Metrics
Publication
69
Open Access
3
UN Sustainable Development Goals
Education
2004 - 2010
2004 - 2010Doctorate
Istanbul University, Institute of Graduate Studies In Sciences, Moleküler Biyoloji Ve Genetik Bölümü, Moleküler Biyoloji Ve Genetik Anabilidalı, Turkey
2001 - 2004
2001 - 2004Postgraduate
Istanbul University, Institute of Graduate Studies In Sciences, Biyoloji Bölümü, Moleküler Biyoloji Ve Genetik Anabilimdalı, Turkey
1997 - 2001
1997 - 2001Undergraduate
Istanbul University, Faculty of Science, Biyoloji, Turkey
Dissertations
2010
2010Doctorate
"Glioma Hücrelerinde İndometasinin Meydana Getirdiği Moleküler Hasarlar Üzerine E Vitamininin Etkileri"
Istanbul University, Fen Fakültesi, Fen Bilimleri Enstitüsü, Moleküler Biyoloji Ve Genetik Bölümü/Moleküler Biyoloji Ve Genetik Anabilimdalı
2004
2004Postgraduate
"Oksidatif Stres Uygulanmış Schizosaccharomycespombe’de Moleküler Çalışmalar"
Istanbul University, Fen Fakültesi, Fen Bilimleri Enstitüsü, Biyoloji Bölümü, Moleküler Biyoloji Ve Genetik Anabilimdalı
Foreign Languages
B2 Upper Intermediate
B2 Upper IntermediateEnglish
Research Areas
Life Sciences
Molecular Biology and Genetics
Moleculer Biology of Cancer
Natural Sciences
Research Areas Based on Academic Activities
Avesis Research Areas
WoS Research Areas
Scopus Research Areas
Academic Positions
2018 - Present
2018 - PresentAssistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
2006 - Present
2006 - PresentResearch Assistant
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
2017 - 2018
2017 - 2018Assistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
Managerial Experience
2018 - Present
2018 - PresentDeputy Head of Department
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
Supervised Theses
in Progress
in ProgressPostgraduate
Cerulenin Uygulanmış U87 Glioblastoma Hücre Hattında Endoplazmik Retikulum Stresinin Araştırılması
Pekmez M. (Advisor)
Ş.Beyza(Student)
2019
2019Postgraduate
The effects of temozolomide on exosomal stress proteins in glioma cells / Temozolomidin glioma hücrelerindeki eksozomal stres proteinleri üzerine etkileri
Pekmez M. (Advisor)
C.Kılcı(Student)
Articles
All (40)
SCI-E, SSCI, AHCI (35)
SCI-E, SSCI, AHCI, ESCI (36)
ESCI (1)
Scopus (36)
TRDizin (4)
Other Publications (1)
2025
20251. Integrated fluorescent sensing of hypochlorite using a carbazole platform: cellular imaging, environmental monitoring, and smartphone analysis
SUNA G., Erdemir E., Hamur B., Aksüt Y., Şengelen A., PEKMEZ M., et al.
Microchemical Journal
, vol.219, 2025 (SCI-Expanded, Scopus)
2025
20252. Spatial Distribution and Contamination of Microplastics in Surface Sediments: A Case Study from Menekşe Beach, Marmara Sea, Türkiye
Korkmaz Y., SARI E., ARSLAN KAYA T. N., Gul M., PEKMEZ M., Sezer N.
WATER AIR AND SOIL POLLUTION
, vol.237, no.3, 2025 (SCI-Expanded, Scopus)
2025
20253. Methotrexate-loaded Sr-BDC metal-organic frameworks attenuate glioblastoma and cervical-carcinoma cells and spheroids’ growth and motility by reducing the inflammation-EMT axis and inducing apoptosis
YILDIRIM E., Şengelen A., YÜCEL O., Aksüt Y., Öğütcü İ., Bayrakçı A., et al.
Journal of Drug Delivery Science and Technology
, vol.111, 2025 (SCI-Expanded)
2025
20254. Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis
PEKMEZ M., Mete S. B., Aksut Y., Ogutcu I., BAŞTÜRK F. N., GERÇEK Y. C., et al.
MEDICAL ONCOLOGY
, vol.42, no.5, 2025 (SCI-Expanded, Scopus)
2025
20255. ANTHOCYANIN ACCUMULATION AND GENE EXPRESSION ANALYSIS IN BLACK CARROT CALLI UNDER SALT AND SALICYLIC ACID STRESSES
Odabasi B., Sebikbay S., Uner A., Yildirim-Bastemur G., Pekmez M., Perçin Özkorucuklu S., et al.
JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS
, vol.35, no.2, pp.445-457, 2025 (SCI-Expanded)
2025
20256. Indomethacin-encapsulated PLGA nanoparticles improve therapeutic efficacy by increasing apoptosis and reducing motility in glioblastoma cells
Pekmez M., Bostancı F., Şengelen A., Aksüt Y., Yıldırım E., Öğütçü İ., et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
, vol.10, no.1, pp.1-12, 2025 (SCI-Expanded)
2025
20257. Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance proteins
Aksüt Y., Şengelen A., Gürsoy D. M., Öğütcü İ., Kuvet Ö., PEKMEZ M.
Frontiers in Pharmacology
, vol.16, 2025 (SCI-Expanded)
2024
20248. Development of recombinant protein-based nanoparticle systems for inducing tumor cell apoptosis: In vitro evaluation of their cytotoxic and apoptotic effects on cancer cells
Kaplan Ö., GÖK M. K., PEKMEZ M., Erden Tayhan S., Özgümüş S., Gökçe İ., et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
, vol.95, 2024 (SCI-Expanded, Scopus)
2024
20249. Cumin Seed Oil Induces Oxidative Stress-Based Antifungal Activities on Fusarium graminearum
Yörük E., Danışman Z., PEKMEZ M., Yli-Mattila T.
Pathogens
, vol.13, no.5, 2024 (SCI-Expanded)
2024
202410. Phytochemical profiling, in vitro biological activities, and in silico (molecular docking and absorption, distribution, metabolism, excretion, toxicity) studies of Polygonum cognatum Meissn
Akpinar R., YILDIRIM BAŞTEMUR G., BIÇAK B., ŞANLI N. Ö., MERTOĞLU KAMALI E., PEKMEZ M., et al.
JOURNAL OF SEPARATION SCIENCE
, vol.47, 2024 (SCI-Expanded, Scopus)
2023
202311. The combined effects of polyethylene microplastics and benzoanthracene on Manila clam Ruditapes philippinarum
Kılıç Ö., Belivermiş M., Sıkdokur E., Sezer N., Aksüt Y., Pekmez M., et al.
CHEMOSPHERE
, vol.329, 2023 (SCI-Expanded, Scopus)
2023
202312. Hyperglycemia with or without insulin resistance triggers different structural changes in brain microcirculation and perivascular matrix
Ozkan E., Cetin-Tas Y., Sekerdag E., Yigit B., Shomalizadeh N., Sapanci S., et al.
METABOLIC BRAIN DISEASE
, vol.38, no.1, pp.307-321, 2023 (SCI-Expanded, Scopus)
2022
202213. The effect of temozolomide on Hsp60 and Hsp70 expression in extracellular vesicles derived from U87MG glioma cells
PEKMEZ M., Kilci C.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
, vol.47, no.1, pp.85-95, 2022 (SCI-Expanded, Scopus, TRDizin)
2021
202114. Identification of natural compounds of Jurinea species by LC-HRMS and GC-FID and their bioactivities
Boke Sarikahya N., Sumer Okkali G., Celenk V. U., Mertoğlu E., Pekmez M., Arda N., et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
, vol.202, 2021 (SCI-Expanded, Scopus)
2021
202115. Intranasal levosimendan prevents cognitive dysfunction and apoptotic response induced by repeated isoflurane exposure in newborn rats
Demirgan S., Akyol O., Temel Z., Sengelen A., Pekmez M., Ulas O., et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
, vol.394, pp.1553-1567, 2021 (SCI-Expanded, Scopus)
2021
202116. The relationship between DIRAS1 gene and idiopathic generalized epilepsy in the Turkish population
Kaplan Ö., Pekmez M., Akinci Y., Atakli H. D., Eren F., Dirican A. C., et al.
GENE REPORTS
, vol.23, 2021 (ESCI)
2021
202117. Effects of Scilla autumnalis Extracts on U87-MG Human Glioblastoma Cells
Pekmez M., Tarhan Ç., Zeytunluoğlu A., Turan M., Mete Ş. B., Köseler A.
Kafkas Tıp Bilimleri Dergisi , vol.11, no.2, pp.299-306, 2021 (Peer-Reviewed Journal)
2020
202018. Evaluation of In vitro Wound Healing Activity of Thymoquinone
Pekmez M., Milat N. S.
European Journal of Biology , vol.72, no.2, pp.151-156, 2020 (Peer-Reviewed Journal)
2020
202019. Effects of microplastics and mercury on manila clam Ruditapes philippinarum: Feeding rate, immunomodulation, histopathology and oxidative stress
Sıkdokur E., Belivermiş M., Sezer N., Pekmez M., Bulan Ö. K., Kılıç Ö.
Environmental Pollution
, vol.262, 2020 (SCI-Expanded, Scopus)
2019
201920. Proteomic identification of allergenic proteins of Morus alba L. pollen
Cetereisi D., Karlıoğlu Kılıç N., Gelincik A., Michelland S., Onay-Ucar E., Ertek B., et al.
ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY
, vol.37, pp.205-211, 2019 (SCI-Expanded, Scopus)
2019
201921. Can Hsp Targeted Gene Therapy Be a New Hope for Gliomas?
Onay-Ucar E., Sengelen A., Gungor E., Mertoglu E., Pekmez M., Arda N.
HEAT SHOCK PROTEINS IN NEUROSCIENCE
, vol.20, pp.209-230, 2019 (SCI-Expanded)
2019
201922. Isoflurane exposure in infant rats acutely increases aquaporin 4 and does not cause neurocognitive impairment
DEMIRGAN S., AKYOL O., Temel Z., Sengelen A., Pekmez M., Demirgan R., et al.
BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES
, vol.19, no.3, pp.257-264, 2019 (SCI-Expanded, Scopus)
2017
201723. Classical Galactosemia: Insight into Molecular Pathomechanisms by Differential Membrane Proteomics of Fibroblasts under Galactose Stress
Staubach S., Mueller S., Pekmez M., Hanisch F.
JOURNAL OF PROTEOME RESEARCH
, vol.16, no.2, pp.516-527, 2017 (SCI-Expanded, Scopus)
2017
201724. The structure and cytotoxic activity of a new saponin: cephoside A from Cephalaria elazigensis var. purpurea
Kayce P., Sarikahya N. B., Pekmez M., Arda N., Kirmizigul S.
TURKISH JOURNAL OF CHEMISTRY
, vol.41, no.3, pp.345-353, 2017 (SCI-Expanded, Scopus, TRDizin)
2016
201625. Differential Proteomics of Urinary Exovesicles from Classical Galactosemic Patients Reveals Subclinical Kidney Insufficiency
Staubach S., Pekmez M., Hanisch F.
JOURNAL OF PROTEOME RESEARCH
, vol.15, no.6, pp.1754-1761, 2016 (SCI-Expanded, Scopus)
2016
201626. IN VITRO ANTICANCER ACTIVITY AND CYTOTOXICITY OF SOME PAPAVER ALKALOIDS ON CANCER AND NORMAL CELL LINES
Demirgan R., Karagoz A., Pekmez M., Onay-Ucar E., Artun F. T., Gurer Ç., et al.
AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES
, vol.13, no.3, pp.22-26, 2016 (SCI-Expanded, Scopus)
2015
201527. Effect of alpha-tocopheryl succinate on the molecular damage induced by indomethacin in C6 glioma cells
Pekmez M., Onay-Ucar E., Arda N.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
, vol.9, no.2, pp.585-590, 2015 (SCI-Expanded, Scopus)
2014
201428. Comparison of antioxidant capacity, protein profile and carbohydrate content of whey protein fractions
Onay-Ucar E., Arda N., Pekmez M., Yilmaz A. M., Boke-Sarikahya N., Kirmizigul S., et al.
FOOD CHEMISTRY
, vol.150, pp.34-40, 2014 (SCI-Expanded, Scopus)
2014
201429. Evaluation of biological activities of Physalis peruviana ethanol extracts and expression of Bcl-2 genes in HeLa cells
Cakir O., Pekmez M., Cepni E., Candar B., Fidan K.
FOOD SCIENCE AND TECHNOLOGY
, vol.34, no.2, pp.422-430, 2014 (SCI-Expanded, Scopus)
2012
201230. Investigation of the Relationship Between Oxidative Stress and Glucose Signaling in Schizosaccharomyces pombe
Palabiyik B., Kig C., Pekmez M., Dalyan L., Arda N., Temizkan G.
BIOCHEMICAL GENETICS
, vol.50, no.5-6, pp.336-349, 2012 (SCI-Expanded, Scopus)
2012
201231. Fatty Acid Profile and Biological Data of Four Endemic Cephalaria Species Grown in Turkey
Kirmizigul S., SARIKAHYA N., SÜMBÜL H., GÖKTÜRK R. S., Yavasoglu N. U. K., Pekmez M., et al.
RECORDS OF NATURAL PRODUCTS
, vol.6, no.2, pp.151-155, 2012 (SCI-Expanded, Scopus)
2011
201132. Isolation and characterization of biologically active glycosides from endemic Cephalaria species in Anatolia
Sarikahya N. B., Pekmez M., Arda N., Kayce P., Yavasoglu N. U. K., Kirmizigul S.
PHYTOCHEMISTRY LETTERS
, vol.4, no.4, pp.415-420, 2011 (SCI-Expanded, Scopus)
2011
201133. Total phenolic contents, antioxidant activities and cytotoxicity of three Centaurea species: C. calcitrapa subsp. calcitrapa, C. ptosimopappa and C. spicata
Erol-Dayi Ö., PEKMEZ M., Bona M., Aras-Perk A., ARDA E. Ş. N., ARAS PERK A.
Free Radicals and Antioxidants , vol.1, no.2, pp.31-36, 2011 (Peer-Reviewed Journal)
2010
201034. Antioxidant and Cytotoxic Activities of Aphanes arvensis Extracts
Hamad I., Erol-Dayi O., Pekmez M., Onay-Ucar E., Arda N.
PLANT FOODS FOR HUMAN NUTRITION
, vol.65, no.1, pp.44-49, 2010 (SCI-Expanded, Scopus)
2010
201035. Expression of Human A4V Mutant Cu,Zn Superoxide Dismutase in Schizosaccharomyces pombe: Investigations of its Toxic Properties
Karaer S., Tarhan C., Pekmez M., HAMAD I., Arda N., Sarikaya A. T.
BIOCHEMICAL GENETICS
, vol.48, no.1-2, pp.113-124, 2010 (SCI-Expanded, Scopus)
2010
201036. Intracellular scavenging activity of Trolox (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid) in the fission yeast, Schizosaccharomyces pombe
Hamad İ., Arda N., PEKMEZ M., Karaer S., Temizkan G.
Journal of Natural Science Biology and Medicine , vol.1, no.1, pp.16-21, 2010 (Scopus)
2009
200937. Fatty Acid Profile and in vitro Antioxidant and Antibacterial Activities of Red Grape (Vitis vinifera L. cvs. Okuzgozu and Bogazkere) Marc Extracts
Cibik B., Oezaydin Z., Boeke N., Karabay U., Pekmez M., Arda N., et al.
NATURAL PRODUCT COMMUNICATIONS
, vol.4, no.3, pp.399-404, 2009 (SCI-Expanded, Scopus)
2008
200838. Antioxidant activity of whey protein fractions isolated by gel exclusion chromatography an protease treatment
Bayram T., Pekmez M., Arda N., YALÇIN A. S.
TALANTA
, vol.75, no.3, pp.705-709, 2008 (SCI-Expanded, Scopus)
2008
200839. Hydrogen peroxide-induced oxidative damages in Schizosaccharomyces pombe
Pekmez M., Arda N., Hamad I., Kig C., Temizkan G.
BIOLOGIA
, vol.63, no.2, pp.151-155, 2008 (SCI-Expanded, Scopus)
2007
200740. The effect of superoxide dismutase deficiency on zinc toxicity in Schizosaccharomyces pombe
Tarhan C., Pekmez M., Karaer S., Arda N., Sarikaya A. T.
JOURNAL OF BASIC MICROBIOLOGY
, vol.47, no.6, pp.506-512, 2007 (SCI-Expanded, Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2022
20221. Tiroid Kanseri Hücrelerinde N-bağlı Glikoproteinlerin Glikomik Analizi Yeni Potansiyel Terapötik ve Tanısal Hedefleri İşaret Eder
Bektaş S., Pekmez M., Şanlı K., Sancar S., Arda Pirinççi B. P., Arda E. Ş. N., et al.
11. ULUSAL MOLEKÜLER BİYOLOJİ VE BİYOTEKNOLOJİ KONGRESİ, İstanbul, Turkey, 7 - 09 October 2022, pp.67, (Summary Text)
2021
20212. İnsan anaplastik tiroit kanserinde Maackia amurensis Lökoaglutinin uygulaması sağkalım yolaklarının etkinliğini ve EMT ilişkili transkripsiyon faktörlerini baskılar
Bektaş S., Sancar S., Pekmez M., Arda Pirinççi B. P., Kaptan E.
10. ULUSAL MOLEKÜLER BİYOLOJİ VE BİYOTEKNOLOJİ KONGRESİ, İstanbul, Turkey, 17 - 19 December 2021, pp.32, (Summary Text)
2020
20203. POTENTIAL APPLICATIONS OF PLANT LECTINS AGAINST SARS-CoV-2
Pekmez M.
The Sixth International Mediterranean Symposium on Medicinal and Aromatic Plants, İzmir, Turkey, 15 - 17 October 2020, pp.40, (Summary Text)
2019
20194. Investigation of Thymoquinone usability on wound healing
Milat N. S., Şengelen A., PEKMEZ M.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, vol.43, no.5, pp.10, (Full Text)
2019
20195. Suppression of Hsp60 and Hsp70 increases the anti-tumor effectsof resveratrol in human glioblastoma cells
Önay Uçar E., Şengelen A., Mertoğlu E., Pekmez M., Arda E. Ş. N.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, no.36, pp.100, (Summary Text)
2019
20196. Investigation of cytotoxic activity of cerulenin and vitamin E combination in U87 glioma cell line
Uzunalioğlu N., MERTOĞLU E., PEKMEZ M.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, no.42, pp.106, (Full Text)
2017
20177. The effects of vitamin E on molecular damages induced by indomethacin in glioma cells
ARDA E. Ş. N., PEKMEZ M., ÖNAY UÇAR E.
EACR-AACR-SIC SPECIAL CONFERENCE 2017, Floransa, Italy, 24 - 27 June 2017, pp.105, (Full Text)
2016
20168. Protective effects of Sanicula europaea extracts on nuclear DNA damage
ÖNAY UÇAR E., PEKMEZ M., MERTOĞLU E., Dalyan L., ARDA E. Ş. N.
24th Biennial Congress of the European Association for Cancer Research, Manchester, United Kingdom, 9 - 12 July 2016, vol.61, no.1, (Full Text)
2013
20139. Cytotoxic Effects Of Physalis Peruviana Ethanol Extracts On Hela Cells
Fidan K., Candar Çakır B., PEKMEZ M., ÇAKIR Ö.
1st Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-2013), Cyprus (Kktc), 1 - 04 April 2013, pp.240, (Full Text)
2011
201110. The effects of Alpha-Tocopheryl Succinate on Molecular Damages Induced by Indomethacin and on Apoptosis in C6 Glioma Cells
PEKMEZ M., Oktay Z., Açılan Ayhan C., ARDA E. Ş. N.
EACR-ANTICANCER AGENTS RESEARCH CONGRESS, Antalya, Turkey, 13 - 16 October 2011, pp.54-55, (Full Text)
2011
201111. Oxidative stress studies with IMPDH-overexpressed S. pombe
Karaer Uzuner S., Seven M., Şişko S., PALABIYIK B., Pekmez M., Topal Sarıkaya A.
The 6th International Fission Yeast Meeting, United States Of America, 1 - 04 June 2011, vol.1, pp.232, (Full Text)
2009
200912. Antioxidant activity of whey and whey hydrolysates.
Arda E. Ş. N., Önay Uçar E., Pekmez M., Yılmaz A. M., Yalçın A. S.
34th FEBS Congress, Praha, Czech Republic, 4 - 09 July 2009, pp.299, (Summary Text)
2007
200713. Free radical scavenging activity and protective effects of Alchemilla vulgaris (L.)
Hamad I., EROL-DAYI O., Pekmez M., Onay-Ucar E., Arda N.
13th European Congress on Biotechnology (ECB 13), Barcelona, Spain, 16 - 19 September 2007, vol.131, (Summary Text)
2007
200714. Fission yeast as a model for ALS disease
Karaer S., Tarhan C., Hamad I., Pekmez M., Arda N., Sarikaya A. T.
13th European Congress on Biotechnology (ECB 13), Barcelona, Spain, 16 - 19 September 2007, vol.131, (Summary Text)
2006
200615. Antioxidant potential of whey protein fractions
Bayram T., Pekmez M., Onay-Ucar E., Arda N., YALCIN S.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Turkey, 24 - 29 June 2006, vol.273, pp.299, (Summary Text)
2005
200516. Studying on Zinc Toxicty and Antioxidant Defense Mechanism in Schizosaccharomyces pombe
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
The XXIInd International Conference on Yeast Genetics and Molecular Biiology, Slovakia, 1 - 04 September 2005, pp.36, (Full Text)
2005
200517. Çinko Toksisitesi ve Antioksidan Savunma Mekaniizmaları Üzerine Çlaışmalar
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
XIV. Ulusal Biyoteknoloji Kongresi, Eskişehir, Turkey, 1 - 04 September 2005, pp.322, (Full Text)
2002
200218. Ökseotunun (Viscum album ssp.album) Pigment İçeriği Üzerinde Konakçı Ağaçların Etkisi
Pekmez M., Önay Uçar E., Arda E. Ş. N.
XVI. Ulusal Biyoloji Kongresi, Malatya, Turkey, 4 - 07 September 2002, pp.173, (Summary Text)
2002
200219. Antioxidant potential of Some Turkish Medicinal Plants
Arda E. Ş. N., Önay Uçar E., Pekmez M., Karagöz A.
2rd International Meeting on Free adicals in Health and Disease, İstanbul, Turkey, 8 - 12 May 2002, pp.2, (Summary Text)
Books
2023
20231. Exosomal Heat Shock Proteins in Cancer
Önay Uçar E., Mertoğlu Kamalı E., Kıyga E., Şengelen A., Pekmez M., Arda E. Ş. N.
in: Heat Shock Proteins (HSP) in Cellular Communication and Signaling, Heat Shock Proteins Volume 26, Alexzander A.A. Asea,Punit Kaur, Editor, Scientific Scholar LLC, New York, pp.139-152, 2023
2022
20222. Bölüm 11 Yeni Virüslerin Ortaya Çıkışı
Arda E. Ş. N., Önay Uçar E., Pekmez M.
in: Virolojinin Prensipleri Cilt II Patogenez ve Kontrol, Hikmet Geçkil,Ekrem Atalan, Editor, Palme Yayın Dağıtım, Ankara, pp.362-385, 2022
2022
20223. Bölüm 12 Hücre İçi Trafik
Arda E. Ş. N., Önay Uçar E., Pekmez M.
in: Virolojinin Prensipleri Beşinci Baskıdan Çeviri CİLT I Moleküler Biyoloji, Hikmet Geçkil, Editor, Palme Yayın Dağıtım, Ankara, pp.399-432, 2022
2022
20224. What We Know About the Role of Heat Shock Proteins in Coronavirus Infection: A Remarkable Prognostic Factor or a Therapeutic Strategy?
ŞENGELEN A., DEMİRGAN S., Aksüt Y., PEKMEZ M., ARDA E. Ş. N., ÖNAY UÇAR E.
in: Heat Shock Proteins (HSP) and Coronavirus, Heat Shock Proteins Volume 25, Asea Alexzander A.A., Kaur Punit, Editor, ISBN: 979-8-9873112-0-2, pp.36-65, 2022
2019
20195. Can Hsp Targeted Gene Therapy Be a New Hope for Gliomas?
ÖNAY UÇAR E., Şengelen A., Güngör E., MERTOĞLU E., PEKMEZ M., ARDA E. Ş. N.
in: Heat Shock Proteins in Neuroscience, Heat Shock Proteins Volume 20, Asea A.A.A., Kaur P., Editor, Springer-Verlag , Cham, pp.209-230, 2019
2018
20186. Suppression of HSP70 Expression by Quercetin and Its Therapeutic Potential Against Cancer
Önay Uçar E., Şengelen A., Mertoğlu E., Pekmez M., Arda N.
in: HSP70 in Human Diseases and Disorders, Asea A.A.A.,Kaur P., Editor, Springer, Zug, pp.361-379, 2018
2018
20187. HSP70 in Human Diseases and Disorders
Önay Uçar E., Şengelen A., Mertoğlu E., Pekmez M., Arda E. Ş. N.
in: Suppression of HSP70 Expression by Quercetin and Its Therapeutic Potential Against Cancer, Asea A.A.A,Kaur P., Editor, Springer, London/Berlin , Zug, pp.361-379, 2018
2017
20178. Biyoteknolojide Proteomik Uygulamaları
ARDA E. Ş. N., ÖNAY UÇAR E., PEKMEZ M.
in: Güncel Biyoteknoloji ve Uygulamaları, Munis Dündar, Haydar Bağış, Editor, Erciyes Üniversitesi Yayınları, Kayseri, pp.279-294, 2017
2017
20179. Targeting of Heat Shock Proteins by Natural Products in Cancer
ÖNAY UÇAR E., PEKMEZ M., ARDA E. Ş. N.
in: Molecular Oncology: Underlying Mechanisms and Translational Advancements, Farooqi A.A., Ismail M., Editor, Springer-Verlag , Cham, pp.173-193, 2017
2017
201710. Targeting of Heat Shock Proteins by Natural Products in Cancer
ÖNAY UÇAR E., PEKMEZ M., ARDA E. Ş. N.
in: Molecular Oncology: Underlying Mechanisms and Translational
Advancements, Farooqi A.A., Ismail M., Editor, Springer-Verlag , Cham, pp.173-193, 2017
Funded Projects
2023 - 2024
2023 - 2024Paxlovidin Caco2 Hücre Hattında Otofajiye Olan Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), ÖZYILDIZ İ. Ş., BALIKÇI S., ŞİMŞEK G.
2022 - 2024
2022 - 2024Absans epilepsili sıçanlarda T-tipi Ca+2 kanal protein ekspresyonunun araştırılması
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), MUTLU N., ONAT F.
2022 - 2024
2022 - 2024
Anti Kanser İlaç Direnç Mekanizmasında Isı Şoku Proteinlerinin Şaperon Aktivitesinin Araştırılması
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), AKSOY D. M.
2023 - 2023
2023 - 20231415EET (1415epoxy5Z8Z11Zeicosatrienoic acid)'nin İnsan Fibroblast Hücre Hattı Üzerinde Yara İyileştirici Etkisinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), TEKİN F. M.
2022 - 2023
2022 - 2023"Daucus carota ssp sativus var atrorubens" Ekstresinin Antioksidan Aktivitesinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), ÜNER A.
2022 - 2023
2022 - 2023Denizel canlı kaynaklardan izole edilen glikozaminoglikanların insan glioblastoma U87MG hücreleri üzerindeki etkilerinin araştırılması
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), AKSOY N. B.
2022 - 2023
2022 - 2023Nanopartiküler Taşıyıcı Sistem Aracılığıyla İndometasinin İnsan Glioblastoma U87MG Hücreleri Üzerindeki Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), BOSTANCI F.
2021 - 2023
2021 - 2023İndometasin Uygulanmış U87 Glioma Hücrelerinde Endoplazmik Retikulum Stresi ile İlişkili miRNAların Analizi
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), ULAŞ O.
2020 - 2023
2020 - 2023Benzotiyazolin Artığı Taşıyan Spiroindolinonlar: Sentez Yapı Tayini ve Biyolojik Etki Araştırmaları
Project Supported by Higher Education Institutions , BAP Research Project
KARALI N. L. (Executive), TEMİZER A. B., ÖZSOY N., ARDA E. Ş. N., ANDAÇ Ö., KARABAĞ N., et al.
2019 - 2023
2019 - 2023
Mcl-1 Protein İnhibitörü Yüklü Nanopartiküllerin Kanser Hücreleri Üzerindeki Sitotoksik ve Apoptotik Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
ARDA E. Ş. N. (Executive), PABUCCUOĞLU S. K., PEKMEZ M., KAPLAN Ö., MERTOĞLU E., GÖK M. K., et al.
2019 - 2023
2019 - 2023Nuclear Techniques to Assess the Effect of Coastal Stressors on Marine Organisms
IAEA International Atomic Energy Agency Supportted Project
Pekmez M., Kılıç Ö. (Executive), Belivermiş M., Kaptan E.
2022 - 2022
2022 - 2022Ticari Balık Atıklarından Elde Edilen Glikozaminoglikanların İnsan Glioblastoma U87MG Hücreleri Üzerindeki Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), KOÇ R. G., AKTAR D.
2022 - 2022
2022 - 2022Polygonum cognatum Meissn'in HepG2 Hücre Hattında Metastaz İnhibisyonu ve Bax ile Bak Ekspresyonları Üzerine etkilerinin araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), DEMİRCİ Z.
2021 - 2022
2021 - 2022Camponotus floridanus'ta BMP Sinyalizasyonu ve Zorunlu Endosimbiyont Varlığında Değişimi
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), MİLAT N. S., RAFİQİ A. M.
2019 - 2022
2019 - 2022Cerulenin Uygulanmış U87 Glioblastoma Hücre Hattında Endoplazmik Retikulum Stresinin Araştırılması
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), METE Ş. B.
2019 - 2022
2019 - 2022Mikroplastik ve PAH Benzo(a)antrasen'in tek ve birleşik toksik etkilerinin Manila kum midyesi Ruditapes philippinarumda araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
KILIÇ Ö. (Executive), BELİVERMİŞ M., KÖSESAKAL T., SEZER N., SIKDOKUR E., PEKMEZ M.
2018 - 2022
2018 - 2022Balıkçılıkta Iskarta Av Grubu Türlerin Kollajen Karakterizasyonu ve Potansiyel Kullanımı
Project Supported by Higher Education Institutions , BAP Research Project
YEMİŞKEN E. (Executive), SANCAR BAŞ S., PEKMEZ M., MENCELOĞLU Y., AVAZ M. S.
2020 - 2021
2020 - 2021U87 glioblastoma hücre hattında alternatif antijen sunum yolağının şaperon aktivitesi tayini
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), KUGU S., AKSOY D. M., SUCU M. C.
2020 - 2021
2020 - 2021
Tip 1 diabetes mellitus hayvan modelinde beyinde ekstraselüler matris
moleküllerinden kollajen tip 1 anlatımının araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), KIZILIRMAK A. B.
2018 - 2021
2018 - 2021Hsp-spesifik siRNA ve Antioksidan Ajan Kombine Terapisinin Beyin Tümör Hücreleri Üzerindeki Etkileri
Project Supported by Higher Education Institutions , BAP Research Project
ÖNAY UÇAR E. (Executive), PEKMEZ M., MERTOĞLU E., GÜNGÖR E., ŞENGELEN A., ARDA E. Ş. N.
2019 - 2019
2019 - 2019U87 glioma hücre hattında Cerulenin ve Vitamin C kombinasyonunun sitotoksik aktivitesinin incelenmesi
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), UZUNALİOĞLU N.
2018 - 2019
2018 - 2019Nigella sativa Etken Maddesi Timokinonun Fibroblast Kültüründeki Sitotoksisitesinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
PEKMEZ M. (Executive), MİLAT N. S.
2018 - 2019
2018 - 2019Temozolomidin Glioma Hücrelerindeki Eksozomal Stres Proteinleri Üzerine Etkileri
Project Supported by Higher Education Institutions , BAP MSc
PEKMEZ M. (Executive), KILCI C.
2017 - 2019
2017 - 2019Aubrieta ekimiinin Çeşitli Biyolojik Aktivitelerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
ÇEPNİ YÜZBAŞIOĞLU F. E. (Executive), YÜZBAŞIOĞLU İ. S., TURGUT KARA N., ÇAKIR Ö., PEKMEZ M., ARIKAN B., et al.
2016 - 2018
2016 - 2018Tenacibaculum maritimum izolatlarının filogenetik ve enzimatik karaterlerinin incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
STEINUM T. M. (Executive), KARATAŞ STEINUM S., ARDA E. Ş. N., YARDIMCI R. E., PEKMEZ M., TURGAY E., et al.
2016 - 2018
2016 - 2018BİTKİSEL BİYOAKTİF BİLEŞİKLERE AİT KÜTLE SPEKTRUMLARININ GÜNCEL VERİ TABANLARINDA (MS KÜTÜPHANELERİNDE) TARANMASI
Project Supported by Higher Education Institutions , BAP Research Project
ARDA E. Ş. N. (Executive), PEKMEZ M., ÖNAY UÇAR E., YİĞİT H.
2017 - 2017
2017 - 2017The Effects of Vitamin E on Molecular Damages Induced by Indomethacin in Glioma Cells
Project Supported by Higher Education Institutions , BAP Other
ARDA E. Ş. N. (Executive), PEKMEZ M., ÖNAY UÇAR E.
2016 - 2016
2016 - 2016Protective Effects of Sanicula europaea Extracts on Nuclear DNA Damage
Project Supported by Higher Education Institutions , BAP Other
ÖNAY UÇAR E. (Executive), PEKMEZ M., ARDA E. Ş. N., DALYAN L., MERTOĞLU E.
2013 - 2016
2013 - 2016İndometasin ve E vitamini uygulanmış C6 Sıçan Glioma Hücrelerinde Ölüm Mekanizmalarının Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
PEKMEZ M. (Executive), ARDA E. Ş. N.
2013 - 2016
2013 - 2016MOLEKÜLER BİYOTEKNOLOJİ LABORATUVARININ KURULMASI
Project Supported by Higher Education Institutions , BAP Guided
ARDA E. Ş. N. (Executive), UÇARLI C., ARICAN E., ALBAYRAK G., GÜREL A. F., ARI Ş., et al.
2009 - 2014
2009 - 2014İstanbul Park, Bahçe ve Korularındaki Bazı Ağaç Polenlerinin Alerjenitesinin ve İmmunohistokimyasal Özelliklerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
BÜYÜKÖZTÜRK S. (Executive), GELİNCİK A., DENİZ G., ARDA E. Ş. N., ERTEN YURDAGÜL G., PEKMEZ M., et al.
Memberships and Roles in Scientific Organizations
2009 - Present
2009 - PresentSerbest Radikaller ve Antioksidanlar Araştırma Derneği
Member
Peer Reviews in Scientific Publications
April 2010
April 2010African Journal of Biotechnology
National Scientific Refreed Journal
Congress and Symposium Activities
01 April 2013 - 01 April 2013
01 April 2013 - 01 April 20131st Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-2013)
Attendee
-Cyprus (Kktc)
01 October 2011 - 01 October 2011
01 October 2011 - 01 October 2011EACR-Anticancer Agents Research Congress
Attendee
Antalya-Turkey
01 June 2011 - 01 June 2011
01 June 2011 - 01 June 2011The Sixth International Fission Yeast Meeting
Attendee
Boston-United States Of America
01 July 2009 - 01 July 2009
01 July 2009 - 01 July 200934th FEBS Congress
Attendee
Prag-Czech Republic
01 May 2008 - 01 May 2008
01 May 2008 - 01 May 2008I. Ulusal Maya Moleküler Biyolojisi ve Biyoteknoloji Sempozyumu
Attendee
Bursa-Turkey
01 September 2007 - 01 September 2007
01 September 2007 - 01 September 200713th European Congress on Biotechnology
Attendee
Barcelona-Spain
01 September 2006 - 01 September 2006
01 September 2006 - 01 September 20069th Eurasia Conference on Chemical Sciences (EuAs C2S-9)
Attendee
Antalya-Turkey
01 June 2006 - 01 June 2006
01 June 2006 - 01 June 200631th FEBS Congress
Attendee
İstanbul-Turkey
01 September 2002 - 01 September 2002
01 September 2002 - 01 September 2002XVI. Ulusal Biyoloji Kongresi
Attendee
Malatya-Turkey
01 May 2002 - 01 May 2002
01 May 2002 - 01 May 2002