Prof. ZÜHAL YAPICI OBUZ

Metrics

Publication

119

Publication (WoS)

Publication (Scopus)

Citation (WoS)

1208

H-Index (WoS)

Citation (Scopus)

1340

H-Index (Scopus)

Citation (Scholar)

H-Index (Scholar)

Project

Open Access

UN Sustainable Development Goals

Education

1999 - 2004

Post Doctorate of Medicine

Istanbul University, Istanbul Medical Faculty, Nöroloji Ad, Çocuk Nörolojisi Bd, Turkey

1989 - 1994

Expertise In Medicine

Şişli Etfal Hastanesi Nöroloji, Nöroloji, Turkey

1982 - 1988

Undergraduate

Istanbul University, Cerrahpaşa Tıp Fakültesi, Turkey

Dissertations

2004

Expertise In Medicine

Serebral Kortikal Gelişim Malformasyonları’nda Klinik ve Manyetik Rezonans Görüntüleme Özellikleri

Istanbul University, Nöroloji, Çocuk Nörolojisi

1994

Expertise In Medicine

İntraserebral Hematomlarda Akut Dönemde Prognozu Etkileyen Faktörler

--Seçiniz--, Nöroloji

Foreign Languages

B2 Upper Intermediate

English

Research Areas

Medicine

Health Sciences

Internal Medicine Sciences

Neurology

Academic Positions

2012 - Present

Professor

Istanbul University, Istanbul Medical Faculty, Dahili Bilimler

2006 - Present

Associate Professor

Istanbul University, Istanbul Medical Faculty, Dahili Bilimler

Managerial Experience

2009 - 2013

Deputy Chief Physician

İstanbul Üniversitesi

Non Academic Experience

2019 - 2019

Invited speaker for 6 months

Nöroloji Kliniği, Invited speaker for 6 months

2004 - 2005

Clinical research on TSC and MRS

Wake Forest University, Clinical research on TSC and MRS

2002 - 2003

Research on Tuberosclerosis

UT, Southwestern Medical Center, Research on Tuberosclerosis

1995 - 1997

Nöroloji uz

Gebze Devlet Hastanesi, Nöroloji uz

1993 - 1994

Clinical Research

Baylo College of Medicine, Clinical Research

1993 - 1994

Observer/Clinical research

University of Texas, Observer/Clinical research

Courses

Undergraduate

Kranial felçler

Articles

2025

1. Missense variants in PKAN: insights from a multi-patient genetic analysis

Kılıç M., Mercan S., Barut B. Ö., Demirkıran D. M., Yalçın Çakmaklı G., Akçakaya N. H., et al.

Neurogenetics , vol.26, pp.82-90, 2025 (Peer-Reviewed Journal)

2025

2. Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Uygun Ö., Özcan A., Aras F. K., Bozdemir E., Uğur İşeri S., GÜLTEKİN M., et al.

Annals of Clinical and Translational Neurology , vol.12, no.11, pp.2305-2316, 2025 (SCI-Expanded, Scopus)

2025

3. Effects of immune modulatory treatment on language and psychiatric profile in patients with electrical status epilepticus in sleep (ESES)

Emekli A. S., Dörtkol Ş. O., Savaş M., Öz F., İşcen P., Topaloğlu P., et al.

EPILEPSY & BEHAVIOR , vol.163, 2025 (SCI-Expanded)

2025

4. Factors Associated with COVID-19 Vaccination Status in Adolescents Diagnosed With Epilepsy

MUTLU C., Taşpolat E. R., Kırışman-Keleş H., Yapıcı Z., Topaloğlu P., BODUR M.

Neuropsychiatric Investigation , vol.63, no.1, 2025 (Scopus)

2025

5. QSM-Based Evidence of Brain Iron Accumulation in THAP1 Dystonia with Biallelic Mutation

Tarhan G., Kamaci I., Dusek P., ÇAPAN N., Sayman C., Turan C., et al.

Movement Disorders Clinical Practice , 2025 (SCI-Expanded, Scopus)

2024

6. Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes

Berkovic S. F., Neale B. M., Zsurka G., Zizovic M., Zimprich F., Zara F., et al.

Nature Neuroscience , vol.27, no.10, pp.1864-1879, 2024 (SCI-Expanded)

2024

7. Exome data of developmental and epileptic encephalopathy patients reveals de novo and inherited pathologic variants in epilepsy-associated genes

Çapan Ö. Y., Yapıcı Z., Özbil M., Çağlayan H. S.

Seizure , vol.116, pp.51-64, 2024 (SCI-Expanded)

2024

8. Epilepsy in dystrophinopathies: A retrospective cohort and review of the literature

Kizek Ö., Yapıcı Z., Topaloğlu P.

Epilepsy and Behavior , vol.151, 2024 (SCI-Expanded)

2024

9. Exploring shared triggers and potential etiopathogenesis between migraine and idiopathic/genetic epilepsy: Insights from a multicenter tertiary-based study

TÜRK B. G., Yeni S. N., Atalar A. Ç., Ekizoğlu E., Gök D. K., Baykan B., et al.

CLINICAL NEUROLOGY AND NEUROSURGERY , vol.237, 2024 (SCI-Expanded)

2024

10. Targeted resequencing reveals high-level mosaicism for a novel frameshift variant in WDR45 associated with beta-propeller protein-associated neurodegeneration

Susgun S., Demirel M., Yalçın Çakmaklı G., Salman B., Oguz K. K., Elibol B., et al.

International Journal of Neuroscience , vol.134, no.10, pp.1040-1045, 2024 (SCI-Expanded)

2024

11. Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models

Ha H. T., Liu S., Nguyen X. T., Vo L. K., Leong N. C., Nguyen D. T., et al.

JCI Insight , vol.9, no.8, 2024 (SCI-Expanded)

2023

12. GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture

Stevelink R., Campbell C., Chen S., Abou-Khalil B., Adesoji O. M., Afawi Z., et al.

Nature Genetics , vol.55, no.9, pp.1471-1482, 2023 (SCI-Expanded)

2023

13. Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals.

Montanucci L., Collins R. L., Niestroj L., Parthasarathy S., Xian J., Ganesan S., et al.

Nature communications , vol.14, no.1, pp.4392, 2023 (SCI-Expanded)

2023

14. Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity.

Mercan S., Akcakaya N. H., Salman B., Yapici Z., Ozbek U., Ugur Iseri S. A.

Genes & genomics , vol.45, no.1, pp.13-21, 2023 (SCI-Expanded)

2022

15. Four Turkish families with hyperekplexia: A missense mutation and the exon 1–7 deletion in the GLRA1 gene

Tezen D., Şimşir G., Çokar Ö., Demirbilek V., Başak A. N., Yapıcı Z.

Parkinsonism and Related Disorders , vol.105, pp.128-131, 2022 (SCI-Expanded)

2022

16. MYO1H is a novel candidate gene for autosomal dominant pure hereditary spastic paraplegia

Selcuk E., Kirimtay K., Temizci İmanç B., Akarsu Ş., Everest E., Baslo M. B., et al.

MOLECULAR GENETICS AND GENOMICS , vol.297, no.4, pp.1141-1150, 2022 (SCI-Expanded)

2022

17. Headache in idiopathic/genetic epilepsy: Cluster analysis in a large cohort

Atalar A. C., Türk B. G., Ekizoglu E., Gok D. K., Baykal B., Özge A., et al.

EPILEPSIA , vol.63, no.6, pp.1516-1529, 2022 (SCI-Expanded)

2022

18. Novel WDR45 frameshift variant detected by whole exome sequencing in beta-propeller protein-associated neurodegeneration disease

Susgun S., Demirel M., Yalçın Çakmaklı G., Elibol B., Iseri S. U., Yapici Z.

EUROPEAN JOURNAL OF HUMAN GENETICS , vol.30, no.SUPPL 1, pp.304-305, 2022 (SCI-Expanded)

2022

19. A case report of sudden-onset auditory neuropathy spectrum disorder associated with Brown-Vialetto-Van Laere syndrome (riboflavin transporter deficiency)

Gedik Soyuyuce O., Ayanoğlu Aksoy E., Yapici Z.

INTERNATIONAL JOURNAL OF AUDIOLOGY , vol.61, no.3, pp.258-264, 2022 (SCI-Expanded)

2022

20. Two cases with mitochondrial membrane protein-associated neurodegeneration: genetic features and long-term clinical follow-up.

Mercan S., Ugur Iseri S. A., Yigiter R., Akcakaya N. H., Saka E., Yapici Z.

Neurocase , vol.28, no.1, pp.37-41, 2022 (SCI-Expanded)

2022

21. A Patient with Glucose Transporter Type 1 Deficiency Syndrome: Paroxysmal Choreoathetosis and Cerebral Positron-Emission Tomography Findings

Yapici Z., Topaloglu P., Turkmen C., Eraksoy M., Zuberi S.

NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY , vol.39, no.1, pp.53-55, 2022 (SCI-Expanded)

2021

22. Adjunctive everolimus therapy for tuberous sclerosis complex-associated refractory seizures: Results from the postextension phase of EXIST-3

Franz D. N., Lawson J. A., Yapici Z., Ikeda H., Polster T., Nabbout R., et al.

EPILEPSIA , vol.62, no.12, pp.3029-3041, 2021 (SCI-Expanded)

2021

23. Novel Protein Biomarkers of Monoamine Metabolism Defects Correlate with Disease Severity

Trislan-Noguero A., Borras E., Molero-Luis M., Wassenberg T., Peters T., Verbeek M. M., et al.

MOVEMENT DISORDERS , vol.36, pp.690-703, 2021 (SCI-Expanded)

2021

24. Novel mutations in ATP13A2 associated with mixed neurological presentations and iron toxicity due to nonsense-mediated decay

Kirimtay K., Temizci B., GÜLTEKİN M., Yapici Z., Karabay Korkmaz A.

BRAIN RESEARCH , vol.1750, 2021 (SCI-Expanded)

2021

25. Immune alterations in subacute sclerosing panencephalitis reflect an incompetent response to eliminate the measles virus

Yentür S. P., Demirbilek V., Gurses C., Barış S., Kuru U., Ayta S., et al.

PLOS ONE , vol.16, no.1, 2021 (SCI-Expanded)

2020

26. Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and Lactate Elevation (LBSL) A Case With Long-term Follow-up

Yazici Gencdal I., DİNÇER A., Obuz O., Yapici Z.

NEUROLOGIST , vol.25, no.5, pp.144-147, 2020 (SCI-Expanded)

2020

27. Fingolimod Therapy for Pediatric Relapsing-Remitting Multiple Sclerosis: A Real-Life Study

Ilki C. D., Gunduz T., Kurtuncu M., Yapici Z., Sencer S., Eraksoy M.

TURKISH JOURNAL OF NEUROLOGY , vol.26, no.1, pp.34-38, 2020 (ESCI)

2020

28. Hypermanganesemia with Dystonia 1: A Novel Mutation and Response to Iron Supplementation

Yapici Z., Tuschl K., Eraksoy M.

MOVEMENT DISORDERS CLINICAL PRACTICE , vol.7, no.1, pp.94-96, 2020 (ESCI)

2019

29. Non-convulsive status epilepticus in two patients with tuberous sclerosis

Erdal Y., Alnak A., Oztop O., Tekturk P., Yapici Z.

CHILDS NERVOUS SYSTEM , vol.35, no.12, pp.2405-2409, 2019 (SCI-Expanded)

2019

30. Panayiotopoulos syndrome and Gastaut syndrome are distinct entities in terms of neuropsychological findings

Kalem S. A., Elmali A. D., Demirbilek V., Oktem O., YAPICI Z., SALTIK S., et al.

EPILEPSY & BEHAVIOR , 2019 (SCI-Expanded)

2019

31. Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study

Klopstock T., Tricta F., Neumayr L., Karin I., Zorzi G., Fradette C., et al.

LANCET NEUROLOGY , vol.18, no.7, pp.631-642, 2019 (SCI-Expanded)

2019

32. Genotype-phenotype Correlation in Pelizaeus Merzbacher Disease and Pelizaeus Merzbacher-like Disease

Gokcal E., Bilir B., BATTALOĞLU E., Aydin R., Yapici Z.

BEZMIALEM SCIENCE , vol.7, no.3, pp.215-220, 2019 (ESCI)

2019

33. A Novel and Mosaic WDR45 Nonsense Variant Causes Beta-Propeller Protein-Associated Neurodegeneration Identified Through Whole Exome Sequencing and X chromosome Heterozygosity Analysis.

Akcakaya N. H., Salman B., Gormez Z., Arguden Y. T., Cirakoglu A., Cakmur R., et al.

Neuromolecular medicine , vol.21, no.1, pp.54-59, 2019 (SCI-Expanded)

2019

34. Clinical and genetic spectrum of an orphan disease MPAN: a series with new variants and a novel phenotype.

Akcakaya N. H., Haryanyan G., Mercan S., Sozer N., Ali A., Tombul T., et al.

Neurologia i neurochirurgia polska , vol.53, no.6, pp.476-483, 2019 (SCI-Expanded)

2019

35. Correlation of Prechtl Qualitative Assessment of General Movement Analysis with Neurological Evaluation: The Importance of Inspection in Infants

Akcakaya N. H., Altunalan T., Dogan T. D., Yilmaz A., Yapici Z.

TURKISH JOURNAL OF NEUROLOGY , vol.25, no.2, pp.63-70, 2019 (ESCI)

2018

36. Investigation of neuronal auto-antibodies in children diagnosed with epileptic encephalopathy of unknown cause

Tekturk P., Baykan B., Erdag E., Peach S., Sezgin M., Yapici Z., et al.

BRAIN & DEVELOPMENT , vol.40, no.10, pp.909-917, 2018 (SCI-Expanded)

2018

37. Everolimus for treatment-refractory seizures in TSC: Extension of a randomized controlled trial

Franz D. N., Lawson J. A., Yapici Z., Ikeda H., Polster T., Nabbout R., et al.

NEUROLOGY-CLINICAL PRACTICE , vol.8, no.5, pp.412-420, 2018 (ESCI)

2018

38. A new splice-site mutation in SLC12A6 causing Andermann syndrome with motor neuronopathy

Akcakaya N. H., Yapici Z., Tunca C. I., Tekturk P., Akcimen F., Basak A. N.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , vol.89, no.10, pp.1123-1125, 2018 (SCI-Expanded)

2018

39. DBS in pediatric patients: institutional experience

Canaz H., Karalok I., Topcular B., Agaoglu M., Yapici Z., Aydin S.

CHILDS NERVOUS SYSTEM , vol.34, no.9, pp.1771-1776, 2018 (SCI-Expanded)

2018

40. Adjunctive everolimus for children and adolescents with treatment-refractory seizures associated with tuberous sclerosis complex: post-hoc analysis of the phase 3 EXIST-3 trial

Curatolo P., Franz D. N., Lawson J. A., Yapici Z., Ikeda H., Polster T., et al.

LANCET CHILD & ADOLESCENT HEALTH , vol.2, no.7, pp.495-504, 2018 (SCI-Expanded)

2018

41. Everolimus dosing recommendations for tuberous sclerosis complex-associated refractory seizures

Franz D. N., Lawson J. A., Yapici Z., Brandt C., Kohrman M. H., Wong M., et al.

EPILEPSIA , vol.59, no.6, pp.1188-1197, 2018 (SCI-Expanded)

2018

42. Megalencephalic leukoencephalopathy with subcortical cysts Characterization of disease variants

Hamilton E. M. C., Tekturk P., Cialdella F., van Rappard D. F., Wolf N. I., Yalcinkaya C., et al.

NEUROLOGY , vol.90, no.16, 2018 (SCI-Expanded)

2018

43. A case with CMTX1 disease showing transient ischemic-attack-like episodes

Aktan Z., Akcakaya N. H., Tekturk P., Deniz E., Koyuncu B., Yapici Z.

NEUROLOGIA I NEUROCHIRURGIA POLSKA , vol.52, no.2, pp.285-288, 2018 (SCI-Expanded)

2018

44. Cerebral Palsy and Genetics

Akcakaya N. H., Yapici Z., ÖZBEK U.

TURKISH JOURNAL OF NEUROLOGY , vol.24, no.1, pp.1-2, 2018 (ESCI)

2017

45. Pallidal Stimulation in an 11-Year-Old Boy with Treatment-Resistant Tourette Syndrome

Kilincaslan A., Aydin S., Kok B. E., Akcakaya H., Yapici Z.

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY , vol.27, no.7, pp.673-674, 2017 (SCI-Expanded)

2017

46. De novo 8p23.1 deletion in a patient with absence epilepsy

Akcakaya N. H., Capan O. Y., Schulz H., Sander T., ÇAĞLAYAN S. H., Yapici Z.

EPILEPTIC DISORDERS , vol.19, no.2, pp.217-221, 2017 (SCI-Expanded)

2017

47. Beneficial Effects of Everolimus on Autism and Attention-Deficit/Hyperactivity Disorder Symptoms in a Group of Patients with Tuberous Sclerosis Complex

Kilincaslan A., KOK B. E., Tekturk P., Yalcinkaya C., Ozkara C., Yapici Z.

Journal of Child and Adolescent Psychopharmacology , vol.27, no.4, pp.383-388, 2017 (SCI-Expanded)

2017

48. Clinical and genetic features of PKAN patients in a tertiary centre in Turkey

AKÇAKAYA N., Iseri S. A., BILIR B., BATTALOGLU E., TEKTURK P., GULTEKIN M. H., et al.

CLINICAL NEUROLOGY AND NEUROSURGERY , pp.34-42, 2017 (SCI-Expanded)

2017

49. Idiopathic Intracranial Hypertension: Diagnosis and Therapeutic Approach

Akcakaya N. H., Akcakaya M. O., Sencer A., Yapici Z.

TURKISH JOURNAL OF NEUROLOGY , vol.23, no.2, pp.43-50, 2017 (ESCI)

2017

50. EEG Findings in Patients with Rett Syndrome

Ayta S., Oge A. E., Gurses C., Yapici Z., Eraksoy M.

EPILEPSI , vol.23, no.2, pp.63-71, 2017 (ESCI)

2016

51. Atypical enterovirus encephalitis causing behavioral changes and autism-like clinical manifestations: case report

Akcakaya N. H., Tekturk P., Cagatay A., TUR E. K., Yapici Z.

ACTA NEUROLOGICA BELGICA , no.4, pp.679-681, 2016 (SCI-Expanded)

2016

52. Psychiatric Symptoms in Childhood Wilson's Disease: Case Reports

Demirkaya S. K., Yapici Z.

MEANDROS MEDICAL AND DENTAL JOURNAL , vol.17, no.3, pp.153-156, 2016 (ESCI)

2016

53. Eyelid myoclonic status epilepticus: A rare phenotype in spinal muscular atrophy with progressive myoclonic epilepsy associated with ASAH1 gene mutation

Akarsu E. O., Tekturk P., Yapici Z., Tepgec F., Uyguner Z. O., Baykan B.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY , vol.42, pp.49-51, 2016 (SCI-Expanded)

2016

54. Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study

French J. A., Lawson J. A., Yapici Z., Ikeda H., Polster T., Nobbout R., et al.

LANCET , vol.388, no.10056, pp.2153-2163, 2016 (SCI-Expanded)

2016

55. The effect of transcranial direct current stimulation on seizure frequency of patients with mesial temporal lobe epilepsy with hippocampal sclerosis

Tekturk P., Erdogan E. T., Kurt A., Vanli-yavuz E. N., Ekizoglu E., Kocagoncu E., et al.

CLINICAL NEUROLOGY AND NEUROSURGERY , vol.149, pp.27-32, 2016 (SCI-Expanded)

2016

56. **A novel gene mutation in PANK2 in a patient with severe jaw-opening dystonia**

Yapici Z., Akcakaya N. H., Tekturk P., Iseri S. A., Ozbek U.

BRAIN & DEVELOPMENT , no.8, pp.755-758, 2016 (SCI-Expanded)

2016

57. ADJUNCTIVE EVEROLIMUS THERAPY FOR THE TREATMENT OF REFRACTORY SEIZURES IN PEOPLE WITH TUBEROUS SCLEROSIS COMPLEX

De Vries P. J., FRANZ D. N., LAWSON J. A., Yapici Z., POLSTER T., NABBOUT R., et al.

JOURNAL OF INTELLECTUAL DISABILITY RESEARCH , vol.60, no.9, pp.839, 2016 (SSCI)

2016

58. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay

KIM M., SANDFORD E., GATICA D., QIU Y., LIU X., ZHENG Y., et al.

ELIFE , vol.5, 2016 (SCI-Expanded)

2016

59. A role of autophagy in spinocerebellar ataxiaRare exception or general principle?

Burmeister M., Lee J., Schulman B. A., Yapici Z., TOLUN A., Juhasz G., et al.

AUTOPHAGY , vol.12, no.7, pp.1208-1209, 2016 (SCI-Expanded)

2016

60. L-2-Hydroxyglutaric Aciduria: Report of Four Turkish Patients from the Same Family

Yalcin A. D., Tekturk P., Yapici Z.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH , vol.33, no.3, pp.494-500, 2016 (SCI-Expanded)

2015

61. A case of hyperkinetic movement disorder associated with LGI1 antibodies

Erer-Ozbek S., Yapici Z., Tuzun E., Giris M., Duran S., Taskapilioglu O., et al.

TURKISH JOURNAL OF PEDIATRICS , vol.57, no.5, pp.514-517, 2015 (SCI-Expanded)

2015

62. Abnormal Red Cell Structure and Function in Neuroacanthocytosis

CLUITMANS J. C. A., TOMELLERI C., Yapici Z., DINKLA S., BOVEE-GEURTS P., CHOKKALINGAM V., et al.

PLOS ONE , vol.10, no.5, 2015 (SCI-Expanded)

2015

63. Cerebrospinal fluid synaptic proteins as useful biomarkers in tyrosine hydroxylase deficiency

ORTEZ C., Duarte S. T., ORMAZABAL A., SERRANO M., PEREZ A., PONS R., et al.

MOLECULAR GENETICS AND METABOLISM , vol.114, no.1, pp.34-40, 2015 (SCI-Expanded)

2014

64. Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome

BURNS R., MAJCZENKO K., XU J., PENG W., Yapici Z., DOWLING J. J., et al.

NEUROLOGY , vol.83, no.23, pp.2175-2182, 2014 (SCI-Expanded)

2014

65. Granzyme B gene polymorphism associated with subacute sclerosing panencephalitis

Yentur S. P., Aydin H. N., Gurses C., Demirbilek V., KURU U., Uysal S., et al.

Neuropediatrics , vol.45, no.5, pp.309-313, 2014 (SCI-Expanded)

2013

66. Alterations of Red Cell Membrane Properties in Nneuroacanthocytosis

Siegl C., Hamminger P., Jank H., Ahting U., Bader B., Danek A., et al.

PLOS ONE , vol.8, no.10, 2013 (SCI-Expanded)

2012

67. Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32

STEFFENS M., LEU C., RUPPERT A., ZARA F., STRIANO P., ROBBIANO A., et al.

HUMAN MOLECULAR GENETICS , vol.21, no.24, pp.5359-5372, 2012 (SCI-Expanded)

2012

68. The Prevalence of Multiple Sclerosis in the North Caucasus Region of Turkey: Door-to-Door Epidemiological Field Study

Alp R., Alp S. I., Planci Y., Yapici Z., Boru U. T.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY , vol.49, no.4, pp.272-275, 2012 (SCI-Expanded)

2011

69. A case with hyperkinetic frontal lobe epilepsy presenting as a psychiatric disturbance

Elmi H., Kilincaslan A., Ozturk M., Yapici Z.

TURKISH JOURNAL OF PEDIATRICS , vol.53, no.5, pp.574-578, 2011 (SCI-Expanded)

2011

70. An association analysis at 2q36 reveals a new candidate susceptibility gene for juvenile absence epilepsy and/or absence seizures associated with generalized tonic-clonic seizures

Yalcin O., Baykan B., Agan K., Yapici Z., Yalcin D., Dizdarer G., et al.

EPILEPSIA , vol.52, no.5, pp.975-983, 2011 (SCI-Expanded)

2010

71. Use of the International Classification of Headache Disorders, Second Edition, criteria in the diagnosis of primary headache in schoolchildren: Epidemiology study from eastern Turkey

Alp R., Alp S. I., Palanci Y., Sur H., Boru U. T., Ozge A., et al.

CEPHALALGIA , vol.30, no.7, pp.868-877, 2010 (SCI-Expanded)

2010

72. An Overview of L-2-Hydroxyglutarate Dehydrogenase Gene (L2HGDH) Variants: A Genotype-Phenotype Study

Steenweg M. E., Jakobs C., Errami A., van Dooren S. J. M., Adeva Bartolome M. T., Aerssens P., et al.

HUMAN MUTATION , vol.31, no.4, pp.380-390, 2010 (SCI-Expanded)

2009

73. Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance

Dibbens L. M., Mullen S., Helbig I., Mefford H. C., Bayly M. A., Bellows S., et al.

HUMAN MOLECULAR GENETICS , vol.18, no.19, pp.3626-3631, 2009 (SCI-Expanded)

2009

74. L-2-Hydroxyglutaric Aciduria: Pattern of MR Imaging Abnormalities in 56 Patients

Steenweg M. E., Salomons G. S., Yapici Z., Uziel G., Scalais E., Zafeiriou D. I., et al.

RADIOLOGY , vol.251, no.3, pp.856-865, 2009 (SCI-Expanded)

2008

75. Devic's neuromyelitis optica: Prognostic implications of NMO IgG status in Turkish patients

Akman-Demir G., Tuzun E., Jarius S., Icoz S., Kurtuncu M., Waters P., et al.

JOURNAL OF NEUROIMMUNOLOGY , vol.203, no.2, pp.184, 2008 (SCI-Expanded)

2008

76. CD46 expression is decreased in subacute sclerosing panencephalitis patients

Yentur S. P., Gurses C., Demirbilek V., Uysal S., Yilmaz G., Yapici Z., et al.

JOURNAL OF NEUROIMMUNOLOGY , vol.203, no.2, pp.201, 2008 (SCI-Expanded)

2008

77. Paroxysmal non-kinesigenic and hypnogenic dyskinesia associated with Streptococcal infection

Senbil N., Yapici Z., Gurer Y. K. Y.

PEDIATRICS INTERNATIONAL , vol.50, no.2, pp.255-256, 2008 (SCI-Expanded)

2008

78. Incontinentia pigmenti mimicking a herpes simplex virus infection in the newborn

Okan F., Yapici Z., Bulbul A.

CHILDS NERVOUS SYSTEM , vol.24, no.1, pp.149-151, 2008 (SCI-Expanded)

2007

79. Analgesia in preterm newborns: the comparative effects of sucrose and glucose.

Okan F., Coban A., Ince Z., Yapici Z., Can G.

European journal of pediatrics , vol.166, no.10, pp.1017-24, 2007 (SCI-Expanded)

2007

80. Neurological aspects of tuberous sclerosis in relation to MRI/MR spectroscopy findings in children with epilepsy

Yapici Z., Doertcan N., Baykan B., Okan F., Dincer A., Baykal C., et al.

NEUROLOGICAL RESEARCH , vol.29, no.5, pp.449-454, 2007 (SCI-Expanded)

2007

81. High interleukin-10 production is associated with anti-acetylcholine receptor antibody production and treatment response in juvenile myasthenia gravis

YAPICI Z., Tuezuen E., ALTUNAYOGLU V., ERDOGAN A., ERAKSOY M.

INTERNATIONAL JOURNAL OF NEUROSCIENCE , vol.117, no.11, pp.1505-1512, 2007 (SCI-Expanded)

2006

82. Subacute sclerosing panencephalitis presenting with Balint's syndrome

Yapici Z.

BRAIN & DEVELOPMENT , vol.28, no.6, pp.398-400, 2006 (SCI-Expanded)

2006

83. Worster-Drought syndrome (congenital bilateral perisylvian syndrome) with posterior pituitary ectopia, pituitary hypoplasia, empty sella and panhypopituitarism: A patient report

Bas F., Darendeliler F. F., Yapıcı Z., Gökalp S., Bundak R., Sakai N., et al.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM , vol.19, no.4, pp.535-540, 2006 (SCI-Expanded)

2006

84. Subacute sclerosing panencephalitis surveillance study in Istanbul

Onal A. E., Gürses C., Direskeneli G., Yılmaz G., Demirbilek V., Yentur S. P., et al.

BRAIN & DEVELOPMENT , vol.28, no.3, pp.183-189, 2006 (SCI-Expanded)

2005

85. Alterations in cell-mediated immune response in subacute sclerosing panencephalitis.

Yendur S. P., Gurses C., Demirbilek V., Yilmaz G., Onal A., Yapici Z., et al.

Journal of neuroimmunology , vol.170, pp.179-85, 2005 (SCI-Expanded)

2005

86. Çocukluk Çağı Baş ağrılarının Sınıflandırılması ve Depresyon, Anksiyete, Benlik Saygısı Ölçeklerinin Değerlendirilmesi

KOCASOY ORHAN E., Başgül S., YAPICI Z., Ş. Üneri Ö., ERAKSOY M.

Türk Nöroloji Derneği Dergisi , no.11, pp.605-610, 2005 (Peer-Reviewed Journal)

2005

87. Elevated interleukin-12 and CXCL10 in subacute sclerosing panencephalitis

Saruhan-Direskeneli G., Gurses C., Demirbilek V., Yentur S. P., Yilmaz G., Onal E. Z., et al.

CYTOKINE , vol.32, no.2, pp.104-110, 2005 (SCI-Expanded)

Papers Presented at Peer-Reviewed Scientific Conferences

2024

1. İVİG Tedavisinin Uykuda Elektriksel Status Epileptikus Hastalarındaki İmmün Cevap ile İlişkisi.

Koral G., Soylu S., Topaloğlu P., Emekli A. S., Karaaslan Z., Yüceer Korkmaz H., et al.

13. Klinik Nöroimmünoloji Sempozyumu, Antalya, Turkey, 13 - 18 May 2024, (Unpublished)

2024

2. Mitokondriyal-Membran Proteini İlişkili Nörodejenerasyona Neden Olan C19orf12 Geni 5’UTR Varyantının İn Siliko Analizleri

Kılıç M., Salman B., Süsgün S., Yücesan E., Uğur İşeri S. A., Yapıcı Obuz Z.

1. Nörogenetik ve Nörometabolizma Kongresi, İstanbul, Turkey, 9 - 11 May 2024, (Unpublished)

2023

3. Multiple Rating Scales in 17 patients with Mitochondrial-membrane Protein Associated Neurodegeneration

SAYMAN C., ÇAPAN N., TOPALOĞLU P., UĞUR İŞERİ S. A., ÖZDEMİR S., BASLO M. B., et al.

17th Congress of the European Forum for Research in Rehabilitation, 02 November 2023, (Full Text)

2018

4. Çocukluk Yaş Başlangıçlı Demiyelinizan Hastalıklarda Klinik-demografik Özellikler Ve Anti-MOG (Myelin Oligodendrosit Glikoprotein) Antikorlarının Prognoz Üzerindeki Etkilerinin Belirlenmesi

DUMAN İLKİ C., GÜNDÜZ T., TOPALOĞLU P., YAPICI Z., KÜRTÜNCÜ M., ERAKSOY M.

54. Ulusal Nöroloji Kongresi, Turkey, 30 November - 06 December 2018, (Summary Text)

2018

5. Impact of Mutation Status on Seizure Outcomes in Patients with Tuberous Sclerosis Complex (TSC) Treated in the EXIST-3 Study

Yapici Z., Franz D., Lawson J., Ikeda H., Polster T., Nabbout R., et al.

70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los-Angeles, Chile, 21 - 27 April 2018, vol.90, (Summary Text)

2018

6. Efficacy and Safety of Everolimus Based on Prior and Concomitant Antiepileptic Drugs in Patients with Tuberous Sclerosis Complex (TSC)-Associated Treatment-Refractory Seizures: A Subanalysis of the Phase 3 EXIST-3 Study

Franz D., Lawson J., Yapici Z., Ikeda H., Polster T., Nabbout R., et al.

70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los-Angeles, Chile, 21 - 27 April 2018, vol.90, (Summary Text)

2017

7. NEDENİ BELİRLENEMEYEN EPİLEPTİK ENSEFALOPATİLERDE OTOİMMUN ANTİKORLARIN ARAŞTIRILMASI

Tektürk P., Baykal B., Erdağ E., Sezgin M., Küçükali C. İ., Yapıcı Z., et al.

53. Ulusal Nöroloji Kongresi, Antalya, Turkey, 24 - 30 November 2017, pp.13, (Summary Text)

2017

8. 32 novel pathogenic sequence variants in 253 DMD/BMD patients from Turkey

Toksoy G., Agayev A., Bagirova G., Tekçe H., YAPICI Z., KAYSERİLİ KARABEY H., et al.

. European Human Genetics Conference, May 27-30, 2017, Copenhagen, Denmark., 27 - 30 May 2017, (Summary Text)

2016

9. DİSTONİK STATUS İLE SEYREDEN SUBAKUT SKLEROZAN PANENSEFALİT OLGUSU

Sezgin M., Topaloğlu P., Taşkın A., Yapıcı Obuz Z.

52. ULUSAL NÖROLOJİ KONGRESİ , Antalya, Turkey, 25 November - 01 December 2016, pp.88-89, (Summary Text)

2016

10. Adjunctive Everolimus Therapy for the Treatment of Refractory Seizures Associated with Tuberous Sclerosis Complex: Results from a Randomized, Placebo-Controlled, Phase 3 Trial

FRENCH J. A., LAWSON J. A., Yapici Z., Polster T., NABBOUT R., CURATOLO P., et al.

141st Annual Meeting of the American-Neurological-Association, Maryland, United States Of America, 16 - 18 October 2016, vol.80, (Summary Text)

2016

11. Adjunctive everolimus therapy for the treatment of refractory seizures associated with tuberous sclerosis complex: Results from a randomized, placebo-controlled, phase 3 trial

FRENCH J., LAWSON J. A., Yapici Z., POLSTER T., NABBOUT R., CURATOLO P., et al.

68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver, Canada, 15 - 21 April 2016, vol.87, (Summary Text)

2015

12. Paroksismal ataksi ve işitme kaybı ile başvuran geç başlangıçlı Akçaağaç Şurubu İdrarı Hastalığı (MSUD) vakası.

GÜNEŞ D., KARACA M., BALCI M. C., KOZANOĞLU T., YAPICI OBUZ Z., MUTLU Ü. D., et al.

37. Pediatri Günleri ve 16. Pediatri Hemşireliği Günleri, İstanbul, Turkey, 8 - 11 April 2015, pp.215, (Summary Text)

2015

13. COMPARISON OF THE EFFECT OF TRANSCRANIAL DIRECT CURRENT STIMULATION BETWEEN FOCAL AND GENERALIZED EPILEPSY SYNDROMES

Tekturk P., Erdogan E. T., Kurt A., Yavuz E. N. V., Kocagoncu E., Aksu S., et al.

31st International Epilepsy Congress, İstanbul, Turkey, 5 - 09 September 2015, pp.203, (Summary Text)

2014

14. IFN-gamma response against measles virus peptides in subacute sclerosing panencephalitis patients

Yentur S. P., Adin-cinar S., Gurses C., Demirbilek V., BARIŞ S., Ayta S., et al.

12th International Congress of Neuroimmunology (ISNI), Mainz, Germany, 9 - 13 November 2014, vol.275, pp.212, (Summary Text)

2014

15. A case with autosomal recessive hypermanganesemia: clinical and MRI findings

Yapici Z., Tekturk P., Tuschl K., Eraksoy M., Barlas M., Ozcan H.

Joint Congress of European Neurology, İstanbul, Turkey, 31 May - 03 June 2014

2014

16. Transcranial direct current stimulation for seizure control in patients with Lennox-Gastaut syndrome

Tekturk P., Erdogan E. T., KURT A. R., Kucuk Z., AKSU S., Karamursel S., et al.

Joint Congress of European Neurology, İstanbul, Turkey, 31 May - 03 June 2014, pp.226, (Summary Text)

2014

17. Functional subsets of T Cells are altered in Subacute Sclerosing Panencephalitis Patients.

Yentür S. P., Çınar S., Barış S., Demirbilek A. V., Gürses R. C., Ayta S., et al.

2nd International Molecular Immunology and Immunogenetics Congress (MIMIC-II), Antalya, Turkey, 27 - 30 April 2014, pp.67, (Summary Text)

2012

18. IFN-g response against measles virus peptides in subacute sclerosing panencephalitis patients

Yentur S. P., Ayta S., Demirbilek V., Gurses C., Uysal S., Yapici Z., et al.

11th International Congress of Neuroimmunology (ISNI), Massachusetts, United States Of America, 4 - 08 November 2012, vol.253, pp.139, (Summary Text)

2012

19. IFN-g response against measles virus peptides in subacute sclerosing panencephalitis patients

DEMİRBİLEK A. V., YENTÜR S. P., Ayta S., GÜRSES R. C., Uysal S., YAPICI Z., et al.

11th International Congress of Neuroimmunology, Boston, United States Of America, 4 - 08 November 2012, vol.253, no.1, pp.139, (Full Text)

2012

20. A Case Of MRI Negative Neurobrucellosis With Isolated Spinal Cord Involvement

GÜNDÜZ T., TOPALOĞLU P., ERAKSOY M., YAPICI Z.

ICNC2012 (12th International Child Neurology Congress), Brisbane, Australia, 27 May - 01 June 2012, vol.54, pp.1-220, (Summary Text)

2011

21. Subakut Sklerozan Panensefalit'te SLAM (CD150).

YENTÜR S. P., DEMİRBİLEK A. V., UYSAL S., GÜRSES R. C., BARIŞ S., YAPICI Z., et al.

21. Ulusal Immünoloji Kongresi, Turkey, 06 May 2011, (Summary Text)

2010

22. Familial effects on the age of onset, initial symptoms and clinical course of multiple sclerosis

ERAKSOY M., DEMİR F. G., YAPICI Z., GÜNDÜZ T., KÜRTÜNCÜ M.

20th Meeting of the European Neurological Society, Berlin, Germany, 19 - 23 June 2010, vol.257, pp.1-246, (Summary Text)

2008

23. Headache etiology in children: a prospective study of 155 cases

Alp R., Alp S. I., Ozge A., Yapici Z.

7th International Congress on Headache in Children and Adolescents, İstanbul, Turkey, 17 - 21 May 2008, vol.28, pp.458-459, (Summary Text)

2008

24. The prevalence of headache in schoolchildren in Agri, east of Turkey

Alp R., Alp S. I., Palanci Y., Sur H., Turk U., ÖZGE A., et al.

7th International Congress on Headache in Children and Adolescents, İstanbul, Turkey, 17 - 21 May 2008, vol.28, pp.443-444, (Summary Text)

2008

25. Devic's neuromyelitis optica: An analysis of 47 patients and prognostic implications of NMO IgG status

Akman-Demir G., ERAKSOY M., TÜZÜN E., Jarius S., Icoz S., Kartuncu M., et al.

60th Annual Meeting of the American-Academy-of-Neurology, Illinois, United States Of America, 12 - 19 April 2008, vol.70, (Summary Text)

2007

26. Clinical profile in GJA12 mutations: Nine Turkish children

Yapici Z., BILIR B., Yalcinkaya C., Isoglu-Alkac U., BATTALOGLU E., Eraksoy M.

59th Annual Meeting of the American-Academy-of-Neurology, Massachusetts, United States Of America, 28 April - 05 May 2007, vol.68, (Summary Text)

2006

27. Mutation and linkage analyses of the Proteolipid Protein 1 gene in patients with Pelizaeus-Merzbacher disease

Bilir B., Yapici Z., Yalcinkaya C., Battaloglu E.

11th International Congress on Neuromuscular Diseases, İstanbul, Turkey, 2 - 07 July 2006, vol.16

2006

28. Plasma cytokine levels in juvenile myasthenia gravis: 11 patients

Yapici Z., Erdogan H. A., TÜZÜN E., Vildan A., İŞSEVER H., ERAKSOY M.

11th International Congress on Neuromuscular Diseases, İstanbul, Turkey, 2 - 07 July 2006, vol.16, (Summary Text)

2005

29. Subakut Sklerozan Panensefalit Hastalarında Staphylococcus aureus SAC ve Copolymer 1 COP 1 Uyarısı ile Gelişen Proliferasyon ve Sitokin Yanıtı

YENTÜR S. P., GÜRSES R. C., DEMİRBİLEK A. V., UYSAL S., ÇELİK G., ÇOKAR A. Ö., et al.

XVIII. Ulusal İmmünoloji Kongresi, Bursa, Bursa, Turkey, 7 - 10 September 2005, (Summary Text)

Books

2024

1. Beyinde Demir Birikimiile SeyredenNörodejeneratifHastalıklar ve PrimerAilevi BeyinKalsifikasyonları

Yapıcı Obuz Z.

in: TANIDAN TEDAVİYE NÖROGENETİK, Bülent Elibol, Editor, Türk Nöroloji Derneği , Ankara, pp.377-401, 2024

2024

2. Kortikal GelişimselMalformasyonlar ve Genetik

Erhan Şençiçek G., Çağlayan A. O., Küçümen Y., Yapıcı Obuz Z.

in: TANIDAN TEDAVİYE NÖROGENETİK, Zuhal YAPICI, Editor, Türk Nöroloji Derneği, Ankara, pp.171-256, 2024

2024

3. Nörogelişimsel Bozukluklar ve Kortikal Malformasyonlar

Yapıcı Obuz Z. (Editor)

in: TANIDAN TEDAVİYE NÖROGENETİK, Zuhal YAPICI, Editor, Türk Nöroloji Derneği, Ankara, pp.171-256, 2024

Funded Projects

2021 - 2024

Uykuda Elektriksel Status Epileptikus Hastalarının Klinik Özellikleri ve İmmünolojik ve Genetik Biyobelirteçlerin Araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

YAPICI OBUZ Z. (Executive), EMEKLİ S., ÇIRAK S., TOPALOĞLU P., TÜZÜN E., KÜÇÜKALİ C. İ., et al.

2018 - 2020

Nadir Nörodejeneratif Hastalıkların Moleküler Temellerinin Araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

YAPICI OBUZ Z. (Executive), MERCAN S., AKÇAKAYA N. H., UĞUR İŞERİ S. A.

2017 - 2017

32 novel pathogenic sequence variants in 253 DMD/BMD patients from Turkey

Project Supported by Higher Education Institutions , BAP Other

TOKSOY G. (Executive), BAGİROVA G., ALTUNOĞLU U., PARMAN F. Y., UYGUNER Z. O., OFLAZER Z. P., et al.

2016 - 2016

Clinical and Genetic Features of PKAN Patients in a Tertiary Center in Turkey

Project Supported by Higher Education Institutions , BAP Other

ÖZBEK U. (Executive), UĞUR İŞERİ S. A., HANAĞASI H. A., CEYLAN N. H., YAPICI Z., ERAKSOY M., et al.

Activities in Scientific Journals

2022 - Present

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Committee Member

Memberships and Roles in Scientific Organizations

2022 - Present

Türkiye Parkinson Hastalığı Derneği

Member

2022 - Present

European Paediatric Neurology Society

Member

2012 - Present

Çocuk ve Ergen Nörolojisi Derneği

Chairman

2004 - Present

Türk Nöroloji Derneği

Member

2001 - Present

Nöroimmunoloji Derneği

Member

1994 - Present

Epilepsi ile Savaş Derneği

Member

1992 - Present

Türkiye Spastik Çocuklar Vakfı

Member

Roles in Event Organizations

October 2024

9th International Symposium on NBIA

Scientific Congress

Yapıcı Obuz Z., Klopstock T., Hayflick S., Tiranti V., Elibol B., Emre M., et al.

İstanbul, Turkey

Congress and Symposium Activities

17 October 2024 - 19 October 2024

9th International Symposium on NBIA

Invited Speaker

İstanbul-Turkey

17 October 2024 - 19 October 2024

9th International Symposium on NBIA

Session Moderator

İstanbul-Turkey

06 June 2024 - 08 June 2024

I. Pediatrik Tıbbi Rehabilitasyon Kongresi

Panelists

İstanbul-Turkey

09 May 2024 - 12 May 2024