Metrics
Publication
47
Open Access
1
UN Sustainable Development Goals
Education
2012 - 2016
2012 - 2016Doctorate
Istanbul University, Faculty of Pharmacy , Farmakoloji, Turkey
2010 - 2012
2010 - 2012Postgraduate
Istanbul University, Faculty of Pharmacy , Farmakoloji, Turkey
Dissertations
2016
2016Doctorate
Vasküler Homeostaz Üzerine Perivasküler Adipoz Dokunun Fizyolojik ve Patofizyolojik Rolünün İncelenmesi
Istanbul University, Faculty of Pharmacy , Farmakoloji
2012
2012Postgraduate
Koroner Bypass Greft Mataryellerinin Reaktiviteleri Üzerine Perivasküler Adipoz Dokularının Etkisinin İncelenmesi
Istanbul University, Faculty of Pharmacy , Farmakoloji Anabilim Dalı
Research Areas
Health Sciences
Pharmacology and Therapeutics
Professional Sciences
Pharmacology
Research Areas Based on Academic Activities
Avesis Research Areas
WoS Research Areas
Scopus Research Areas
Academic Positions
2018 - Present
2018 - PresentAssistant Professor
Istanbul University, Faculty of Pharmacy , Farmakoloji Anabilim Dalı
2017 - 2018
2017 - 2018Assistant Professor
Istanbul University, Faculty of Pharmacy , Farmakoloji Anabilim Dalı
Non Academic Experience
2019 - 2019
2019 - 2019Doktora sonrası araştırmacı
Université de Paris INSERM U1148 Laboratuvarı, Doktora sonrası araştırmacı
2016 - 2017
2016 - 2017Doktora sonrası araştırmacı
Université de Paris INSERM U1148 Laboratuvarı, Doktora sonrası araştırmacı
2014 - 2015
2014 - 2015Doktora sırasında araştırmacı
Université de Paris INSERM U1148 Laboratuvarı, Doktora sırasında araştırmacı
Articles
All (28)
SCI-E, SSCI, AHCI (23)
SCI-E, SSCI, AHCI, ESCI (27)
ESCI (4)
Scopus (24)
TRDizin (5)
2025
20251. Competency-based pharmacy education: Implementations of performance assessment
Özhan G., Akalın E., Yildizli H., Kurt Şirin Ö., Tuncay H. O., Eter O. S., et al.
ISTANBUL JOURNAL OF PHARMACY
, no.1, pp.18-24, 2025 (ESCI, TRDizin)
2025
20252. Infodemiology Meets Pharmacoepidemiology: Search Trends and National Drug Use Patterns for Pain-related Medications in Türkiye
BADIL GÜLOĞLU S., ÖZEN YORGANCIGİL G., AŞIK H. K., ŞAHBAZ T., FERAHMAN D.
Comprehensive medicine , vol.17, no.4, pp.265-270, 2025 (TRDizin)
2023
20233. Effect of specialized pro-resolving lipid mediators in the regulation of vascular tone and inflammation in human saphenous vein.
Celik Z., Ozen G., Sunar S., Türkyılmaz S., Türkyılmaz G., Kavala A. A., et al.
Prostaglandins & other lipid mediators
, vol.169, pp.106786, 2023 (SCI-Expanded, Scopus)
2022
20224. The biological actions of prostanoids in adipose tissue in physiological and pathophysiological conditions.
Civelek E., Ozen G.
Prostaglandins, leukotrienes, and essential fatty acids
, vol.186, pp.102508, 2022 (SCI-Expanded, Scopus)
2022
20225. Comparative study of coronary artery bypass graft materials: reduced contraction and ADMA levels in internal mammary artery versus saphenous vein.
Ozen G., Aljesri K., Turkyilmaz G., Turkyilmaz S., Kavala A. A., Topal G., et al.
The Journal of cardiovascular surgery
, vol.63, no.1, pp.69-77, 2022 (SCI-Expanded)
2021
20216. Comparative study on the effect of aspirin, TP receptor antagonist and TxA(2) synthase inhibitor on the vascular tone of human saphenous vein and internal mammary artery.
Ozen G., Aljesri K., Abdelazeem H., Norel X., Turkyılmaz G., Turkyılmaz S., et al.
Life sciences
, vol.286, pp.120073, 2021 (SCI-Expanded, Scopus)
2021
20217. MMPs and TIMPs levels are correlated with anthropometric parameters, blood pressure, and endothelial function in obesity
Boumiza S., Chahed K., Tabka Z., Jacob M., Norel X., ÖZEN G.
SCIENTIFIC REPORTS
, vol.11, no.1, 2021 (SCI-Expanded)
2021
20218. In search of pulmonary hypertension treatments: Effect of 17 beta-estradiol on PGI(2) pathway in human pulmonary artery
Amgoud Y., Senbel A., Bouhadoun A., Abdelazeem H., Ozen G., Savane I., et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
, vol.172, 2021 (SCI-Expanded)
2021
20219. Association between synovial fluid prostanoid levels and ultrasonographic findings in knee osteoarthritis
ÖZEN G., ŞEN E. İ., ÇELİK Z., ŞAHBAZ T., TOPAL TANYILMAZ G., DIRAÇOĞLU D.
CUKUROVA MEDICAL JOURNAL
, vol.46, no.3, pp.934-943, 2021 (ESCI, TRDizin)
2020
202010. Mechanism of thromboxane receptor-induced vasoconstriction in human saphenous vein
Ozen G., Aljesri K., Celik Z., Turkyılmaz G., Turkyılmaz S., Teskin O., et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, vol.151, 2020 (SCI-Expanded, Scopus)
2020
202011. Clinical characteristics of patients undergoing coronary artery bypass surgery: Focus on gender differences
ÖZEN YORGANCIGİL G., ALJESRİ K., KIZAR Ö., TOPAL TANYILMAZ G., TÜRKYILMAZ G., TÜRKYILMAZ S.
JOURNAL OF PHARMACY OF ISTANBUL UNIVERSITY , vol.50, no.3, pp.153-159, 2020 (ESCI, TRDizin)
2020
202012. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E-2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
Norel X., Sugimoto Y., Ozen G., Abdelazeem H., Amgoud Y., Bouhadoun A., et al.
PHARMACOLOGICAL REVIEWS
, vol.72, no.4, pp.910-968, 2020 (SCI-Expanded)
2020
202013. Effect of omega-3 polyunsaturated fatty acids in modulation of vascular tone under physiological and pathological conditions.
Daci A., Celik Z., Ozen G., Dashwood M., Dogan B., Topal G.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
, vol.153, pp.105499, 2020 (SCI-Expanded)
2020
202014. Downregulation of PGI(2) pathway in Pulmonary Hypertension Group-III patients
Ozen G., Amgoud Y., Abdelazeem H., Mani S., Benyahia C., Bouhadoun A., et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
, vol.160, 2020 (SCI-Expanded, Scopus)
2020
202015. In Vitro Effects of Eicosapentaenoic and Docosahexaenoic Acid on the Vascular Tone of a Human Saphenous Vein: Influence of Precontractile Agents
Daci A., Ozen G., Karaman E., Teskin O., Caglayan M., Celik Z., et al.
ANNALS OF VASCULAR SURGERY
, vol.64, pp.318-327, 2020 (SCI-Expanded, Scopus)
2020
202016. Interaction between PGI(2) and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients
Ozen G., Benyahia C., Amgoud Y., Patel J., Abdelazeem H., Bouhadoun A., et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, vol.146, 2020 (SCI-Expanded, Scopus)
2019
201917. Bronchodilation induced by PGE(2) is impaired in Group III pulmonary hypertension
Ozen G., Benyahia C., Mani S., Boukais K., Silverstein A. M., Bayles R., et al.
BRITISH JOURNAL OF PHARMACOLOGY
, 2019 (SCI-Expanded)
2019
201918. Inflammation increases MMP levels via PGE(2) in human vascular wall and plasma of obese women
Ozen G., Boumiza S., Deschildre C., Topal G., LONGROIS D., Jakobsson P. J., et al.
INTERNATIONAL JOURNAL OF OBESITY
, vol.43, no.9, pp.1724-1734, 2019 (SCI-Expanded, Scopus)
2017
201719. Omega-3 polyunsaturated fatty acids reduce vascular tone and inflammation in human saphenous vein
Daci A., Ozen G., Uyar I., Civelek E., Yildirim F. İ., Durman D., et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, pp.29-34, 2017 (SCI-Expanded, Scopus)
2017
201720. Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI(2): a safer alternative to COX-2 inhibition
Ozen G., GOMEZ I., Daci A., DESCHILDRE C., BOUBAYA L., TESKIN O., et al.
BRITISH JOURNAL OF PHARMACOLOGY
, vol.174, no.22, pp.4087-4098, 2017 (SCI-Expanded, Scopus)
2017
201721. Prostanoids in the pathophysiology of human coronary artery
Ozen G., NOREL X.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, vol.133, pp.20-28, 2017 (SCI-Expanded)
2017
201722. Decreased vasorelaxation induced by iloprost during acute inflammation in human internal mammary artery
FOUDI N., Ozen G., AMGOUD Y., LOUEDEC L., CHOQUEUX C., BADI A., et al.
EUROPEAN JOURNAL OF PHARMACOLOGY
, vol.804, pp.31-37, 2017 (SCI-Expanded, Scopus)
2016
201623. Reverse Regulatory Pathway (H2S / PGE2 / MMP) in Human Aortic Aneurysm and Saphenous Vein Varicosity.
GOMEZ I., Ozen G., DESCHILDRE C., AMGOUD Y., BOUBAYA L., Gorenne I., et al.
PloS one
, vol.11, no.6, 2016 (SCI-Expanded)
2016
201624. The role of perivascular adipose tissue on human saphenous vein vascular tone
Ozen G., Dogan B. S., Teskin O., Norel X., Topal G.
ISTANBUL JOURNAL OF PHARMACY
, vol.46, no.1, pp.1-13, 2016 (ESCI, Scopus, TRDizin)
2015
201525. Human perivascular adipose tissue dysfunction as a cause of vascular disease: Focus on vascular tone and wall remodeling
Ozen G., Daci A., Norel X., Topal G.
EUROPEAN JOURNAL OF PHARMACOLOGY
, vol.766, pp.16-24, 2015 (SCI-Expanded)
2015
201526. Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents
Benyahia C., Ozen G., Orie N., Ledwozyw A., LOUEDEC L., Li F., et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, vol.121, pp.46-52, 2015 (SCI-Expanded, Scopus)
2014
201427. Resveratrol improves high-fructose-induced vascular dysfunction in rats
Develi-Is S., Ozen G., Bekpinar S., Topal G., Unlucerci Y., Dogan B. S. U., et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
, vol.92, no.12, pp.1021-1027, 2014 (SCI-Expanded, Scopus)
2013
201328. Control of human vascular tone by prostanoids derived from perivascular adipose tissue
Ozen G., Topal G., Gomez I., Ghorreshi A., Boukais K., Benyahia C., et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS
, vol.107, pp.13-17, 2013 (SCI-Expanded, Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2021
20211. İstanbul Üniversitesi Eczacılık Fakültesi Öğrencilerinin Klinik Ortam Eğitimleri
ALP YILDIRIM F. İ., ÇARÇAK YILMAZ N., PALA KARA Z., KALELİ DURMAN D., ÖZEN YORGANCIGİL G., ÖZTÜRK SEYHAN N., et al.
III. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi (ECZAKDER), Çevrimiçi, Turkey, 17 - 19 November 2021, (Summary Text)
2021
20212. Association between synovial fluid prastanoid levels and cartilage thickness in knee osteoarthritis
Çelik Z., Özen Yorgancıgil G., Şen E. İ., Topal Tanyılmaz G., Şahbaz T., Dıraçoğlu D.
26th National and 1st International Pharmacology Congress, İstanbul, İstanbul, Turkey, 04 November 2021, pp.379, (Summary Text)
2020
20203. The Investigation of Ep3 Receptor Isoforms in Human Coronary Artery and Perivascular Adipose Tissue
ÖZEN YORGANCIGİL G.
4. International Congress on Nutrition, Obesity and Community Health, 24 - 25 December 2020, (Summary Text)
2020
20204. In vitro effects of eicosapentaenoic and docosahexaenoic acid on the vascular tone of a human saphenous vein
ÇELİK Z., DACI A., ÇELİK Z., ÖZEN YORGANCIGİL G., TESKİN Ö., DASHWOOD M., et al.
23rd ANNUAL MEETING OF THE EUROPEAN COUNCIL FOR CARDIOVASCULAR RESEARCH (ECCR), 9 - 10 October 2020, (Summary Text)
2020
20205. Omega-3 polyunsaturated fatty acids reduce vascular tone and inflammation in human saphenous vein
DACI A., ÖZEN YORGANCIGİL G., UYAR İ., CİVELEK E., ALP YILDIRIM F. İ., KALELİ DURMAN D., et al.
23rd ANNUAL MEETING OF THE EUROPEAN COUNCIL FOR CARDIOVASCULAR RESEARCH (ECCR), 9 - 10 October 2020, (Summary Text)
2019
20196. İnflamatuvar koşullarda izole koroner arter bypass greft materyallerinden salıverilen prostanoidler ve ADMA arasındaki ilişkinin incelenmesi
ÖZEN YORGANCIGİL G., TOPAL G., NOREL X.
25. Ulusal Farmakoloji Kongresi, 4 - 07 November 2019, (Summary Text)
2019
20197. Pulmonary hypertension treatments: Effect of 17β-estradiol on PGI2 pathway in human pulmonary vessels
AMGOUND Y., ABDELAZEEM H., BOUHADOUN A., MANİKPURAGE H., BENYAHİA C., ÖZEN YORGANCIGİL G., et al.
16th International Conference, Bioactive Lipids in Cancer, Inflammation and Related Diseases, 20 - 23 October 2019, (Summary Text)
2019
20198. Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group III pulmonary hypertension patients.
ÖZEN YORGANCIGİL G., BENYAHİA C., AMGOUND Y., JİGİSHA P., BOUHADOUN A., YUNG S., et al.
16th International Conference, Bioactive Lipids in Cancer, Inflammation and Related Diseases, 20 - 23 October 2019, (Summary Text)
2018
20189. Measurement of Knowledge Levels of Hypertensive Patients
KARATAŞ KOÇBERBER E., ÖZEN G., Bilgin O., UYDEŞ DOĞAN B. S.
47TH ESCP Symposium on Clinical Pharmacy, Belfast, United Kingdom, 24 - 26 October 2018, (Full Text)
2018
201810. Investigation of PGE2-MMP cross-talk in human vascular preparations, their attached PVAT and plasma in obese and non-obese patients
ÖZEN G., Boumiza S., DESCHILDRE C., TOPAL TANYILMAZ G., LONGROIS D., JAKOBSSON P., et al.
7th European Workshop Lipid Mediators, Brüksel, Belgium, 12 - 14 September 2018, pp.35, (Summary Text)
2016
201611. İstanbul Üniversitesi Eczacılık Fakültesi Farmakoloji Anabilim Dalının Hasta Odaklı Lisans Eğitim Programı
ALP YILDIRIM F. İ., OKYAR A., Topal Tanyılmaz G., KALELİ DURMAN D., PALA KARA Z., ÇARÇAK YILMAZ N., et al.
II. Ulusal Eczacılık eğitimi ve Akreditasyon Kongresi, Eskişehir, Turkey, 10 - 11 May 2016, pp.24, (Summary Text)
2016
201612. İstanbul Üniversitesi Eczacılık Fakültesi Farmakoloji Anabilim Dalı’nın yürüttüğü Hasta Odaklı Eğitimin Öğrenci Geri Bildirimleri ile Değerlendirilmesi
ALP YILDIRIM F. İ., OKYAR A., Topal Tanyılmaz G., KALELİ DURMAN D., PALA KARA Z., ÇARÇAK YILMAZ N., et al.
II. Ulusal Eczacılık eğitimi ve Akreditasyon Kongresi, Eskişehir, Turkey, 10 - 11 May 2016, pp.23, (Summary Text)
2016
201613. Involvement of PGE2, regulating MMP-1 and MMP-2 in endothelial dysfunction among obese women
Boumiza S., Chahed K., Dimassi S., JACOB M., ÖZEN G., Tabka T., et al.
6th European Workshop Lipid Mediators, Frankfurt, Germany, 26 - 30 September 2016, pp.70, (Summary Text)
2016
201614. The effect of PVAT on vascular tone regulation of human coronary vessels: Role of H2S and PGE2
ÖZEN G., GOMEZ I., KOTELEVETS L., CHASTRE E., DESCHILDRE C., BOUBAYA L., et al.
7th European Congress of Pharmacology, İstanbul, Turkey, 26 - 30 June 2016, pp.131, (Summary Text)
2015
201515. Pulmoner arterlerin in vitro gevşeme cevapları prekontraksiyon için kullanılan spazmojen ajanlara yüksek oranda bağımlıdır
BENYAHIA C., ÖZEN G., ORIE N., LEDWOZYW A., LOUEDEC L., LI F., et al.
Türk Farmakoloji Derneği 23. Ulusal Farmakoloji Kongresi, Ankara, Turkey, 7 - 10 September 2015, pp.95, (Summary Text)
2014
201416. Human vascular wall remodelling by MMP is inversely regulated by PGE2 and H2S in aorta aneurysm and saphenous vein varicosity.
GOMEZ I., ÖZEN G., BOUBAYA L., GORENNE I., BENYAHIA C., ROGER T., et al.
5th European Workshop Lipid Mediators, İstanbul, Turkey, 23 - 24 October 2014, pp.33, (Summary Text)
2014
201417. Regulation of vascular tone in human grafts by PGE2 derived adipose tissue
ÖZEN G., TOPAL TANYILMAZ G., GOMEZ I., BOUBAYA L., GHORRESHI A., BOUKAIS K., et al.
When inflammation meets metabolic diseases, Paris, France, 23 May 2014, pp.16, (Summary Text)
Books
2023
20231. Nitrik Oksit Sinyal Yolağı
Çelik Z., Özen Yorgancıgil G., Topal Tanyılmaz G.
in: Türkiye Klinikleri Eczacılık Bilimleri - Özel Konular Yayın Kimliği-Kalp Yetersizliği ve Tedavisinde Yeni Hedefler, Zeliha Kerry,Tahir Yağdı, Editor, Türkiye Klinikleri Yayınevi, Ankara, pp.56-59, 2023
2022
20222. Kardiyovasküler Sistem İlaçlarının Toksik Etkileri
ÖZEN YORGANCIGİL G., TOPAL TANYILMAZ G.
in: Farmasötik Toksikoloji, Prof. Dr. Onur ERDEM, Doç. Dr. Merve BACANLI, Doç. Dr. İsmail Mert VURAL, Editor, Ankara Nobel Tıp Kitabevleri, Ankara, pp.201-236, 2022
Funded Projects
2022 - 2025
2022 - 2025İnsan kaynaklı adipoz dokularda adipokinlerin in vitro inkübasyonunun inflamatuvar mediyatörler üzerine etkileri
Project Supported by Higher Education Institutions , BAP Research Project
ÖZEN YORGANCIGİL G. (Executive), SUNAR S., DOĞRU M., TÜRKYILMAZ G., ÇELİK Z., TÜRKYILMAZ S., et al.
2021 - 2024
2021 - 2024Inflamasyonun Rezolüsyonuna Aracılık Eden Lipid Mediyatörlerin Vasküler Etkilerinin Incelenmesi
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Özen Yorgancıgil G., Teskin Ö., Uydeş Doğan B. S., Hekimoğlu E. R., Çelik Z., Eşrefoğlu M., et al.
2019 - 2024
2019 - 2024Koroner arter bypass greft materyallerinden salınan mediyatörlerin ELISA yöntemi ile ölçülmesi
Project Supported by Higher Education Institutions , BAP Other
ÖZEN YORGANCIGİL G. (Executive), UYDEŞ DOĞAN B. S., TOPAL TANYILMAZ G.
2018 - 2020
2018 - 2020Koroner arter bypass greft materyallerinde vasküler tonusun kontrolünde tromboksan reseptörünün etkisinin incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
ÖZEN YORGANCIGİL G. (Executive), TOPAL TANYILMAZ G., TÜRKYILMAZ S., ALJESRİ K., TÜRKYILMAZ G., UYDEŞ DOĞAN B. S.
2017 - 2018
2017 - 2018Role of PGE2 on MMP density in human vessels and their perivascular adipose tissue under inflammatory conditions
Project Supported by Higher Education Institutions , BAP Other
ÖZEN YORGANCIGİL G. (Executive), JAKOBSSON P., TOPAL TANYILMAZ G., NOREL X., LONGROİS D., DESCHİLDRE C., et al.
2014 - 2016
2014 - 2016Vasküler homeostaz üzerine perivasküler adipoz dokunun fizyolojik ve patofizyolojik etkisinin incelenmesi
Project Supported by Higher Education Institutions , BAP PhD
TOPAL TANYILMAZ G. (Executive), ÖZEN YORGANCIGİL G.
2013 - 2015
2013 - 2015Interactions entre prostanoides et les inhibiteurs de PDE-5 utilises lors d’hypertension pulmonaire et de dysfonction erectile
Other International Funding Programs
Özen Yorgancıgil G., Ould Yahıa C., Senbel A.(Executive), Norel X.(Executive)
2012 - 2015
2012 - 2015Vasküler tonusun düzenlenmesinde perivasküler adipoz dokuların önemi: prostanoidlerin rolü
Project Supported by Higher Education Institutions , BAP Research Project
Özen Yorgancıgil G., Uydeş Doğan B. S., Longroıs D., Teskin Ö., Ghorreshı A., Kanyinda L., et al.
2012 - 2013
2012 - 2013İnsan koroner bypass greft materyallerinin perivasküler adipoz dokularından salıverilen vazodilatör etkili faktörlerin ELISA yöntemiyle belirlenmesi
Project Supported by Higher Education Institutions , BAP Research Project
Özen Yorgancıgil G., Alp Yıldırım F. İ., Uydeş Doğan B. S., Teskin Ö., Topal Tanyılmaz G. (Executive)