Education Information
2014 - 2015
2014 - 2015Post Doctorate
University of Pittsburgh, School of Medicine, Children Hospital of Pittsburgh - Rangos Research Center, United States Of America
2006 - 2012
2006 - 2012Doctorate
Istanbul University, Health Sciences Institute, Genetik Anabilim Dalı, Turkey
2002 - 2006
2002 - 2006Postgraduate
Istanbul University, Health Sciences Institute, Genetik Anabilim Dalı, Turkey
1991 - 1995
1991 - 1995Undergraduate
Istanbul University, Cerrahpaşa Tıp Fakültesi, Tıbbi Biyolojik Bilimler Bölümü, Turkey
Dissertations
2012
2012Doctorate
Bifosfonat ve Statinlerin Çok Yönlü Etkisinde ROR-Alfa Transkripsiyon Faktörünün Olası Rolü
Istanbul University, Health Sciences Institute, Genetik Anabilim Dalı
2006
2006Postgraduate
Hipertrofik Kardiyomiyopati Hastalarında HOP Gen Mutasyonlarının Analizi
Istanbul University, Health Sciences Institute, Genetik Anabilim Dalı
Certificates, Courses and Trainings
2024
2024Makine Öğrenmesi
Data Analysis
Information and Communication Technologies Authority
2024
2024İleri Seviye Python Programlama Dili
IT
Information and Communication Technologies Authority
2024
2024Deney Hayvanları Kullanım Sertifikası
Vocational Course
Istanbul University- Local Ethics Committee on Animal Experimentation
2023
2023Eğiticinin Eğitimi
Education Management and Planning
İstanbul Üniversitesi
2021
2021Dismorfoloji Kursu
Vocational Course
Society of Medical Genetics
2019
2019Brain Malformations: A Roadmap for Future Phentyping and Research
Health&Medicine
Weizmann Institute of Science
Research Areas
Medicine
Medical Biology
Medical Genetics
Life Sciences
Bioinformatics
Molecular Biology and Genetics
Genetic Disorders
Genomics
Fundamental Medical Sciences
Natural Sciences
Academic Titles / Tasks
2023 - Continues
2023 - ContinuesAssistant Professor
Istanbul University, Istanbul Medical Faculty, Division Of Medical Sciences
2015 - 2023
2015 - 2023Other
Istanbul University, Istanbul Medical Faculty, Division Of Medical Sciences
2014 - 2015
2014 - 2015Researcher
University of Pittsburgh, School of Medicine, Developmental Biology
2008 - 2014
2008 - 2014Other
Istanbul University, Istanbul Medical Faculty, Division of Medical Sciences
2006 - 2008
2006 - 2008Other
İstanbul University-Cerrahpaşa, Cerrahpasa Faculty Of Medicine, Department Of Basic Medical Sciences
2002 - 2006
2002 - 2006Other
İstanbul University-Cerrahpaşa, Cerrahpasa Faculty Of Medicine
Courses
Advising Theses
2023
2023Doctorate
Investigation of Genes Responsible for Diaphragmatic Developmental Defects with Next Generation Sequencing Technologies.
Karaman B., Güleç Ç. (Co-Advisor)
S.HEIDARGHOLIZADEH(Student)
2019
2019Expertise In Medicine
Contribution of next generation sequencing to definitive diagnosis in cases with suspected osteogenesis imperfecta in the differential diagnosis in the pre-perinatal period
Uyguner Z. O., Güleç Ç. (Co-Advisor)
L.Şentürk(Student)
2018
2018Expertise In Medicine
The contribution of Molecular Genetic Methods to the Diagnosis of Classical Galactosemia and Investigation of Genotype-Phenotype correlation
Uyguner Z. O., Güleç Ç. (Co-Advisor)
D.İrem(Student)
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024Clinical and molecular characteristics of 26 fetuses with lethal multiple congenital contractures
Turgut G. T., Altunoglu U., Gulec Ç., Sarac Sivrikoz T., Kalaycı T., Toksoy G., et al.
CLINICAL GENETICS
, vol.105, no.6, pp.596-610, 2024 (SCI-Expanded)
2024
2024Association of Antenatal Evaluations with Postmortem and Genetic Findings in the Series of Fetal Osteogenesis Imperfecta
Senturk L., Gulec Ç., Sarac Sivrikoz T., Kayserili H., Kalelioglu I. H., Avci S., et al.
FETAL DIAGNOSIS AND THERAPY
, vol.51, no.3, pp.285-299, 2024 (SCI-Expanded)
2023
2023Novel GALT variations and genetic spectrum in Turkish population with the correlation of genotype and phenotype.
Kalay I., Gulec C., Balcı M. C., Toksoy G., Gokcay G., Basaran S., et al.
Annals of human genetics
, vol.87, no.6, pp.285-294, 2023 (SCI-Expanded)
2023
2023Gene Teams are on the Field: Evaluation of Variants in Gene-Networks Using High Dimensional Modelling
Tuna S., Gulec C., YÜCESAN E., ÇIRAKOĞLU A., Arguden Y. T.
IEEE/ACM Transactions on Computational Biology and Bioinformatics
, vol.20, no.5, pp.2959-2969, 2023 (SCI-Expanded)
2023
2023A novel RNPC3 gene variant expands the phenotype in patients with congenital hypopituitarism and neuropathy
Abali Z. Y., Ili E. G., Baş F., Ozkan M. U., Güleç Ç., Toksoy G., et al.
HORMONE RESEARCH IN PAEDIATRICS
, 2023 (SCI-Expanded)
2023
2023In Vitro investigation of insulin-like growth factor-i and mechano-growth factor on proliferation of neural stem cells in high glucose environment
Gurbuz T. A., GÜLEÇ Ç., Toprak F., Toprak S., SÖZER TOKDEMİR S.
NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY
, vol.40, no.1, pp.27-36, 2023 (SCI-Expanded)
2023
2023Clinical and bi-genomic DNA findings of patients suspected to have mitochondrial diseases
GEDİKBAŞI A., TOKSOY G., KARACA M., GÜLEÇ Ç., BALCI M. C., Gunes D., et al.
FRONTIERS IN GENETICS
, vol.14, 2023 (SCI-Expanded)
2022
2022Evaluation of Genetic Etiology in Children Born Small for Gestational Age with Persistent Short Stature: Preliminary Results
Ozturk A. P., Aslanger A., Ozturan E. K., Konur E. N., Gulec C., Karaman V., et al.
HORMONE RESEARCH IN PAEDIATRICS
, no.SUPPL 2, pp.313, 2022 (SCI-Expanded)
2022
2022Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.
Mead T. J., Martin D. R., Wang L. W., Cain S. A., Gulec Ç., Cahill E., et al.
eLife
, vol.11, 2022 (SCI-Expanded)
2022
2022Functional loss of ubiquitin-specific protease 14 may lead to a novel distal arthrogryposis phenotype.
Turgut G. T., Altunoglu U., Sivrikoz T. S., Toksoy G., Kalayci T., Avci S., et al.
Clinical genetics
, vol.101, no.4, pp.421-428, 2022 (SCI-Expanded)
2022
2022Antenatal diagnostic dilemma in a pseudodominant pedigree with lamin-B receptor (LBR)-related regressive spondylometaphyseal dysplasia
Turgut G. T., Güleç Ç., Saraç Sivrikoz T., Kale H., Karaman B., Nishimura G., et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
, vol.188, no.1, pp.253-258, 2022 (SCI-Expanded)
2021
2021A novel PSEN2 p.Ser175Phe variant in a family with Alzheimer's disease
Guven G., Samancı B., Güleç Ç., Hanagasi H., Gürvit İ. H., Gokalp E. E., et al.
NEUROLOGICAL SCIENCES
, vol.42, no.6, pp.2497-2504, 2021 (SCI-Expanded)
2021
2021ROR-Alpha May Indirectly Regulate Insulin Resistance Related Lipid Metabolism Genes Through miR-19a-3p And miR-26a-5p in Simvastatin Treatment
Coban N., Gulec C.
METABOLISM-CLINICAL AND EXPERIMENTAL
, vol.116, pp.89, 2021 (SCI-Expanded)
2020
2020LEF1 Induces DHRS2 Gene Expression in Human Acute Leukemia Jurkat T-Cells
Sırma E., Emrence Z., Abacı N., Sariman M., Salman B., Ekmekci C., et al.
Turkish Journal of Hematology
, vol.37, no.4, pp.226-233, 2020 (SCI-Expanded)
2020
2020Is the effect of rosuvastatin on ABCA1 transporter level direct or indirect?
Coban N., Gulec C.
INTERNATIONAL JOURNAL OF CARDIOLOGY
, vol.300, pp.214-216, 2020 (SCI-Expanded)
2019
2019A patient with early-onset Alzheimer's disease with a novel PSEN1 p.Leu424Pro mutation
Guven G., Erginel-Unaltuna N., Samanci B., Gulec C., Hanagasi H. A., Bilgic B.
NEUROBIOLOGY OF AGING
, vol.84, 2019 (SCI-Expanded)
2019
2019Peripheral GRN mRNA and Serum Progranulin Levels as a Potential Indicator for Both the Presence of Splice Site Mutations and Individuals at Risk for Frontotemporal Dementia
Guven G., Bilgic B., Tufekcioglu Z., Unaltuna N., Hanagasi H. A., Gurvit H., et al.
JOURNAL OF ALZHEIMERS DISEASE
, vol.67, no.1, pp.159-167, 2019 (SCI-Expanded)
2018
2018Precocious or early puberty in patients with combined pituitary hormone deficiency due to POU1F1 gene mutation: case report and review of possible mechanisms.
Bas F., Abali Z. Y., Toksoy G., Poyrazoglu S., Bundak R., Gulec Ç., et al.
Hormones (Athens, Greece)
, vol.17, no.4, pp.581-588, 2018 (SCI-Expanded)
2018
2018Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
Prins B., Mead T., Brody J., Sveinbjornsson G., Ntalla I., Bihlmeyer N., et al.
Genome biology
, vol.19, pp.87, 2018 (SCI-Expanded)
2017
2017Role of simvastatin and ROR alpha activity in the macrophage apoptotic pathway
Coban N., Gulec Ç., Selcuk B. O., Erginel-Unaltuna N.
ANATOLIAN JOURNAL OF CARDIOLOGY
, vol.17, no.5, pp.362-366, 2017 (SCI-Expanded)
2017
2017Identification of potential target genes of ROR-alpha in THP1 and HUVEC cell lines.
Gulec C., Coban N., Ozsait-Selcuk B. Ş., Sirma-Ekmekci S., Yildirim O., Erginel-Unaltuna N.
Experimental cell research
, vol.353, pp.6-15, 2017 (SCI-Expanded)
2017
2017CYP19A1, MIF and ABCA1 genes are targets of the ROR alpha in monocyte and endothelial cells
Coban N., Gulec Ç., Ozsait-Selcuk B., Erginel-Unaltuna N.
CELL BIOLOGY INTERNATIONAL
, vol.41, no.2, pp.163-176, 2017 (SCI-Expanded)
2016
2016Low dose monoethyl phthalate (MEP) exposure triggers proliferation by activating PDX-1 at 1.1B4 human pancreatic beta cells
Guven C., Dal F., Ahbab M. A., Taskin E., AHBAB S., Cinar S., et al.
FOOD AND CHEMICAL TOXICOLOGY
, vol.93, pp.41-50, 2016 (SCI-Expanded)
2015
2015High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells.
Numata M., Yener M. D., Ekmekci S., Aydin M., Grosveld G., Cardone M., et al.
Leukemia research
, vol.39, pp.906-12, 2015 (SCI-Expanded)
2014
2014Association between non-coding polymorphisms of HOPX gene and syncope in hypertrophic cardiomyopathy
Gulec C., Abaci N., Bayrak F., BAYRAK E. K., KAHVECI G., Guven C., et al.
ANATOLIAN JOURNAL OF CARDIOLOGY
, vol.14, no.7, pp.617-624, 2014 (SCI-Expanded)
2014
2014Gender specific association of ABCA1 gene R219K variant in coronary disease risk through interactions with serum triglyceride elevation in Turkish adults
Coban N., Onat A., Bayrak E. K., Gulec Ç., Can G., Unaltuna N.
ANATOLIAN JOURNAL OF CARDIOLOGY
, vol.14, no.1, pp.18-25, 2014 (SCI-Expanded)
2013
2013The relationship between endothelial nitric oxide synthase 4a/4b gene polymorphism and premature coronary artery disease
Ekmekci A., Ozcan K. S., Gungor B., Abaci N., Osmonov D., Zencirci A., et al.
ACTA CARDIOLOGICA
, vol.68, no.5, pp.464-468, 2013 (SCI-Expanded)
2013
2013The relationship between coronary artery ectasia and eNOS intron 4a/b gene polymorphisms.
EKMEKCI A., OZCAN K. S., Abaci N., GUNGOR B., OSMONOV D., TOSU R., et al.
Acta cardiologica
, vol.68, no.1, pp.19-22, 2013 (SCI-Expanded)
2012
2012SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.
Ekmekci S. S., Ekmekci C. G., Kandilci A., Gulec Ç., Akbiyik M., Emrence Z., et al.
Tumori
, vol.98, no.2, pp.252-6, 2012 (SCI-Expanded)
2011
2011HYPOXIA INDUCES ERYTHROPOIETIN RECEPTOR EXPRESSION ON K562 CELL LINE
Abaci N., Cosan F., Gulec Ç., Azakli H., Emrence Z., Sirma-Ekmekci S., et al.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
, vol.25, no.3, pp.2508-2512, 2011 (SCI-Expanded)
2011
2011Sequence variations of NKX2-5 and HAND1 genes in patients with atrial isomerism.
Hatemi A. C., Gulec Ç., Cine N., Vural B., Hatirnaz O., Sayitoglu M., et al.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
, vol.11, no.4, pp.319-28, 2011 (SCI-Expanded)
2010
2010The variations of BOP gene in hypertrophic cardiomyopathy.
Abaci N., Gulec Ç., Bayrak F., Komurcu-Bayrak E., KAHVECI G., Erginel-Unaltuna N.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
, vol.10, no.4, pp.303-9, 2010 (SCI-Expanded)
Articles Published in Other Journals
2024
2024HETEROPLASMY-ASSOCIATED MITOCHONDRIAL DNA VARIANTS IN HUMAN BLOOD AND SKELETAL MUSCLE SAMPLES
Güleç Ç., Gedikbaşı A., Sahin G., Toksoy G., Duramaz A., Uyguner Z. O.
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
, 2024 (ESCI)
2023
2023m6A İLE İLİŞKİLİ VARYANTLARIN SIKLIĞI, ÖRTÜŞTÜĞÜ G-KUADRUPLEKS YAPISININ TERMODİNAMİK KARARLILIĞI İLE DEĞİŞEBİLİR
GÜLEÇ Ç.
Sabiad , vol.6, no.3, pp.219-228, 2023 (Peer-Reviewed Journal)
2023
2023JAG1 MUTATION SPECTRUM IN CASES WITH ALAGILLE SYNDROME FROM TURKIYE
Aslanger A. D., Yildirim B. T., Kalayci T., Şentürk L., Avci Ş., Altunoğlu U., et al.
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
, vol.86, no.4, pp.327-335, 2023 (ESCI)
2023
2023Clinical and Molecular Findings of Nine Cases with Tay- Sachs Disease From Turkiye
ASLANGER A. D., GÜLEÇ Ç., KALAYCI T., Sengenc E., Avci S., Altunoglu U., et al.
MEDICAL JOURNAL OF BAKIRKOY
, vol.19, no.2, pp.222-228, 2023 (ESCI)
2022
2022CLINICAL AND MOLECULAR RESULTS OF SIX CASES WITH ROBERTS SYNDROME: REVIEW OF CASES FROM TURKIYE
Aslanger A. D., Kalaycı T., Konur E. N., Güleç Ç., Avcı Ş., Altunoğlu U., et al.
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
, vol.85, no.4, pp.501-510, 2022 (Scopus)
2022
2022GJB2-RELATED NON-SYNDROMIC HEARING LOSS VARIANTS' SPECTRUM AND THEIR FREQUENCY IN TURKISH POPULATION
Gulec C., Aslanger A. D., Karaman V., Wollnik B., Tepgec F., Karabey H. K., et al.
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
, vol.85, pp.162-169, 2022 (ESCI)
2021
2021EXPRESSION OF SELECTED miRNAs IN CIRCULATING BLOOD OF EARLY AND LATE-ONSET ALZHEIMER DISEASE PATIENTS
guven g., Lohmann E., Gulec C., bilgic b., ÖZER TOPALOĞLU E., Hanagasi H., et al.
İstanbul Tıp Fakültesi Dergisi
, vol.84, no.2, pp.165-174, 2021 (ESCI)
2018
2018Investigation of miR-155 and miR-758 Expression Levels in Peripheral Blood of Alzheimer’s Disease Patients
ÖZER E., GÜVEN Z. G., LOHMANN E., GÜLEÇ Ç., ÜNALTUNA N.
EXPERIMED , vol.2, no.8, pp.58-61, 2018 (Peer-Reviewed Journal)
2018
2018Alzheimer Hastalarının Periferik Kanlarında miR155 ve miR-758 Anlatım Düzeylerinin İncelenmesi
Özer E., GUVEN G., LOHMANN E., GÜLEÇ Ç., ÜNALTUNA N.
Experimed , vol.8, no.2, pp.1-3, 2018 (Peer-Reviewed Journal)
2016
201615 Yıllık Huntington Hastalığı Genetik Test Sonuçları ve Literatürdeki HH Test Kılavuzları
BAYRAK A. E., PODA M., GÜVEN Z. G., GEYİK F., ÇOBAN N., GÜLEÇ Ç., et al.
Deneysel Tıp Araştırma Enstitüsü Dergisi , vol.4, no.10, pp.10-16, 2016 (Peer-Reviewed Journal)
2015
201515 Yıllık Huntington Hastalığının Genetik Test Sonuçları ve Literatürdeki HH Test Klavuzları
KOMURCU-BAYRAK E., PODA M., GUCLU-GEYIK F., Güven G., ÇOBAN N., GULEC C., et al.
deneysel tıp araştırma enstitüsü dergisi , vol.5, no.10, pp.10-16, 2015 (Peer-Reviewed Journal)
2015
2015Determination of Relationship between Infection and Serum Levels of Prohepcidin in Pediatric Patients before and after Bone Marrow Transplantation
Goker B., Akbiyik M., GÖNÜL O., Gulec C., Anak S.
JOURNAL OF PEDIATRIC BIOCHEMISTRY
, vol.5, no.3, pp.94-97, 2015 (ESCI)
2013
2013Kromozom İmmunopresipitasyon Metodu (ChIP Dizileme) ile Transkripsiyon Faktörü Bağlanma Bölgelerinin Saptanması.
SIRMA EKMEKCİ S., ABACI N., GÜLEÇ Ç., ÜSTEK D.
Deneysel Tıp Dergisi , vol.3, no.6, pp.1-6, 2013 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2024
2024Step-by-Step Genetic Insight into a Case of Growth Retardation (POSTER ID P13.067.A)
Tekin A., Toksoy G., Kına B. G., Karaman B., Özsait Selçuk B. Ş., Güleç Ç., et al.
European Society of Human Genetics Congress 2024, Berlin, Germany, 01 June 2024
2023
2023Undiagnosed arthrogryposis: further expanding the molecular and phenotypic spectrum
Turgut G. T., Altunoğlu U., Saraç Sivrikoz T., Kalaycı T., Toksoy G., Avcı Ş., et al.
European Human Genetics Conference, Glasgow, England, 10 - 13 June 2023, vol.31, pp.101
2023
2023Nadir Bir Antite Ghosal Hematodiafizyel Displazi Tanılı Olgu
Hacer Demirbilek Ö., Aslanger A. D., Güleç Ç., Şahin Ş., Ağırbaşlı D., Kalaycı Yiğin A., et al.
Ulusal HematoOnkoGenetik Kongresi, Gazimagusa, Cyprus (Kktc), 4 - 07 May 2023, pp.108
2022
2022Evaluation of Genetic Etiology in Children Born Small for Gestational Age with Persistent Short Stature
ÖZTÜRK A. P., ASLANGER A. D., KARAKILIÇ ÖZTURAN E., KONUR E. N., GÜLEÇ Ç., KARAMAN V., et al.
60th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), Roma, Italy, 15 - 17 September 2022, pp.313
2022
2022Türkiye’Deki Fenilketonüri ve Hafif Hiperfenilalaninemi Popülasyonunda PahGeninin Mutasyon Spektrumu
Karaca M., Aslanger A. D., Güleç Ç., Gedikbaşı A.
15. Ulusal Tıbbi Genetik Kongresi, Muğla, Turkey, 9 - 13 November 2022, pp.75
2022
2022Osteogenezis Imperfekta Tanılı 15 Olgunun Moleküler Sonuçları
Hacer Ö., Aslanger A. D., Kalaycı T., Güleç Ç., Demir K., Toksoy G., et al.
15. Ulusal Tıbbi Genetik Kongresi, Muğla, Turkey, 09 November 2022, pp.149
2022
2022Fetal Dönemde Kontraktürler Ile Seyreden Fenotiplerin Moleküler Tanısında Tüm Ekzom Dizileme Analizinin Katkısı
Turgut G. T., Altunoğlu U., Güleç Ç., Kalaycı T., Saraç Sivrikoz T., Toksoy G., et al.
15.ULUSLARARASI KATILIMLI, ULUSAL TIBBİ GENETİK KONGRESİ, Muğla, Turkey, 9 - 13 November 2022, pp.85
2022
2022Kurum-Içi “In-House” Genetik Veritabanında Acmg Tarafından Önerilen Taşıyıcılık Taraması Genlerinin ve Raporlanması Önerilen Ikincil Bulguların Incelenmesi
DURMAZ D., GÜLEÇ Ç., KARAMAN V., TOKSOY G., YEŞİL SAYIN G.
15. Ulusal Tıbbi Genetik Kongresi, Muğla, Turkey, 9 - 13 November 2022, pp.117
2022
2022Diagnostic Usefulness of Whole Exome Sequence Analysis in cases with suspected mitochondrial disease: Single center experience
Gedikbaşı A., Balcı M. C., Karaca M., Toksoy G., Güleç Ç., Selamioğlu A., et al.
XVI. Uluslararası Katılımlı Metabolik Hastalıklar ve Beslenme Kongresi, Hatay, Turkey, 28 May - 01 June 2022, pp.144-146
2021
2021Diagnostic Utility of Whole Exome Sequencing in patients with suspected mitochondrial disease: the single center experience in Turkish population
Gedikbaşı A., Toksoy G., Karaca M., Balcı M. C., Güleç Ç., Selamioğlu A., et al.
International Congress on Inborn Errors in Metabolism (ICIEM), Sydney, Australia, 19 - 24 November 2021, pp.1-3
2021
2021VARIANTS IN THE 3 ' UNTRANSLATED REGION OF CARDIOVASCULAR-DISEASE RELATED GENES MAY BE INVOLVED IN TYPE 2 DIABETES MELLITUS THROUGH AFFECTING MIRNA BINDING SITES
Çoban N., Güleç Ç., Erkan A. F.
89th European Atherosclerosis Society Virtual Congress,, 30 May - 02 June 2021, vol.331, pp.45
2020
2020Sebebi Açıklanamayan Tekrarlayan Gebelik Kaybı ve Tekrarlayan İmplantasyon Defekti Olgularında Etiyolojinin Açıklanmasına Yönelik Yeni Yolaklar ve Genler
Berkay E., TOKSOY G., GÜLEÇ Ç., UYGUNER Z. O., BAŞARAN S.
14. ULUSAL TIBBİ GENETİK KONGRESİ, ONLINE, Turkey, 20 - 22 November 2020, no.1, pp.10
2020
2020Mitokondriyal Hastalıklara Bütünsel Yaklaşım: Beş Aile Örneği
GEDİKBAŞI A., TOKSOY G., KARACA M., BALCI M. C., GÜLEÇ Ç., GÜNEŞ S., et al.
14. ULUSAL TIBBİ GENETİK KONGRESİ, ONLINE, Turkey, 20 - 22 November 2020, vol.31, pp.45
2019
2019Pre-perinatal dönemde ayırıcı tanıda osteogenezis imperfekta düşünülen olgularda yeni nesil dizilemenin kesin tanıya katkısı
Şentürk L., Altunoğlu U., Güleç Ç., Toksoy G., Tüysüz B., Uludağ Alkaya D., et al.
4. Ulusal Çocuk Genetik Kongresi, Ankara, Turkey, 25 - 27 September 2019, pp.28
2019
2019CORONARY ARTERY DISEASE RELATED MIR-19A AND MIR-26A ARE SENSITIVE TO SIMVASTATIN AND ROR-ALPHA LIGANDS IN MACROPHAGE CELLS
Coban N., Gulec Ç., Ozuynuk A. S., Erginel-Unaltuna N., Erkan A. F.
87th Congress of the European-Atherosclerosis-Society (EAS), Maastricht, Netherlands, 26 - 29 May 2019, vol.287
2019
2019Evaluation of the novel variants found incidentally during diagnostic process in terms of N6-methyladenosine (m6A) modification
Güleç Ç.
13th Balkan Congress of Human Genetics, Edirne, Turkey, 17 - 20 April 2019, no.62, pp.98
2019
2019Interpretation of m.3243A>G in mtDNA in Clinical Expressivity Versus Tissue Heteroplasmy Ratios with Text Mining Analysis
Şahin G., Güleç Ç., Başaran S., Uyguner Z. O.
13th Balkan Congress of Human Genetics, Edirne, Turkey, 17 - 20 April 2019, pp.42
2018
2018In silico Analysis of 5'UTR-Located Variants Creating uORF and Their Potential Patogenity-Related Features
Güleç Ç.
13. Uluslararası Katılımlı Ulusal Tıbbi Genetik Kongresi, Antalya, Turkey, 7 - 11 November 2018, pp.32
2018
2018Clinical and Molecular Characterization of Stuve-Wiedmann Syndrome in Six Cases
Şentürk L., Güleç Ç., Kayserili Karabay H., Kalaycı T., Uyguner Z. O., Altunoğlu U.
13. Uluslarası Katılımlı Ulusal Tıbbi Genetik Kongresi, Antalya, Turkey, 7 - 11 November 2018, pp.123
2018
20183M Sendromlu iki oılguda CUL7 geninde saptanan üç yeni varyant
Güleç Ç., Altunoğlu U., Gedikbaşı A., Avcı Ş., Toksoy G., Uyguner Z. O., et al.
13. “Uluslararası Katılımlı” Ulusal Tıbbi Genetik Kongresi., Antalya, Turkey, 7 - 11 November 2018, vol.1, no.1, pp.272
2018
2018GALT mutation spectrum including four novel alterations in Turkish Cases With Galactosemia
Kalay İ., Balcı M. C., Güleç Ç., Avcı Ş., Toksoy G., Gökçay G. F., et al.
Erciyes Medical Genetics Days 2018, Kayseri, Turkey, 7 - 10 March 2018, vol.1, no.1, pp.46
2017
2017DNA Isolation and Preparation of Crab (Decapoda, Crustacea) Specimens For Next Generation Sequencing
PAÇAL F., ALTINSAÇLI S., ABACI N., SIRMA EKMEKCİ S., GÜLEÇ Ç., Odabaşı D. A., et al.
3rd INTERNATIONAL CONGRESS ON ZOOLOGY AND TECHNOLOGY, Afyon, Turkey, 12 - 15 July 2017, pp.47
2017
2017Geç ve erken başlangıçlı Alzheimer hastalığında rol oynayan miRNAların incelenmesi
Güven Z. G., Lohmann E., Hanağası H. A., Güleç Ç., Özer E., Ünaltuna N.
7.Ulusal Alzheimer Kongresi, Konya, Turkey, 20 - 23 April 2017, pp.1
2016
2016Expression of inflammation-related miRNAs and their selected target genes in peripheral blood mononuclear cells of early and late onset Alzheimer disease patients
GÜVEN Z. G., Lohmann E., HANAĞASI H. A., GÜLEÇ Ç., ÜNALTUNA N.
European Human Genetics Conference 2016, Barselona, Spain, 21 - 24 May 2016, vol.24E, pp.180
2014
2014Simvastatin affects ABCA1 expression and cholesterol efflux in THP-1 macrophages by a ROR-Alpha-dependent pathway.
ÇOBAN N., Güleç Ç., Özsait B., ERGINEL-UNALTUNA N.
European Human Genetics Conference, Milan, Italy, 31 May - 03 June 2014, pp.102
2013
2013p53’ün posttranslasyonel regülatörü olan HEP27’nin ekspresyonu LEF1 tarafından kontrol edilmektedir
SIRMA EKMEKCİ S., ABACI N., GÜLEÇ Ç., EMRENCE Z., Ekmekci C. G., ÜSTEK D.
XII. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, Aydın, Turkey, 27 - 30 October 2013, pp.361
2013
2013Inhibitory Effect of SR1001 on ROR-Alpha Activity Requires Intracellular Cholesterol
GÜLEÇ Ç., Çoban N., Özsait B., Sirma-Ekmekçi S., Erginel-Ünaltuna N.
European Human Genetics Conference, Paris, France, 8 - 11 July 2013, pp.461
2010
2010Tekharf Çalışmasında Metabolik Sendrom Gelişimini Etkileyen Genetik Risk Faktörlerinin Belirlenmesi
Ünaltuna N., Bayrak A. E., Çoban N., Onat A., Güleç Ç., Poda M., et al.
26. Ulusal Kardiyoloji Kongresi, İstanbul, Turkey, 21 - 24 October 2010, pp.22
2010
2010Genetic variation in the mcyB gene of Microcystis strains of Küçükçekmece Lagoon
SEVER KAYA D., GÜLEÇ Ç., ÜSTEK D., Akçaalan Albay R., ALBAY M.
8th International Conference on Toxic Cyanobacteria, İstanbul, Turkey, 29 August - 04 September 2010, pp.1
2008
2008Genotyping of Helicobacter pylori strains from south Turkey
Uzun S., Aslan A., Temiz M., Hakverdi S., Özcan B., Güleç Ç., et al.
Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Greece, 28 June - 03 July 2008, vol.275, pp.277
2004
2004Kantitatif PCR Yöntemi ile Kalbe Özgü cDNA Klonlarının Farklı Dokulardaki Ekspresyon Düzeylerinin Analizi
Abacı N., Güleç Ç., Bayrak A. E., Ünaltuna N.
VI. Ulusal Prenatal Tanı ve Tıbbi Genetik Kongresi, Antalya, Turkey, 21 - 24 April 2004, pp.30
Books & Book Chapters
2023
2023RNA Modifications
Güleç Ç.
in: Epigenetics, Doç. Dr. Yelda Tarkan Argüden, Editor, Türkiye Klinikleri Yayınevi, Ankara, pp.26-32, 2023
2023
2023Moleküler Tanı Yöntemler - Yeni Nesil Dizileme Yöntemleri
GÜLEÇ Ç.
in: Pediatri Pratiğinde Genetik Testlerin Seçimi ve Yorumlanması, Beyhan Tüysüz, Editor, Ankara Nobel Tıp Kitabevleri, Ankara, pp.91-101, 2023
2023
2023Moleküler Tanı Yöntemler - Polimeraz Zincir Reaksiyonu (PCR) ve Çeşitleri, DNA Dizi Analizi
GÜLEÇ Ç.
in: Pediatri Pratiğinde Genetik Testlerin Seçimi ve Yorumlanması, Beyhan Tüysüz, Editor, Ankara Nobel Tıp Kitabevleri, Ankara, pp.81-90, 2023
2023
2023İnsan Genomunun Organizasyonu
GÜLEÇ Ç., GÜVEN Z. G.
in: Pediatri Pratiğinde Genetik Testlerin Seçimi ve Yorumlanması, Beyhan Tüysüz, Editor, Ankara Nobel Tıp Kitabevleri, Ankara, pp.1-14, 2023
2020
2020Taşıyıcı Tarama Testleri
Güleç Ç., Uyguner Z. O.
in: Güncel Genetik Tabanlı Tarama Testleri, Haluk Akın, Editor, Türkiye Klinikleri Yayınevi, Ankara, pp.45-54, 2020
2017
2017Genetic Risk Factors for Coronary Heart Diseases and Metabolic Syndrome
Ünaltuna N., Bayrak A. E., Çoban N., Geyik F., Poda M., Selçuk B. Ş., et al.
in: TEKHARF 2017, Leadership to the Approach of Medicine World to Chronic Diseases, Prof. Dr. Altan Onat, Editor, Logos Yayınevi, İstanbul, pp.262-275, 2017
2015
2015TEKHARF Genetik Kanadı Koroner Kalp Hastalığı ve Metabolik Sendrom Genetik Risk Faktörleri
Ünaltuna N., Bayrak A. E., Çoban N., Geyik F., Poda M., Selçuk B. Ş., et al.
in: TEKHARF 2015 Yetişkinlerimizin Sağlığı ve Kronik Hastalıklara Tıbbın Yaklaşımına Öncülük, Altan Onat, Editor, Logos Yayınevi, İstanbul, pp.329-252, 2015
2015
2015TEKHARF genetik Kanadı: Koroner Kalp Hastalığı ve Metabolik SEndrom Genetik Risk Faktörleri
ERGINEL-UNALTUNA N., BAYRAK E. K., ÇOBAN N., GEYİK F., PODA M., Özsait B., et al.
in: TEKHARF 2015: Yetişkinlerimizin Sağlığı ve Kronik Hastalıklara Tıbbın Yaklaşımına Öncülük, Onat A, Editor, Logos Yayıncılık, İstanbul, pp.240-252, 2015
2011
2011TEKHARF 2011, Halkımızın Kusurlu Kalp Sağlığına Işık Yoluyla, Tıbba Büyük Katkı
UNALTUNA N. E., PODA M., BAYRAK A. E., OZSAIT B., GUCLU-GEYIK F., ÇOBAN N., et al.
in: TEKHARF Genetik Kanadı Koroner Kalp Hastalığı ve Metabolik Sendrom Genetik Risk Faktörleri, Onat A., Editor, Logos Yayıncılık Tic. A.Ş., İstanbul, pp.209-219, 2011
Supported Projects
2024 - Continues
2024 - ContinuesTüm ekzom dizileme metodu kullanılarak pulmoner hipertansiyon ile ilişkili varyantların belirlenmesi ve aday genlerin ekspresyon düzeylerinin incelenmesi
Project Supported by Higher Education Institutions
ÇOBAN N. (Executive), ERTUĞRUL A. S., EKİCİ B., KOÇAK A., BÜYÜKKAYA P., BİLGİN A. G., et al.
2022 - Continues
2022 - ContinuesDinamik mutasyon hastalıkları için moleküler genetik tanı kitlerinin geliştirilmesi
Project Supported by Higher Education Institutions
UYGUNER Z. O. (Executive), PARMAN F. Y., TÜYSÜZ B., KARA B., AKÇAYA N. H., YEŞİL SAYIN G., et al.
2023 - 2025
2023 - 2025Mitofusin 2 (MFN2) Geni ile İlişkili Yolakların Primer İnfertilite ve Tekrarlayan Gebelik Kayıpları Üzerine Etkisinin Araştırılması
Emergency R&D Project of Group A
(Project Abstract)
Gezik C., Özsait Selçuk B. Ş. (Executive), Toksoy G., Güleç Ç.
2019 - 2025
2019 - 2025
Nörodejeneratif ve Nöroinflamatuvar Hastalıklar Araştırma Birimi - NöroDİAB
CB Strateji ve Bütçe Başkanlığı (Kalkınma Bakanlığı) Projesi
(Project Abstract)
DENİZ G. (Executive), DURSUN E., ÜRESİN A. Y., ERGEN H. A., ABACI N., BAYRAM A., et al.
2021 - 2023
2021 - 2023Tıbbi Genetik Anabilim Dalında Değerlendirilen Olguların Retrospektif Analizi
Project Supported by Higher Education Institutions
YEŞİL SAYIN G. (Executive), GÜLEÇ Ç., ASLANGER A. D., SALMAN S. B., DURMAZ D., TOKSOY G., et al.
2018 - 2023
2018 - 2023Diyafragma Gelişim Defektlerinden Sorumlu Genlerin Yeni Nesil Dizileme Teknolojileri İle Araştırılması
Project Supported by Higher Education Institutions
(Project Abstract)
KARAMAN B. (Executive), HEİDARGHOLİZADEH S., GÜLEÇ Ç.
2019 - 2022
2019 - 2022Metabolik Sendrom hastalarında miRNA anlatım düzeylerinin incelenmesi
Project Supported by Higher Education Institutions
ÜNALTUNA N. (Executive), ÖZUYNUK A. S., GÜLEÇ Ç., KÖSEOĞLU P.
2018 - 2021
2018 - 2021Diyafragmatik Herni Olgularında Genetik Etiyolojinin Arastırılması
Project Supported by Higher Education Institutions
KARAMAN B. (Executive), HEİDARGHOLİZADEH S., TOKSOY G., BAŞARAN S., GÜLEÇ Ç., YÜKSEL A.
2019 - 2020
2019 - 2020Alzheimer hastalığı ve PSEN1 Glu318Gly varyantının ilişkisi
Project Supported by Higher Education Institutions
GÜVEN Z. G. (Executive), GÜLEÇ Ç., BİLGİÇ B., HANAĞASI H. A., ASLAN R., TÜFEKÇİOĞLU Z., et al.
2018 - 2019
2018 - 2019Preperinatal dönemde ayırıcı tanıda osteogenezis imperfekta düşünülen olgularda yeni nesil dizilemenin kesin tanıya katkısı
Project Supported by Higher Education Institutions
UYGUNER Z. O. (Executive), GÜLEÇ Ç., ŞENTÜRK L.
2018 - 2019
2018 - 2019Klasik Galaktozemide GALT Geni Mutasyon Spektrumu ve GenotipFenotip İlişkisinin Araştırılması
Project Supported by Higher Education Institutions
UYGUNER Z. O. (Executive), KALAY İ., GÜLEÇ Ç.
2015 - 2017
2015 - 2017GRN genindeki varyantların etkilerinin araştırılması
Project Supported by Higher Education Institutions
ÜNALTUNA N. (Executive), GÜLEÇ Ç., GÜRVİT İ. H., GÜVEN Z. G.
2014 - 2015
2014 - 2015Identification of New Candidate Genes Responsible for The Congenital Heart Diseases
TUBITAK Project
Güleç Ç. (Executive)
2013 - 2014
2013 - 2014Inhibitory Effect of SR1001 on ROR-Alpha Activity Requires Intracellular Cholesterol
Project Supported by Higher Education Institutions
GÜLEÇ Ç. (Executive)
Activities in Scientific Journals
2022 - Continues
2022 - ContinuesFRONTIERS IN PEDIATRICS
Assistant Editor/Section Editor
2022 - Continues
2022 - ContinuesFRONTIERS IN GENETICS
Assistant Editor/Section Editor
Memberships / Tasks in Scientific Organizations
2017 - Continues
2017 - ContinuesIstanbul Society of Pediatric Hematology Oncology
Member
2015 - Continues
2015 - ContinuesSociety of Medical Genetics
Member
2012 - Continues
2012 - ContinuesSociety of Medical Biologists
Member
2019 - 2021
2019 - 2021Society of Medical Biologists
Board Member
Scientific Refereeing
January 2023
January 2023FRONTIERS IN CARDIOVASCULAR MEDICINE
Journal Indexed in SCI-E
December 2022
December 2022JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
National Scientific Refreed Journal
October 2022
October 2022FRONTIERS IN GENETICS
Journal Indexed in SCI-E
October 2022
October 2022FRONTIERS IN GENETICS
Journal Indexed in SCI-E
June 2022
June 2022JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
National Scientific Refreed Journal
April 2022
April 2022FRONTIERS IN ONCOLOGY
Journal Indexed in SCI-E
February 2022
February 2022BMC CARDIOVASCULAR DISORDERS
SCI Journal
January 2021
January 2021BMC CARDIOVASCULAR DISORDERS
Journal Indexed in SSCI
July 2015
July 2015ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
February 2015
February 2015ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
November 2013
November 2013ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
September 2013
September 2013ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
August 2013
August 2013ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
July 2010
July 2010ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
Journal Indexed in SCI-E
Mobility Activity
2014 - 2015
2014 - 2015Post Doc
Post Doc
University of Pittsburgh, United States Of America
Awards
October 2023
October 2023Genç Araştırmacı Teşvik Ödülü 1. liği
Türk Diş Hekimleri Birliği
November 2018
November 2018In silico Analysis of 5UTR-Located uORF-Forming Variants and Their Potential Pathogenity-Related Features
Tıbbi Genetik Derneği
Congress and Symposium Activities
18 January 2024 - 20 January 2024
18 January 2024 - 20 January 2024Manipal Genetics Update VII
Attendee
Udupi-India
01 April 2019 - 01 April 2019
01 April 2019 - 01 April 201913th Balkan Congress of Human Genetics
Attendee
Edirne-Turkey
01 November 2018 - 01 November 2018
01 November 2018 - 01 November 2018Uluslararası Katılımlı XIII. Ulusal Tıbbi Genetik Kongresi
Attendee
Antalya-Turkey
01 July 2013 - 01 July 2013
01 July 2013 - 01 July 2013European Human Genetics Conference
Attendee
Paris-France
Invited Talks
February 2019
February 2019International Participated Erciyes Medical Genetics Days 2019
Conference
Erciyes Üniversitesi-Turkey
Scholarships
2014 - 2015
2014 - 20152219 Yurt Dışı Doktora Sonrası Araştırma Bursu
TUBITAK
Citations
Total Citations (WOS): 193
h-index (WOS): 8
Jury Memberships
June-2024
June 2024Post Graduate
Post Graduate - İstanbul Üniversitesi-Cerrahpaşa
May-2024
May 2024Doctoral Examination
Doctoral Examination - İstanbul Üniversitesi
March-2024
March 2024Doctorate
Doctorate - İstanbul Üniversitesi
December-2023
December 2023Doctoral Examination
Doctoral Examination - İstanbul Üniversitesi
August-2023
August 2023