2006 - 2008

Undergraduate

Marmara University, Fen Edebiyat Fakültesi, Biyoloji, Turkey

2004 - 2006

2004 - 2006

Undergraduate

Trakya University, Fen Fakültesi, Biyoloji, Turkey

Dissertations

2016

2016

Doctorate

Nükleolar Protein 7 Geninin All-Trans Retinoik Asit Tedavisindeki Rolü

Istanbul University, Aziz Sancar Institute of Experimental Medicine, Genetik

2010

2010

Postgraduate

Ailevi akdeniz ateşi hastalığından sorumlu olduğu düşünülen MEFV geninin 3'UTR bölgesindeki varyasyonların araştırılması

Istanbul University, Deneysel Tıp Araştırma Enstitüsü, Genetik

Foreign Languages

B2 Upper Intermediate

B2 Upper Intermediate

English

Research Areas

Life Sciences

Molecular Biology and Genetics

Genetic Disorders

Moleculer Biology of Cancer

Natural Sciences

Research Areas Based on Academic Activities

Avesis Research Areas

    WoS Research Areas

      Scopus Research Areas

        Academic Positions

        2020 - Present

        2020 - Present

        Lecturer PhD

        Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics

        2012 - 2020

        2012 - 2020

        Research Assistant PhD

        Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics

        Articles

        All (34)
        SCI-E, SSCI, AHCI (25)
        SCI-E, SSCI, AHCI, ESCI (26)
        ESCI (1)
        Scopus (27)
        TRDizin (3)
        Other Publications (6)

        Papers Presented at Peer-Reviewed Scientific Conferences

        2024

        2024

        3. Cytokine Signature Differences in Major Phenotypic Groups of Behçet’s Disease

        DENİZ R., EMRENCE Z., Punar S., İleri B., ARĞA K. Y., ALİBAZ ÖNER F., et al.

        20th International Conference on Behçet’s Disease, Morocco, 18 September 2024, (Summary Text)

        2023

        2023

        4. Reductase 2 (DHRS2) can be the novel inflammatory response regulator in breast cancer cells

        Salman Yaylaz B., SIRMA EKMEKCİ S., punar ş., ileri b., EMRENCE Z., ABACI N.

        18. uluslararası katılımlı tıbbi biyoloji ve genetik kongresi, İstanbul, Turkey, 26 October 2023, vol.2, pp.31, (Summary Text)

        2023

        2023

        5. Akut T-Hücreli Lösemide Transkripsiyon Faktörü LEF1’in INSL5 ile İlişkisi

        EMRENCE Z.

        18. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Turkey, 26 - 29 October 2023, vol.2, pp.7, (Summary Text)

        2023

        2023

        6. The Relationship Between the NETosis Findings and Disease Activity in Behcet Disease

        Bektaş E., Deniz R., Emrence Z., Sırma Ekmekci S., Abacı N., Amikishiyev S., et al.

        ACR 2023, California, United States Of America, 10 - 15 November 2023, pp.4988-5002, (Summary Text) Creative Commons License

        2023

        2023

        7. Akut T-Hücreli Lösemide Transkripsiyon Faktörü LEF1’in INSL5 ile İlişkisi

        Emrence Z.

        18. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Turkey, 26 - 29 October 2023, pp.19, (Summary Text) Creative Commons License Sustainable Development

        2023

        2023

        9. DHRS2'nin Meme Kanseri Hücrelerinde İnflamatuar Yanıta Olan Etkisi

        Salman Yaylaz B., Sırma Ekmekci S., Punar Ş., İleri B., Emrence Z., Abacı N.

        18. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Turkey, 26 - 29 October 2023, pp.44, (Summary Text) Creative Commons License Sustainable Development

        2021

        2021

        11. SPINK2 Gene Expression In Acute Myeloid Leukemia

        Gezer S., Emrence Z., Sarıman M., Paçal F., Abacı N., Sırma Ekmekci S.

        8th International Medicine and Health Sciences Researches Congress, Ankara, Turkey, 25 - 26 December 2021, vol.1, pp.215-220, (Full Text)

        2021

        2021

        12. Effect of the transcription factor CEBPB on MN1 expression

        Emrence Z., Sarıman M., Salman Yaylaz B., Abacı N., Sırma Ekmekci S.

        XVII. Tıbbi Biyoloji ve Genetik Kongresi 28-31 Ekim 2021 Online, İstanbul, Turkey, 28 - 31 October 2021, vol.52, no.1, pp.45-46, (Summary Text) Creative Commons License

        2021

        2021

        13. Investigation of Electroporation Technique’s Effects on Acute Leukemia Cell Lines

        Salman Yaylaz B., Punar Ş., Emrence Z., Sırma Ekmekci S., Şakar D. N., İleri B., et al.

        XVII. Tıbbi Biyoloji ve Genetik Kongresi, İstanbul, Turkey, 28 - 31 October 2021, vol.52, no.1, pp.318-319, (Summary Text) Creative Commons License

        2019

        2019

        15. Effect of Doxorubicin on Expression of RNA m6A Methylation Enzymes in Leukemia Cell Lines

        EMRENCE Z., Sariman M., Salman B., ABACI N., SIRMA EKMEKCİ S.

        1.International Multidisciplinary Cancer Research Congres, Diyarbakır, Turkey, 19 - 22 September 2019, pp.127, (Full Text)

        2018

        2018

        16. Does HMGB1 gene silence really attenuate doxorubicin’s cardiotoxicity

        TAŞKIN GÜVEN E., GÜVEN C., Sarıman M., EMRENCE Z., SIRMA EKMEKCİ S., ABACI N., et al.

        7th World Congress of Oxidative Stress, Calcium Signaling and TRP Channels, Isparta, Turkey, 20 April 2018, pp.704, (Summary Text)

        2017

        2017

        19. HLA-B*51 ekspresyonundaki artış endoplazmik retikulum stresi ile ilişkili olabilir

        Coşan F., Emrence Z., Azaklı H., Sırma Ekmekci S., Abacı N., Çetin E., et al.

        18.Ulusal Romatoloji Kongresi, Antalya, Turkey, 18 - 22 October 2017, vol.9, pp.12-13, (Summary Text)

        2017

        2017

        24. ‘The role of NOL7 Gene in All Trans Retinoid Acid Resistance of Acute Myeloid Leukemia Cells’.

        EMRENCE Z., sarıman m., ÇINAR S., salman b., biberoğlu n. e., ABACI N., et al.

        European Human Genetic Conference 2017, Copenhangen, Denmark, 27 - 30 May 2017, (Summary Text)

        2016

        2016

        27. Inhibition of AMPK by Doxorubicin Exacerbates Cardiomyocytes Death Role of TLR4

        GÜVEN C., TAŞKIN GÜVEN E., sarıman m., EMRENCE Z., ABACI N., SIRMA EKMEKCİ S., et al.

        42.National Physiology congress, Turkey, 5 - 08 September 2016, vol.218, pp.26-91, (Summary Text)

        2014

        2014

        30. A15924G mt-tRNAT Gene Mutation is not the Primary Cause of Mitochondrial Myopathies

        ÇAKİRİS A., ABACI N., EMRENCE Z., PAÇAL F., GÜRSES R. C., Kara B., et al.

        64th American Society of Human Genetics Annual Meeting in San Diego, California, United States Of America, 18 - 22 October 2014, pp.68, (Full Text)

        2013

        2013

        32. LEF1 controls expression of HEP27, which is a posttanslational regulator of p53

        Ekmekci S. S., ABACI N., Gulec C., EMRENCE Z., Ekmekci C. G., ÜSTEK D.

        XIII.National congress of medical biology and genetics, Aydın, Turkey, 27 - 31 October 2013, pp.360-361, (Summary Text)

        2012

        2012

        33. Genome-Wide Analysis Reveals a Recessive Association of ERAP1 Variants with Behcet's Disease and Epistasis Between ERAP1 and HLA-B*51.

        REMMERS E. F., KIRINO Y., BERTSIAS G., ISHIGATSUBO Y., KIM Y., OMBRELLO M. J., et al.

        Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, Kiribati, 9 - 14 November 2012, vol.64, (Summary Text) identifier

        2012

        2012

        34. Targeted Deep Re-Sequencing Implicates Rare and Low Frequency Coding Variants in IL23R, MEFV, TLR4, and NOD2 in Behcet's Disease

        KIRINO Y., ZHOU Q., ISHIGATSUBO Y., MIZUKI N., TUGAL-TUTKUN I., Seyahi E., et al.

        Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, Kiribati, 9 - 14 November 2012, vol.64, (Summary Text) identifier

        2012

        2012

        35. Decreased IL-17(+) CD16(+) and IL-10(+) CD16(+) NK cells in Behcet's disease

        Cosan F., Cetin E. A., Akdeniz N., Emrence Z., Cefle A., Deniz G.

        European Congress of Immunology, Glasgow, England, 5 - 08 September 2012, vol.137, pp.221-222, (Summary Text) identifier

        2012

        2012

        38. XBP1 SPLICING AND REDUCED XBP1 EXPRESSION IN BEHCET'S DISEASE

        Cosan F., Cetin e., akdeniz N., EMRENCE Z., gecgel f., erbağ g., et al.

        eular 2012, Berlin, Germany, 6 - 09 June 2012, pp.2, (Summary Text)

        2011

        2011

        40. An Insertion Mutation in the MDFIC (MyoD Family Inhibitor Domain Containing) Gene Defines a Novel Autoinflammatory Syndrome Associated with Lymphedema

        Gül A., Ustek D., Hatemi G., Azakli H., Emrence Z., Cosan F., et al.

        75th Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) / 46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals (ARHP), Illinois, United States Of America, 4 - 09 November 2011, vol.63, (Summary Text) identifier

        2010

        2010

        41. MEFV Geni 3'UTR Varyasyonlarıın mRNA Yıkımı Üzerindeki Etkisi

        EMRENCE Z.

        2.DETAE Günleri, İstanbul, Turkey, 8 - 09 November 2010, pp.64-67, (Full Text)

        Books

        2023

        2023

        1. Polimorfizm ve Mutasyon

        Çakiris A., Emrence Z., Uludağ Alkaya D.

        in: Pediatri Pratiğinde Genetik Testlerin Seçimi ve Yorumlanması, Beyhan Tüysüz, Editor, Nobel Yayınevi, Ankara, pp.15-28, 2023

        Funded Projects

        2025 - 2026

        2025 - 2026

        Tüm Genom Analiz Laboratuvarında Altyapı Eksikliklerine Destek Projesi

        Project Supported by Higher Education Institutions , BAP Infrastructure

        Abacı N. (Executive), Çakiris A., Emrence Z.

        2024 - 2026

        2024 - 2026

        Meme Kanserinde miR30c23p ve m6A Modifikasyonlarının İlişkisinin AraştırılmasıSustainable Development

        Project Supported by Higher Education Institutions , BAP Research Project

        EMRENCE Z. (Executive), PUNAR Ş., USLU S., ZARERAJABI V., ABACI N.

        2025 - 2025

        2025 - 2025

        Hücre Kültürü Laboratuvarı Araştırma Sürekliliği ve Gelişimi

        Project Supported by Higher Education Institutions , BAP Other

        DENİZ G. (Executive), ÇETİN E., EMRENCE Z., KASAP B.

        2021 - 2025

        2021 - 2025

        İnflamazom Aracılı Otoenflamatuvar Hastalıkların Takip ve Tedavisine Yönelik Biyogösterge ve İleri Teknoloji Ürünü İlaçların Geliştirilmesi

        TUBITAK Project , 1004 - Mükemmeliyet Merkezi Destek Programı FAZ I

        Gül A., Hardal G., Cevher E. (Executive), Üresin A. Y. (Executive), Abacı N. (Executive), Sırma Ekmekci S. (Executive), et al.

        2016 - 2025

        2016 - 2025

        Ailevi Akdeniz Ateşi (AAA) Hastalarında MEFV geni UTR Varyasyonlarının Derin Dizileme ile Taranması

        Project Supported by Higher Education Institutions , BAP Research Project

        ÇAKİRİS A. (Executive), EMRENCE Z., SARIMAN M., ABACI N., SIRMA EKMEKCİ S.

        2023 - 2024

        2023 - 2024

        Tüm Eksom Dizilemesi ile Monogenik ve Kompleks Otoinflamatuvar Hastalık Genlerinin Aranması

        Project Supported by Higher Education Institutions , BAP Other

        GÜL A. (Executive), ABACI N., SIRMA EKMEKCİ S., EMRENCE Z.

        2017 - 2020

        2017 - 2020

        T Hücreli Lösemide HEP27nin hücre bölünmesi ve apoptozu üzerine etkisi

        Project Supported by Higher Education Institutions , BAP Other

        ABACI N. (Executive), SIRMA EKMEKCİ S., ÇAKİRİS A., EMRENCE Z.

        2017 - 2018

        2017 - 2018

        CEBPbeta transkripsiyon faktörünün MN1 ekspresyonu üzerindeki etkisinin araştırılması

        Project Supported by Higher Education Institutions , BAP Other

        SIRMA EKMEKCİ S. (Executive), EMRENCE Z., SARIMAN M., ABACI N.

        2016 - 2017

        2016 - 2017

        Klinik bulguları ağır seyreden Ailevi Akdeniz Ateşi Hastalarında MEFV dışı genlerin araştırılması

        Project Supported by Higher Education Institutions , BAP Research Project

        ABACI N. (Executive), ÇAKİRİS A., EMRENCE Z., SIRMA EKMEKCİ S.

        2015 - 2016

        2015 - 2016

        Tanımlanamayan kalıtsal otoinflamatuar hastalıklarda patogenez ile ilişkili aday genlerin araştırılması

        Project Supported by Higher Education Institutions , BAP Research Project

        SIRMA EKMEKCİ S. (Executive), ABACI N., ÇAKİRİS A., EMRENCE Z.

        2015 - 2016

        2015 - 2016

        Nukleer Protein 7 Geninin All-Trans Retinoik Asit Tedavisindeki Rolü

        Project Supported by Higher Education Institutions , BAP PhD

        SIRMA EKMEKCİ S. (Executive), EMRENCE Z.

        2015 - 2016

        2015 - 2016

        Akut Myeloid Lösemide Yüksek düzeyde eksprese olan Mn1 geninin Transkripsiyonunun düzenlenmesi

        TUBITAK Project , 3001 - Initial R&D Projects Support Program

        Sırma Ekmekci S. (Executive), Abacı N., Paçal F., Emrence Z.
        

        Congress and Symposium Activities

        24 May 2025 - 27 May 2025

        24 May 2025 - 27 May 2025

        the European Human Genetics Conference 2025

        Attendee

        Milan-Italy

        26 October 2023 - 29 October 2023

        26 October 2023 - 29 October 2023

        18. Tıbbi Biyoloji ve Genetik Kongresi

        Attendee

        Ankara-Turkey

        18 September 2019 - 22 September 2019

        18 September 2019 - 22 September 2019

        1th International Multidisciplinary Cancer Research CongressSustainable Development

        Attendee

        Diyarbakır-Turkey

        01 October 2017 - 01 October 2017

        01 October 2017 - 01 October 2017

        XV.Ulusal Tıbbi Biyoloji ve Genetik Kongresi

        Attendee

        Muğla-Turkey

        01 May 2017 - 01 May 2017

        01 May 2017 - 01 May 2017

        The European Human Genetics Conference, 2017

        Attendee

        København-Denmark

        01 November 2010 - 01 November 2010

        01 November 2010 - 01 November 2010

        2.DETAE Günleri

        Attendee

        İstanbul-Turkey

        01 September 2010 - 01 September 2010

        01 September 2010 - 01 September 2010

        Autoinflammation 2010

        Attendee

        Amsterdam-Netherlands

        Scholarships

        2010 - 2016

        2010 - 2016

        BİDEB 2211

        TUBITAK

        2008 - 2010

        2008 - 2010

        BİDEB 2210

        TUBITAK

        Citations

        Total Citations (WOS): 1205

        h-index (WOS): 11